Funding Information The authors acknowledge the financial support from the National Natural Science Foundation of China (No.: 21076123; 21276155).
Solubilization capacity of nonionic surfactant micelles exhibiting strong influence on export of intracellular pigments in Monascus fermentation
Article first published online: 20 FEB 2013
© 2013 The Authors. Microbial Biotechnology published by John Wiley & Sons Ltd and Society for Applied Microbiology
This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
Volume 6, Issue 5, pages 540–550, September 2013
How to Cite
Kang, B., Zhang, X., Wu, Z., Qi, H. and Wang, Z. (2013), Solubilization capacity of nonionic surfactant micelles exhibiting strong influence on export of intracellular pigments in Monascus fermentation. Microbial Biotechnology, 6: 540–550. doi: 10.1111/1751-7915.12039
- Issue published online: 14 AUG 2013
- Article first published online: 20 FEB 2013
- Manuscript Accepted: 7 JAN 2013
- Manuscript Received: 5 OCT 2012
- National Natural Science Foundation of China. Grant Numbers: 21076123, 21276155
In this study, perstractive fermentation of intracellular Monascus pigments in nonionic surfactant micelle aqueous solution had been studied. The permeability of cell membrane modified by nonionic surfactant might have influence on the rate of export of intracellular pigments into its extracellular broth while nearly no effect on the final extracellular pigment concentration. However, the solubilization of pigments in nonionic surfactant micelles strongly affected the final extracellular pigment concentration. The solubilization capacity of micelles depended on the kind of nonionic surfactant, the super-molecule assembly structure of nonionic surfactant in an aqueous solution, and the nonionic surfactant concentration. Elimination of pigment degradation by export of intracellular Monascus pigments and solubilizing them into nonionic surfactant micelles was also confirmed experimentally. Thus, nonionic surfactant micelle aqueous solution is potential for replacement of organic solvent for perstractive fermentation of intracellular product.