Cytogenetic analysis of human cells reveals specific patterns of DNA damage in replicative and oncogene-induced senescence
Article first published online: 25 DEC 2012
© 2012 The Authors Aging Cell © 2012 Blackwell Publishing Ltd/Anatomical Society of Great Britain and Ireland
Volume 12, Issue 2, pages 312–315, April 2013
How to Cite
Falcone, G., Mazzola, A., Michelini, F., Bossi, G., Censi, F., Biferi, M. G., Minghetti, L., Floridia, G., Federico, M., Musio, A. and Crescenzi, M. (2013), Cytogenetic analysis of human cells reveals specific patterns of DNA damage in replicative and oncogene-induced senescence. Aging Cell, 12: 312–315. doi: 10.1111/acel.12034
- Issue published online: 17 MAR 2013
- Article first published online: 25 DEC 2012
- Accepted manuscript online: 21 NOV 2012 12:49AM EST
- Manuscript Accepted: 5 NOV 2012
- Italian Association for Cancer Research
- PNR-CNR Aging Program. Grant Number: 2012-2014
- AIRC IG. Grant Number: 8804
Data S1. Methods.
Fig. S1. Stable and inducible p21 depletion in senescent fibroblasts.
Fig. S2. Characterization of senescent BJ fibroblasts.
Fig. S3. Characterization of OIS fibroblasts.
Fig. S4. hTERT expression in transduced C3PV fibroblasts.
Fig. S5. H2AX phosphorylation in RS and OIS cells.
Fig. S6. Expression of DDR markers in quiescent fibroblasts.
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