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Fig. S1 Typical images of euploid (a), hypoploid (b) and hyerploid (c and d) oocytes.

Fig. S2 DFMO drinking water schedules.

Fig. S3 Metaphase I spindle morphology.

Table S1 Detailed breakdown of data listed in Table 1 (DFMO in vitro).

Table S2 Detailed breakdown of data listed in Table 3 (DFMO in vivo).

Table S3 Detailed breakdown of data listed in Table 4 (2-cell embryo karyotypes).

Table S4 Detailed breakdown of data listed in Table 5 (DFMO in F1 mice).

Table S5 detailed breakdown of data shown in Table 6 (heterozygous odc mice).

Table S6 Detailed breakdown of data listed in Table 7 (putrescine in older mice).

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