Lifespan extension by dietary intervention in a mouse model of Cockayne Syndrome uncouples early postnatal development from segmental progeria
Article first published online: 11 SEP 2013
© 2013 the Anatomical Society and John Wiley & Sons Ltd
Volume 12, Issue 6, pages 1144–1147, December 2013
How to Cite
Brace, L. E., Vose, S. C., Vargas, D. F., Zhao, S., Wang, X.-P. and Mitchell, J. R. (2013), Lifespan extension by dietary intervention in a mouse model of Cockayne Syndrome uncouples early postnatal development from segmental progeria. Aging Cell, 12: 1144–1147. doi: 10.1111/acel.12142
- Issue published online: 21 NOV 2013
- Article first published online: 11 SEP 2013
- Accepted manuscript online: 29 JUL 2013 09:35AM EST
- Manuscript Accepted: 10 JUL 2013
- Interdisciplinary Genes and Environment. Grant Number: T32ES016645
- Radiation Biology. Grant Number: T32CA009078
- Glenn Foundation for Medical Research
- Luke O'Brien Foundation
Fig. S1 Modulation of macronutrient content of milk by diet. A–C.
Fig. S2 Propensity of LFD pellets to absorb moisture.
Fig. S3 Normal lean body mass as a function of weight in CX mutants. A.
Fig. S4 Neurological abnormalities in CX mice. A.
Fig. S5 Progressive loss of hind limb coordination culminating in paralysis. A.
Fig. S6 Kyphosis in CX mice.
Fig. S7 Normal tooth development in CX mutants. A–C.
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