Deletion of the major peroxiredoxin Tsa1 alters telomere length homeostasis
Version of Record online: 15 MAY 2013
Published 2013. This article is a U.S. Government work and is in the public domain in the USA.
Volume 12, Issue 4, pages 635–644, August 2013
How to Cite
Lu, J., Vallabhaneni, H., Yin, J. and Liu, Y. (2013), Deletion of the major peroxiredoxin Tsa1 alters telomere length homeostasis. Aging Cell, 12: 635–644. doi: 10.1111/acel.12085
- Issue online: 16 JUL 2013
- Version of Record online: 15 MAY 2013
- Accepted manuscript online: 17 APR 2013 05:44AM EST
- Manuscript Accepted: 6 APR 2013
- Intramural Research Program of the NIA, National Institutes of Health
Fig. S1 Deletion of the TSA1 gene causes increase ROS in 20% oxygen conditon.
Fig. S2 Sequence alignment of telomere XV-L from the wild type (A) and tsa1 mutant (B).
Fig. S3 Senescence and telomere length are similar between the tsa1 and tsa1 est2 mutants.
Fig. S4 Expression of telomerase subunits and telomerase activity are not changed in the tsa1 mutant.
Fig. S5 Telomere length analysis of a strain carrying URA3-Telomere.
Fig. S6 Measurement for oxidative DNA lesions in the tsa1 mutant.
Fig. S7 Measurement for DNA blocking lesions in telomere DNA.
Table S1 Primers used in quantitative PCR.
Data S1 Yeast strains and genetic procedures.
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