An age-related numerical and functional deficit in CD19+CD24hiCD38hi B cells is associated with an increase in systemic autoimmunity
Article first published online: 19 JUL 2013
© 2013 The Authors. Aging Cell published by the Anatomical Society and John Wiley & Sons Ltd.
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Volume 12, Issue 5, pages 873–881, October 2013
How to Cite
Duggal, N. A., Upton, J., Phillips, A. C., Sapey, E. and Lord, J. M. (2013), An age-related numerical and functional deficit in CD19+CD24hiCD38hi B cells is associated with an increase in systemic autoimmunity. Aging Cell, 12: 873–881. doi: 10.1111/acel.12114
- Issue published online: 11 SEP 2013
- Article first published online: 19 JUL 2013
- Accepted manuscript online: 11 JUN 2013 10:33AM EST
- Manuscript Accepted: 3 JUN 2013
- Research Councils UK New Dynamics of Ageing initiative. Grant Number: RES-356-25-0011
Fig. S1 PBMCs were isolated from peripheral blood, stimulated using (A) anti-CD3 antibody or (B) LPS for 72 h and immunostained for expression of CD19, CD24, CD38 and intracellularly stained to measure IL10.
Fig. S2 PBMCs were isolated from peripheral blood, stimulated using anti-CD3 antibody for 72 h and immunostained for expression of CD19, CD1d, CD5 and intracellularly stained to measure IL10.
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