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Fig. S1 Survival of long-lived strains following transient heat shock.

Fig. S2 Replicative lifespan curves of control strains sensitive to the tested stresses.

Fig. S3 Growth curves and lifespan curves of respiratory dead or deficient strains.

Fig. S4 Unsuppressed growth of afg3∆, yta12∆, and mrpl32∆ and corresponding lifespan curves.

Fig. S5 Cold incubation similarly impairs afg3∆ cell growth and longevity relative to rpl20b∆ cells.

Fig. S6 WT and afg3∆ cells do not perish after 24 h in YPD medium.

Table S1 Summary of long-lived mutants' resistance profile: Tunicamycin.

Table S2 Summary of long-lived mutants' resistance profile: Paraquat.

Table S3 Summary of long-lived mutants' resistance profile: Heat shock.

Table S4 Summary of long-lived mutants' resistance profile: MMS.

Table S5 Strain list.

Table S6 Lifespan statistics.

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