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acel12046-sup-0001-FigS1.tifimage/tif2156KFig. S1 Natural log-transformed relative risks (RR) of premature onset of CVD (diseases of heart and stroke) in the APOE e4 allele carriers compared with the non-e4 carriers at different examinations in the FHSO cohort stratified: (A) into younger (< 70) or older (70 +) group (defined next), (B) by sex, and (C) into younger or older group and by sex.
acel12046-sup-0002-FigS2.tifimage/tif2673KFig. S2 Natural log-transformed relative risks (RR) of premature onset of CVD (diseases of heart and stroke) in the APOE e4 allele carriers compared with the non-e4 carriers at different examinations in the (A) FHS and (B) FHSO cohorts.
acel12046-sup-0003-FigS3.tifimage/tif3032KFig. S3 Natural log-transformed relative risks (RR) of premature onset of CVD (diseases of heart and stroke) in the APOE e4 allele carriers compared with the non-e4 carriers at different examinations in the (A) FHS and (B) FHSO cohorts.
acel12046-sup-0004-FigS4.tifimage/tif2290KFig. S4 Associations of total cholesterol (log-base-10 transformed) with APOE in participants of different examinations in the (A) FHS and (B) FHSO cohorts.
acel12046-sup-0005-FigS5.tifimage/tif1179KFig. S5 Association of total cholesterol (log-base-10 transformed) with APOE in individuals who participated in each of the seven (A) FHS and (B) FHSO examinations (shown on outer x-axes).
acel12046-sup-0006-FigS6.tifimage/tif2439KFig. S6 Natural log-transformed relative risks (RR) of premature onset of CVD (diseases of heart and stroke) in carriers of the minor allele homozygous genotype (CC) of rs1042034 compared with the major allele (CT + TT) at different examinations in the (A) FHS and (B) FHSO cohorts.
acel12046-sup-0007-FigS7.tifimage/tif2258KFig. S7 Natural log-transformed relative risks (RR) of premature onset of CVD (diseases of heart and stroke) in carriers of the minor allele homozygous genotype (CC) of rs1042034 compared with the major allele (CT + TT) at different examinations in the (A) FHS and (B) FHSO cohorts.
acel12046-sup-0008-FigS8.tifimage/tif2067KFig. S8 Associations of total cholesterol (log-base-10 transformed) with rs1042034 in participants of different examinations in the (A) FHS and (B) FHSO cohorts.
acel12046-sup-0009-TableS1.docWord document218KTable S1 Association of total cholesterol with the selected genetic markers and age at onset of CVD in participants of the FHS examination 10 and the FHSO examination 4 stratified by fasting status.
acel12046-sup-0010-TableS2.docWord document170KTable S2 Basic characteristics of the genotyped FHS/FHSO participants.
acel12046-sup-0011-SupplementFigureLegends.docWord document33K 

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