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Deficiency of ovarian ornithine decarboxylase contributes to aging-related egg aneuploidy in mice

  1. Yong Tao1,2,
  2. X. Johné Liu1,2,3,4,*

Article first published online: 26 NOV 2012

DOI: 10.1111/acel.12016

Issue

Aging Cell

Aging Cell

Volume 12, Issue 1, pages 42–49, February 2013

Additional Information

How to Cite

Tao, Y. and Liu, X. J. (2013), Deficiency of ovarian ornithine decarboxylase contributes to aging-related egg aneuploidy in mice. Aging Cell, 12: 42–49. doi: 10.1111/acel.12016

Author Information

  1. 1

    Ottawa Hospital Research Institute, Ottawa Hospital-General Campus, Ottawa, ON, Canada

  2. 2

    Faculty of Graduate and Postdoctoral Studies, University of Ottawa, Ottawa, ON, Canada

  3. 3

    Department of Obstetrics and Gynaecology, University of Ottawa, Ottawa, ON, Canada

  4. 4

    Department of Biochemistry, Microbiology and Immunology, University of Ottawa, Ottawa, ON, Canada

* Correspondence
X. Johné Liu, Ottawa Hospital Research Institute, The Ottawa Hospital - General Campus, 501 Smythe Road, box 511, Ottawa, K1H 6X9, Ontario. Tel: 613 798-5555 extn. 72906; Fax: 613 739-6968; e-mail: jliu@ohri.ca

Publication History

  1. Issue published online: 17 JAN 2013
  2. Article first published online: 26 NOV 2012
  3. Accepted manuscript online: 13 OCT 2012 08:24AM EST
  4. Manuscript Accepted: 2 OCT 2012

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Fig. S1 Typical images of euploid (a), hypoploid (b) and hyerploid (c and d) oocytes.

Fig. S2 DFMO drinking water schedules.

Fig. S3 Metaphase I spindle morphology.

Table S1 Detailed breakdown of data listed in Table 1 (DFMO in vitro).

Table S2 Detailed breakdown of data listed in Table 3 (DFMO in vivo).

Table S3 Detailed breakdown of data listed in Table 4 (2-cell embryo karyotypes).

Table S4 Detailed breakdown of data listed in Table 5 (DFMO in F1 mice).

Table S5 detailed breakdown of data shown in Table 6 (heterozygous odc mice).

Table S6 Detailed breakdown of data listed in Table 7 (putrescine in older mice).

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