This article describes an experimental murine acute otitis media model of Moraxella catarrhalis infection, and finds that expression of pili by this bacterial pathogen influences the infection by stimulating innate immune signaling.
Pili play an important role in enhancing the bacterial clearance from the middle ear in a mouse model of acute otitis media with Moraxella catarrhalis
Article first published online: 26 FEB 2013
© 2013 Federation of European Microbiological Societies. Published by Blackwell Publishing Ltd. All rights reserved
Pathogens and Disease
Volume 67, Issue 2, pages 119–131, March 2013
How to Cite
Kawano, T., Hirano, T., Kodama, S., Mitsui, M. T., Ahmed, K., Nishizono, A. and Suzuki, M. (2013), Pili play an important role in enhancing the bacterial clearance from the middle ear in a mouse model of acute otitis media with Moraxella catarrhalis. Pathogens and Disease, 67: 119–131. doi: 10.1111/2049-632X.12025
- Issue published online: 11 MAR 2013
- Article first published online: 26 FEB 2013
- Accepted manuscript online: 25 JAN 2013 10:16AM EST
- Manuscript Accepted: 8 JAN 2013
- Manuscript Revised: 7 JAN 2013
- Manuscript Received: 5 JUL 2012
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