SEARCH

SEARCH BY CITATION

References

  • Atzori C, Ghetti B, Piva R, Srinivasan AN, Zolo P, Delisle MB, Mirra SS, Migheli A (2001) Activation of JNK/p38 pathway occurs in diseases characterized by tau protein pathology and is related to tau phosphorylation but not to apoptosis. J. Neuropathol. Exp. Neurol. 60, 11901197.
  • Brash AR (1999) Lipoxygenases: occurrence, functions, catalysis and acquisition of substrate. J. Biol. Chem. 274, 2367923682.
  • Chinnici CM, Yao Y, Ding T, Funk CD, Praticò D (2005) Absence of 12/15 lipoxygenase reduces brain oxidative stress in apolipoprotein E-deficient mice. Am. J. Pathol. 167, 13711377.
  • Chu J, Giannopoulos PF, Ceballos-Diaz C, Golde T, Pratico D (2012a) Adeno-associated virus-mediated brain delivery of 5-Lipoxygenase modulates the AD-like phenotype of APP mice. Mol. Neurodegener. 7, 1.
  • Chu J, Zhuo JM, Pratico D (2012b) Transcriptional regulation of βsecretase-1 by 12/15-lipoxygenase results in enhanced amyloidogenesis and cognitive impairments. Ann. Neurol. 71, 5767.
  • Feinmark SJ, Begum R, Tsvetkov E, Goussakov I, Funk CD, Siegelbaum SA, Bolshakov VY (2003) 12-Lipoxygenase metabolites of arachidonic acid mediate metabotropic glutamate receptor-dependent long-term depression at hippocampal CA3-CA1 synapses. J. Neurosci. 23, 1142711435.
  • Gong CX, Iqbal K (2008) Hyperphosphorylation of microtubule-associated protein tau: a promising therapeutic target for Alzheimer disease. Curr. Med. Chem. 15, 23212328.
  • Hsiao K, Chapman P, Nilsen S, Eckman C, Harigaya Y, Younkin S, Yang F, Cole G (1996) Correlative memory deficits, Aβ elevation, and amyloid plaques in transgenic mice. Science 274, 99102.
  • Humbert S, Dhavan R, Tsai LH (2000) p39 activates cdk5 in neurons, and is associated with the actin cytoskeleton. J. Cell Sci. 113, 975983.
  • Iwakiri M, Mizukami K, Ikonomovic MD, Ishikawa M, Abrahamson EE, DeKosky ST, Asada T (2009) An immunohistochemical study of GABA receptor gamma subunits in Alzheimer's disease hippocampus: relationship to neurofibrillary tangle progression. Neuropathology 29, 263269.
  • Joshi YB, Chu J, Pratico D (2012) Stress hormone leads to memory deficits and altered tau phosphorylation in a mouse model of Alzheimer's disease. J. Alzheimers Dis. 31, 167176.
  • Kuhn H, Saam J, Eibach S, Holzhütter HG, Ivanov I, Walther M (2005) Structural biology of mammalian lipoxygenases: enzymatic consequences of targeted alterations of the protein structure. Biochem. Biophys. Res. Commun. 338, 93101.
  • Lebeau A, Terro F, Rostene W, Pelaprat D (2004) Blockade of 12-lipoxygenase expression protects cortical neurons from apoptosis induced by β-amyloid peptide. Cell Death Differ. 11, 875884.
  • Lee MS, Tsai LH (2003) Cdk5: one of the links between senile plaques and neurofibrillary tangles? J. Alzheimers Dis. 5, 127137.
  • Li Y, Maher P, Schubert DA (1997) Role of 12-lipoxygenase in nerve cell death caused by glutathione depletion. Neuron 19, 453463.
  • Liu SJ, Zhang AH, Li HL, Wang Q, Deng HM, Netzer WJ, Xu H, Wang JZ (2003) Overactivation of glycogen synthase kinase-3 by inhibition of phosphoinositol-3 kinase and protein kinase C leads to hyperphosphorylation of tau and impairment of spatial memory. J. Neurochem. 87, 13331344.
  • Martin L, Latypova X, Terro F (2011) Post-translational modifications of tau protein: implications for Alzheimer's disease. Neurochem. Int. 58, 458471.
  • Masliah E, Mallory M, Alford M, De Teresa R, Hansen LA, McKee DW Jr, Morris JC (2001) Altered expression of synaptic proteins occurs early during progression of Alzheimer's disease. Neurology 56, 127129.
  • Oddo S, Caccamo A, Tseng B, Cheng D, Vasilevko V, Cribbs DH, LaFerla FM (2008) Blocking Abeta 42 accumulation delays the onset and progression of tau pathology via the C terminus of the heat shock protein 70-interacting protein: a mechanistic link between Abeta and tau pathology. J. Neurosci. 28, 1216312175.
  • Praticò D, Zhukareva V, Yao Y, Uryu K, Funk CD, Lawson JA, Trojanowski JQ, Lee VM (2004) 12/15-Lipoxygenase is increased in Alzheimer's disease. Possible involvement in brain oxidative stress. Am. J. Pathol. 164, 16551662.
  • Puccio S, Chu J, Praticò D (2011) Involvement of 5-lipoxygenase in the corticosteroid-dependent amyloid beta formation: in vitro and in vivo evidence. PLoS ONE 6, e15163.
  • Querferth HW, Laferla FM (2010) Alzheimer's Disease. New Eng. J. Med. 362, 329344.
  • Savage MJ, Lin YG, Ciallella JR, Flood DG, Scott RW (2002) Activation of c-Jun N-terminal kinase and p38 in an Alzheimer's disease model is associated with amyloid deposition. J. Neurosci. 22, 33763385.
  • Sun W, Qureshi HY, Cafferty PW, Sobue K, Agarwal-Mawal A, Neufield KD, Paudel HK (2002) Glycogen synthase kinase-beta is complexed with tau protein in brain microtubules. J. Biol. Chem. 277, 1193311940.
  • Yang H, Zhuo JM, Chu J, Chinnici C, Praticò D (2010) Amelioration of the Alzheimer's disease phenotype by absence of 12/15lipoxygenase. Biol. Psychiatry 68, 922929.
  • Yao Y, Clark CM, Trojanowski JQ, Lee VM, Praticò D (2005) Elevation of 12/15 lipoxygenase products in AD and mild cognitive impairment. Ann. Neurol. 58, 623626.
  • Zhuo JM, Praticò D (2010) Acceleration of brain amyloidosis in an Alzheimer's disease mouse model by a folate, vitamin B6 and B12-deficient diet. Exp. Gerontol. 45, 195201.