Senescence-associated lncRNAs: senescence-associated long noncoding RNAs
Article first published online: 14 JUL 2013
Published 2013. This article is a U.S. Government work and is in the public domain in the USA.
Volume 12, Issue 5, pages 890–900, October 2013
How to Cite
Abdelmohsen, K., Panda, A., Kang, M.-J., Xu, J., Selimyan, R., Yoon, J.-H., Martindale, J. L., De, S., Wood, W. H., Becker, K. G. and Gorospe, M. (2013), Senescence-associated lncRNAs: senescence-associated long noncoding RNAs. Aging Cell, 12: 890–900. doi: 10.1111/acel.12115
- Issue published online: 11 SEP 2013
- Article first published online: 14 JUL 2013
- Accepted manuscript online: 13 JUN 2013 02:30AM EST
- Manuscript Accepted: 5 JUN 2013
Fig. S1 SAL-RNA levels in proliferating (untreated) and senescent (IR) WI-38 cells.
Fig. S2 SAL-RNA levels in proliferating (P, PDL 25) and pre-senescent (S, PDL 49) IMR-90 cells.
Fig. S3 SAL-RNAs differentially expressed in WI-38 fibroblasts (untreated versus IR) and in IMR-90 (proliferating versus late-passage).
Fig. S4 Northern blot analysis of the levels of lncRNAs SAL-RNA1 (XLOC_023166), SAL-RNA2 (XLOC_025931), SAL-RNA3 (XLOC_025918), as well as loading control 18S rRNA in P and S WI-38 cells.
Fig. S5 (A) Top, sequence of novel SAL-RNA XLOC_023166, preferentially expressed in proliferating WI-38 fibroblasts and genomic region containing XLOC_023166.
Table S1 Additional information on naturally occurring antisense transcripts (NA)-SAL-RNAs differentially expressed in P relative to S WI-38 fibroblasts, as identified by RNA-Seq analysis.
Table S2 Additional information on pseudogene-encoded (PE) lncRNAs differentially expressed in P relative to S WI-38 fibroblasts, as identified by RNA-Seq analysis.
Table S3 Additional information of other known lncRNAs differentially expressed in P relative to S WI-38 fibroblasts, as identified by RNA-Seq analysis.
Table S4 Additional details of novel lncRNAs expressed more highly in proliferating WI-38 fibroblasts, identified by RNA-Seq analysis.
Table S5 Additional details of novel lncRNAs expressed more highly in senescent WI-38 fibroblasts, identified by RNA-Seq analysis.
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