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  • Allman D, Miller JP (2005) B cell development and receptor diversity during aging. Curr. Opin. Immunol. 17, 463467.
  • Alter-Wolf S, Blomberg B, Riley R (2009) Deviation of the B cell pathway in senescent mice is associated with reduced surrogate light chain expression and altered immature B cell generation, phenotype, and light chain expression. J. Immunol. 182, 138147.
  • Berg AH, Scherer PE (2005) Adipose tissue, inflammation, and cardiovascular disease. Circ. Res. 96, 939949.
  • Cancro M, Hao Y, Scholz J, Riley R, Frasca D, Dunn-Walters D, Blomberg BB (2009) B cells and aging: molecules and mechanisms. Trends Immunol. 30, 313318.
  • Feghali CA, Wright TM (1997) Cytokines in acute and chronic inflammation. Front Biosci 2, d12d26.
  • Frasca D, Nguyen D, Riley R, Blomberg BB (2003) Decreased E12 and/or E47 transcription factor activity in the bone marrow as well as in the spleen of aged mice. J. Immunol. 170, 719726.
  • Frasca D, Romero M, Diaz A, Alter-Wolf S, Ratliff M, Landin A, Riley R, Blomberg B (2012) A molecular mechanism for TNF-alpha-mediated downregulation of B cell responses. J. Immunol. 188, 279286.
  • Guerrettaz LM, Johnson SA, Cambier JC (2008) Acquired hematopoietic stem cell defects determine B-cell repertoire changes associated with aging. Proc Natl Acad Sci U S A 105, 1189811902.
  • Hao Y, O'Neill P, Naradikian M, Scholz J, Cancro MP (2011) A B-cell subset uniquely responsive to innate stimuli accumulates in aged mice. Blood 118, 12941304.
  • Hardy RR, Carmack CE, Shinton SA, Kemp JD, Hayakawa K (1991) Resolution and characterization of pro-B and pre-pro-B cell stages in normal mouse bone marrow. J. Exp. Med. 173, 12131225.
  • Keren Z, Averbuch D, Shahaf G, Zisman-Rozen S, Golan K, Itkin T, Lapidot T, Mehr R, Melamed D (2011a) Chronic B cell deficiency from birth prevents age-related alterations in the B lineage. J. Immunol. 187, 21402147.
  • Keren Z, Naor S, Nussbaum S, Golan K, Itkin T, Sasaki Y, Schmidt-Supprian M, Lapidot T, Melamed D (2011b) B-cell depletion reactivates B lymphopoiesis in the BM and rejuvenates the B lineage in aging. Blood 117, 31043112.
  • King AM, Van der Put E, Blomberg BB, Riley RL (2007) Accelerated Notch-dependent degradation of E47 proteins in aged B cell precursors is associated with increased ERK MAPK activation. J. Immunol. 178, 35213529.
  • King A, Keating P, Prabhu A, Blomberg B, Riley R (2009) NK cells in the CD19- B220 + bone marrow fraction are increased in senescence and reduce E2A and surrogate light chain proteins in B cell precursors. Mech. Ageing Dev. 130, 384392.
  • Kirman I, Zhao K, Wang Y, Szabo P, Telford W, Weksler ME (1998) Increased apoptosis of bone marrow pre-B cells in old mice associated with their low number. Int. Immunol. 10, 13851392.
  • Klinman NR, Kline GH (1997) The B-cell biology of aging. Immunol. Rev. 160, 103114.
  • Labrie J.E. 3rd, Sah A.P., Allman D.M., Cancro M.P., Gerstein R.M. (2004) Bone marrow microenvironmental changes underlie reduced RAG-mediated recombination and B cell generation in aged mice. J. Exp. Med. 200, 411423.
  • Leong K, Karsan A (2000) Signaling pathways mediated by tumor necrosis factor alpha. Histol. Histopathol. 15, 13031325.
  • Lescale C, Dias S, Maes J, Cumano A, Szabo P, Charron D, Weksler ME, Dosquet C, Vieira P, Goodhardt M (2010) Reduced EBF expression underlies loss of B-cell potential of hematopoietic progenitors with age. Aging Cell 9, 410419.
  • Linton PJ, Dorshkind K (2004) Age-related changes in lymphocyte development and function. Nat. Immunol. 5, 133139.
  • Merchant M, Garvy B, Riley R (1996) Autoantibodies inhibit interleukin-7-mediated proliferation and are associated with the age-dependent loss of pre-B cells in autoimmune New Zealand Black Mice. Blood 87, 32893296.
  • Middendorp S, Dingjan GM, Maas A, Dahlenborg K, Hendriks RW (2003) Function of Bruton's tyrosine kinase during B cell development is partially independent of its catalytic activity. J. Immunol. 171, 59885996.
  • Miller J, Allman D (2003) The decline in B lymphopoiesis in aged mice reflects loss of very early B-lineage precursors. J. Immunol. 171, 23262330.
  • Muller-Sieburg CE, Sieburg HB, Bernitz JM, Cattarossi G (2012) Stem cell heterogeneity: implications for aging and regenerative medicine. Blood 119, 39003907.
  • Osmond DG, Kim N, Manoukian R, Phillips RA, Rico-Vargas SA, Jacobsen K (1992) Dynamics and localization of early B-lymphocyte precursor cells (pro-B cells) in the bone marrow of scid mice. Blood 79, 16951703.
  • Pillai S, Cariappa A (2008) The bone marrow perisinusoidal niche for recirculating B cells and the positive selection of bone marrow-derived B lymphocytes. Immunol. Cell Biol. 87, 1619.
  • Riley RL, Kruger MG, Elia J (1991) B cell precursors are decreased in senescent BALB/c mice, but retain normal mitotic activity in vivo and in vitro. Clin. Immunol. Immunopathol. 59, 301313.
  • Riley RL, Blomberg BB, Frasca D (2005) B cells, E2A, and aging. Immunol. Rev. 205, 3047.
  • Rolink A, Karasuyama H, Grawunder U, Haasner D, Kudo A, Melchers F (1993) B cell development in mice with a defective lambda 5 gene. Eur. J. Immunol. 23, 12841288.
  • Rolink AG, Winkler T, Melchers F, Andersson J (2000) Precursor B cell receptor-dependent B cell proliferation and differentiation does not require the bone marrow or fetal liver environment. J. Exp. Med. 191, 2332.
  • Rubtsov A, Rubtsova K, Fischer A, Meehan R, Gillis J, Kappler J, Marrack P (2011) Toll-like receptor 7 (TLR7)-driven accumulation of a novel CD11c(+) B-cell population is important for the development of autoimmunity. Blood 118, 13051315.
  • Sen J, Rosenberg N, Burakoff SJ (1990) Expression and ontogeny of CD2 on murine B cells. J. Immunol. 144, 29252930.
  • Sherwood E, Blomberg B, Xu W, Warner C, Riley R (1998) Senescent BALB/c mice exhibit decreased expression of lambda5 surrogate light chains and reduced development within the pre-B cell compartment. J. Immunol. 161, 44724475.
  • Sherwood E, Xu W, King A, Blomberg B, Riley RL (2000) The reduced expression of surrogate light chains in B cell precursors from senescent BALB/c mice is associated with decreased E2A proteins. Mech. Ageing Dev. 118, 4559.
  • Sherwood E, Xu W, Riley R (2003) B cell precursors in senescent mice exhibit decreased recruitment into proliferative compartments and altered expression of Bcl-2 family members. Mech. Ageing Dev. 124, 147153.
  • Song H, Price PW, Cerny J (1997) Age-related changes in antibody repertoire: contribution from T cells. Immunol. Rev. 160, 5562.
  • Stephan RP, Sanders VM, Witte PL (1996) Stage-specific alterations in murine B lymphopoiesis with age. Int. Immunol. 8, 509518.
  • Stephan RP, Lill-Elghanian DA, Witte PL (1997) Development of B cells in aged mice: decline in the ability of pro-B cells to respond to IL-7 but not to other growth factors. J. Immunol. 158, 15981609.
  • Stephan RP, Reilly CR, Witte PL (1998) Impaired ability of bone marrow stromal cells to support B-lymphopoiesis with age. Blood 91, 7588.
  • Ueda Y, Yang K, Foster SJ, Kondo M, Kelsoe G (2004) Inflammation Controls B Lymphopoiesis by Regulating Chemokine CXCL12 Expression. J. Exp. Med. 199, 4758.
  • Van Den Broeck A, Cambier J (2011) B cells talk to their progenitors. Blood 117, 29852986.
  • Van der Put E, Sherwood EM, Blomberg BB, Riley RL (2003) Aged mice exhibit distinct B cell precursor phenotypes differing in activation, proliferation and apoptosis. Exp. Gerontol. 38, 11371147.
  • Van der Put E, Frasca D, King AM, Blomberg BB, Riley RL (2004) Decreased E47 in senescent B cell precursors is stage specific and regulated posttranslationally by protein turnover. J. Immunol. 173, 818827.
  • Wilson E, King A, Sherwood E, Riley R (2005) Pre-B cell loss in senescence coincides with preferential development of immature B cells characterized by partial activation and altered Vh repertoire. Exp. Gerontol. 40, 6779.
  • Yanaba K, Bouaziz J-D, Matsushita T, Tsubata T, Tedder TF (2009) The development and function of regulatory B cells expressing IL-10 (B10 cells) requires antigen receptor diversity and TLR signals. J. Immunol. 182, 74597472.