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Keywords:

  • children;
  • diabetes;
  • population-based data;
  • prevalence
  • 儿童,糖尿病,基于人口的数据,患病率

Abstract

Background

Population-based (PB) registries of type 1 diabetes mellitus (T1DM) in children have been essential in determining the geographic, racial, and temporal patterns of the disease. There is a paucity of PB data on the prevalence of type 1 and type 2 diabetes (T2DM) in youth.

Methods

The prevalence of diabetes in children was determined using a PB survey of the 628 schools in Philadelphia. Data obtained included type of diabetes, date of birth, race, gender, date of diagnosis, diabetes treatment, and most recent height and weight.

Results

The survey was completed by nurses at 510 schools (81% of schools) representing 252,896 children (70% of children in Philadelphia). Prevalence (per 1000) was computed. The survey identified 492 cases (355 T1DM, 88 T2DM, 49 type unknown). The overall prevalence of T1DM was 1.58 (0.73 White, 0.56 African American, 0.50 Hispanic); of T2DM was 0.35 (0.03 White, 0.28 African American, 0.05 Hispanic). Mean age at diagnosis was 8.6 and 11.9 years for T1DM and T2DM, respectively. The prevalence of T1DM was higher in boys- T2DM was higher in girls. Of children with T2DM, 25% were treated with insulin. BMI was ≥95th percentile in 20% of children weighed (10% of T1DM, 57% of T2DM).

Conclusions

Although the Philadelphia Pediatric Diabetes Registry is the longest ongoing US registry of its kind, these are the first PB diabetes prevalence data of children in Philadelphia. PB studies in schools are able to capture children with diabetes who are diagnosed and treated in a variety of settings.

摘要

背景

基于人口的1型糖尿病儿童登记表对于确定疾病的地理、种族以及时间规律来说很有必要。目前还缺乏有关青年人中1型与2型糖尿病患病率的基于人口的数据。

方法

在费城628所学校里采用基于人口的调查获取儿童中的糖尿病患病率。获取的数据包括糖尿病类型、出生日期、种族、性别、诊断日期、糖尿病治疗方案以及最近的身高与体重。

结果

由护士在510所学校(81%的学校)中对252896名儿童(70%的费城儿童)进行了调查。计算出(每1000名)患病率。这个调查鉴定出了492名病例(355名1型糖尿病,88名2型糖尿病,49名类型不明确)。1型糖尿病的总患病率为1.58(白人为0.73,非裔美国人为0.56,西班牙人裔为0.50);2型糖尿病为0.35(白人为0.03,非裔美国人为0.28,西班牙人裔为0.05)。诊断1型糖尿病与2型糖尿病时的平均年龄分别为8.6岁与11.9岁。男孩中的1型糖尿病患病率更高,而女孩中的2型糖尿病患病率更高。在2型糖尿病儿童中,有25%的人使用胰岛素治疗。有20%的儿童BMI超过了第95百分位(1型糖尿病有10%,2型糖尿病有57%)。

结论

虽然费城儿科糖尿病登记表在美国同类登记表中持续时间最长,但这些是费城儿童第一份基于人口的糖尿病患病率的数据。在学校中进行的基于人口的研究能够获得在不同的机构进行诊断与治疗的儿童糖尿病数据。