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Fig. S1 Suppressive MDSCs increase with age in lymph nodes.

Fig. S2 Macrophages from geriatric mice are capable of responding to M1 or M2 stimuli.

Fig. S3 Tumor supernatant induces M2 macrophages regardless of age.

Fig. S4 Macrophages from geriatric mice can induce CD4+ T cell Proliferation.

Fig. S5 Macrophages from young mice can induce proliferation of CD4+ T cells from geriatric mice.

Fig. S6 Macrophages from young mice can induce proliferation of CD8+ T cells from geriatric mice.

Fig. S7 IL-2/CD40 activated macrophages from young and geriatric mice secrete TNF-α, IFN-γ and IL-12.

Fig. S8 IL-2/CD40 activated macrophages from young and geriatric mice induce greater T cell divisions.

Fig. S9 IL-2/CD40 activated macrophages from young mice induce greater cell division of both young and geriatric T cells.

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