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Metabolic syndrome in psoriatic arthritis patients: A cross-sectional study

Authors

  • Aman Sharma,

    Corresponding author
    1. Department of Internal Medicine, Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh, India
    • Correspondence: Dr Aman Sharma, Division of Rheumatology, Department of Internal Medicine, Post Graduate Institute of Medical Education and Research,Chandigarh, India.

      Email: amansharma74@yahoo.com

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  • Dharmesh Gopalakrishnan,

    1. Department of Internal Medicine, Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh, India
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  • Ramesh Kumar,

    1. Department ofDermatology, Venereology & Leprology, Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh, India
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  • Rajesh Vijayvergiya,

    1. Department ofCardiology, Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh, India
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  • Sunil Dogra

    1. Department ofDermatology, Venereology & Leprology, Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh, India
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Abstract

Objectives

The major objective of our study was to assess the prevalence of metabolic syndrome in Indian patients with psoriatic arthritis.

Method

This was a one-time survey involving no follow-up. The study was performed among outpatients attending the speciality clinics of an institutional tertiary referral centre. A consecutive sample of 100 patients diagnosed as having psoriatic arthritis in our clinics was included in the study. Height, weight, body mass index, blood pressure and waist circumference of patients were measured at the enrolment visit. Venous samples were taken after 8 h of overnight fasting for the estimation of serum cholesterol, triglycerides and plasma glucose levels. The primary study outcome was the prevalence of metabolic syndrome in the study population.

Results

Fifty-eight and 59 patients had metabolic syndrome according to the Adult Treatment Panel III criteria and the consensus definition of metabolic syndrome for adult Asian patients, respectively. Patients with metabolic syndrome were older (< 0.001), with longer duration of psoriasis (= 0.017), and higher Bath Ankylosing Spondylitis Activity Index (= 0.016) than those without metabolic syndrome.

Conclusions

Metabolic syndrome is common in Asian Indian patients with psoriatic arthritis, especially in those with long-standing psoriasis and active joint disease.

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