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acel12081-sup-0001-FigS1.epsimage/eps2274KFig. S1 Conservation of FLCN and C. elegans sequence determination by sequencing.
acel12081-sup-0002-FigS2.epsimage/eps113KFig. S2 qPCR analysis reveals expression levels of HIF-1 and DAF-16 target genes not to be affected in the flcn-1-mutant strain.
acel12081-sup-0003-FigS3.tifimage/tif9049KFig. S3 Loss of flcn-1 does not induce nuclear translocation of DAF-16.
acel12081-sup-0004-FigS4.epsimage/eps202KFig. S4 Phenotyping flcn-1-mutant worms.
acel12081-sup-0005-FigS5.epsimage/eps128KFig. S5 Overexpression of flcn-1 does not alter thermotolerance.
acel12081-sup-0006-FigS6.epsimage/eps1941KFig. S6 Functional annotation clustering.
acel12081-sup-0007-FigS7.epsimage/eps945KFig. S7 Comparison to published microarrays.
acel12081-sup-0008-TableS1.epsimage/eps1453KTable S1 Statistics of lifespan experiments examining the role of flcn-1.
acel12081-sup-0009-TableS2.epsimage/eps1614KTable S2 Statistics of lifespan experiments examining the genetic interaction with hif-1.
acel12081-sup-0010-TableS3.epsimage/eps1421KTable S3 Statistics of lifespan experiments examining the genetic interaction with daf-16.
acel12081-sup-0011-TableS4.xlsapplication/msexcel24KTables S4 Pooled lifespan data underlying the lifespan curves in Figure 2 specifying the number of worms that entered, died, or were censored during the interval.
acel12081-sup-0012-TableS5.xlsapplication/msexcel39KTables S5 Pooled lifespan data underlying the lifespan curves in Figure 3 specifying the number of worms that entered, died, or were censored during the interval.
acel12081-sup-0013-TableS6.xlsapplication/msexcel30KTables S6 Pooled lifespan data underlying the lifespan curves in Figure 4 specifying the number of worms that entered, died, or were censored during the interval.
acel12081-sup-0014-TableS7.xlsxapplication/msexcel67KTable S7 Differentially expressed genes in flcn-1-mutant worms compared to WTN2 as determined by Agilent whole-genome microarrays.
acel12081-sup-0015-MovieS1.MOVvideo/mov1438KMovie S1 Tissue-specific activity of the flcn-1 promoter. Movies show Z-stacks with a fixed distance of 1 μm of TMB100 (unc-119 (ed3); klnIs2 [Pflcn-1::GFP + unc-119 (+)]). 1. Adult hermaphrodite head.
acel12081-sup-0016-MovieS2.MOVvideo/mov1761KMovie S2 Tissue-specific activity of the flcn-1 promoter. Movies show Z-stacks with a fixed distance of 1 μm of TMB100 (unc-119 (ed3); klnIs2 [Pflcn-1::GFP + unc-119 (+)]). 2. Adult hermaphrodite midbody.
acel12081-sup-0017-MovieS3.MOVvideo/mov4842KMovie S3 Tissue-specific activity of the flcn-1 promoter. Movies show Z-stacks with a fixed distance of 1 μm of TMB100 (unc-119 (ed3); klnIs2 [Pflcn-1::GFP + unc-119 (+)]). 3. Adult hermaphrodite midbody.
acel12081-sup-0018-MovieS4.MOVvideo/mov1347KMovie S4 Tissue-specific activity of the flcn-1 promoter. Movies show Z-stacks with a fixed distance of 1 μm of TMB100 (unc-119 (ed3); klnIs2 [Pflcn-1::GFP + unc-119 (+)]). 4. Adult hermaphrodite tail.
acel12081-sup-0019-Methods.docWord document35KData S1 Suppl. methods.

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