A dual role of the Wnt signaling pathway during aging in Caenorhabditis elegans
Article first published online: 1 SEP 2013
© 2013 the Anatomical Society and John Wiley & Sons Ltd
Volume 13, Issue 1, pages 8–18, February 2014
How to Cite
Lezzerini, M. and Budovskaya, Y. (2014), A dual role of the Wnt signaling pathway during aging in Caenorhabditis elegans. Aging Cell, 13: 8–18. doi: 10.1111/acel.12141
- Issue published online: 16 JAN 2014
- Article first published online: 1 SEP 2013
- Accepted manuscript online: 23 JUL 2013 09:57AM EST
- Manuscript Accepted: 16 JUL 2013
- NIH office of Research Infrastructure Programs. Grant Number: P40 OD010440
- MacGillavry fellowship at the University of Amsterdam
Fig. S1 Expression patterns of lin-44pro::4xNLSGFP, elt-20pro::4xNLS GFP, and mom-2pro::4xNLS GFP Wnt ligands during aging.
Fig. S2 Expression patterns cwn-1pro::4xNLSGFP and cwn-2pro::4xNLSGFP Wnt ligands in young adult worms.
Fig. S3 Post-translational stability of ELT-3 GATA is not affected in Wnts RNAi treatment.
Fig. S4 mom-2(RNAi) treatment does not slow the rate of reproduction of wild type worms.
Table S1 The median life span of the wild type and Wnt ligand mutant worms does not change after exposure to the cellular or the oxidative stress.
Table S2 Strains used in this study.
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