This study identifies ‘centers of endemism’ for typhlocybine leafhoppers in China, revealing diversity patterns and congruence of patterns between total species richness and endemism. Distribution patterns of 774 Typhlocybinae (607 described and 167 undescribed species) were mapped on a 1.5° × 1.5° latitude/longitude grid. Total species richness, endemic species richness and weighted endemism richness were calculated for each grid cell. Grid cells within the top 5% highest values of weighted endemism richness were considered as ‘centers of endemism’. Diversity patterns by latitude and altitude were obtained through calculating the gradient richness. A congruence of diversity patterns between total species richness and endemism was confirmed using correlation analysis. To investigate the bioclimatic factors (19 variables) contributing to the congruence between total species richness and endemism, we compared the factor's difference between non-endemic and endemic species using the Kruskal–Wallis test. Eleven centers of endemism, roughly delineated by mountain ranges, were identified in central and southern China, including the south Yunnan, Hengduan Mountains, Qinling Mountains, Hainan Island, Taiwan Island and six mountain areas located in western Sichuan, northwest Fujian, southeast Guizhou, southeast Hunan, central and western Guangdong, and north Zhejiang. Total species richness and endemic species richness decreased with increased latitude and had a consistent unimodal response to altitude. The proportions of endemism decreased with increased latitude and increased with rising altitude. Diversity patterns between total species richness and endemism were highly consistent, and ‘Precipitation of Coldest Period’ and ‘Temperature of Coldest Period’ may contribute to the congruence of pattern. Migration ability may play a role in the relationship of endemism and species richness; climate, environment factors and important geologic isolation events can also play crucial effects on relationships under special conditions.