• Ashcroft GS, Roberts AB (2000) Loss of Smad3 modulates wound healing. Cytokine Growth Factor Rev. 11, 125131.
  • Ashcroft GS, Horan MA, Ferguson MW (1995) The effects of ageing on cutaneous wound healing in mammals. J. Anat. 187(Pt 1), 126.
  • Ashcroft GS, Mills SJ, Ashworth JJ (2002) Ageing and wound healing. Biogerontology 3, 337345.
  • Axelrod D, Koppel DE, Schlessinger J, Elson E, Webb WW (1976) Mobility measurement by analysis of fluorescence photobleaching recovery kinetics. Biophys. J. 16, 10551069.
  • Bernert B, Porsch H, Heldin P (2011) Hyaluronan synthase 2 (HAS2) promotes breast cancer cell invasion by suppression of tissue metalloproteinase inhibitor 1 (TIMP-1). J. Biol. Chem. 286, 4234942359.
  • Bourguignon LY, Ramez M, Gilad E, Singleton PA, Man MQ, Crumrine DA, Elias PM, Feingold KR (2006) Hyaluronan-CD44 interaction stimulates keratinocyte differentiation, lamellar body formation/secretion, and permeability barrier homeostasis. J. Invest. Dermatol. 126, 13561365.
  • Chou YT, Lin HH, Lien YC, Wang YH, Hong CF, Kao YR, Lin SC, Chang YC, Lin SY, Chen SJ, Chen HC, Yeh SD, Wu CW (2010) EGFR promotes lung tumorigenesis by activating miR-7 through a Ras/ERK/Myc pathway that targets the Ets2 transcriptional repressor ERF. Cancer Res. 70, 88228831.
  • Gabbiani G (2003) The myofibroblast in wound healing and fibrocontractive diseases. J. Pathol. 200, 500503.
  • Ito T, Williams JD, Fraser D, Phillips AO (2004a) Hyaluronan attenuates transforming growth factor-beta1-mediated signaling in renal proximal tubular epithelial cells. Am. J. Pathol. 164, 19791988.
  • Ito T, Williams JD, Fraser DJ, Phillips AO (2004b) Hyaluronan regulates transforming growth factor-beta1 receptor compartmentalization. J. Biol. Chem. 279, 2532625332.
  • Kefas B, Godlewski J, Comeau L, Li Y, Abounader R, Hawkinson M, Lee J, Fine H, Chiocca EA, Lawler S, Purow B (2008) microRNA-7 inhibits the epidermal growth factor receptor and the Akt pathway and is down-regulated in glioblastoma. Cancer Res. 68, 35663572.
  • Kohan M, Muro AF, White ES, Berkman N (2010) EDA-containing cellular fibronectin induces fibroblast differentiation through binding to alpha4beta7 integrin receptor and MAPK/Erk 1/2-dependent signaling. FASEB J. 24, 45034512.
  • Kultti A, Karna R, Rilla K, Nurminen P, Koli E, Makkonen KM, Si J, Tammi MI, Tammi RH (2010) Methyl-beta-cyclodextrin suppresses hyaluronan synthesis by down-regulation of hyaluronan synthase 2 through inhibition of Akt. J. Biol. Chem. 285, 2290122910.
  • Li X, Carthew RW (2005) A microRNA mediates EGF receptor signaling and promotes photoreceptor differentiation in the Drosophila eye. Cell 123, 12671277.
  • Meran S, Steadman R (2011) Fibroblasts and myofibroblasts in renal fibrosis. Int. J. Exp. Pathol. 92, 158167.
  • Meran S, Thomas D, Stephens P, Martin J, Bowen T, Phillips A, Steadman R (2007) Involvement of hyaluronan in regulation of fibroblast phenotype. J. Biol. Chem. 282, 2568725697.
  • Meran S, Luo DD, Simpson R, Martin J, Wells A, Steadman R, Phillips AO (2011) Hyaluronan facilitates transforming growth factor-beta1-dependent proliferation via CD44 and epidermal growth factor receptor interaction. J. Biol. Chem. 286, 1761817630.
  • Midgley A, Rogers M, Hallett M, Clayton A, Bowen T, Phillips A, Steadman R (2013) TGF-β1-stimulated fibroblast to myofibroblast differentiation is mediated by HA-facilitated EGFR and CD44 co-localisation in lipid rafts. J. Biol. Chem. 288, 1482414838.
  • Palyi-Krekk Z, Barok M, Kovacs T, Saya H, Nagano O, Szollosi J, Nagy P (2008) EGFR and ErbB2 are functionally coupled to CD44 and regulate shedding, internalization and motogenic effect of CD44. Cancer Lett. 263, 231242.
  • Sherman L, Sleeman J, Herrlich P, Ponta H (1994) Hyaluronate receptors: key players in growth, differentiation, migration and tumor progression. Curr. Opin. Cell Biol. 6, 726733.
  • Shiraha H, Gupta K, Drabik K, Wells A (2000) Aging fibroblasts present reduced epidermal growth factor (EGF) responsiveness due to preferential loss of EGF receptors. J. Biol. Chem. 275, 1934319351.
  • Simpson RM, Meran S, Thomas D, Stephens P, Bowen T, Steadman R, Phillips A (2009) Age- related changes in pericellular hyaluronan organization leads to impaired dermal fibroblast to myofibroblast differentiation. Am. J. Pathol. 175, 19151928.
  • Simpson RM, Wells A, Thomas D, Stephens P, Steadman R, Phillips A (2010) Aging fibroblasts resist phenotypic maturation because of impaired hyaluronan-dependent CD44/epidermal growth factor receptor signaling. Am. J. Pathol. 176, 12151228.
  • Wang SJ, Bourguignon LY (2006a) Hyaluronan-CD44 promotes phospholipase C-mediated Ca2 +  signaling and cisplatin resistance in head and neck cancer. Arch. Otolaryngol. Head Neck Surg. 132, 1924.
  • Wang SJ, Bourguignon LY (2006b) Hyaluronan and the interaction between CD44 and epidermal growth factor receptor in oncogenic signaling and chemotherapy resistance in head and neck cancer. Arch. Otolaryngol. Head Neck Surg. 132, 771778.
  • Webber J, Jenkins RH, Meran S, Phillips A, Steadman R (2009) Modulation of TGFbeta1- dependent myofibroblast differentiation by hyaluronan. Am. J. Pathol. 175, 148160.
  • Webster RJ, Giles KM, Price KJ, Zhang PM, Mattick JS, Leedman PJ (2009) Regulation of epidermal growth factor receptor signaling in human cancer cells by microRNA-7. J. Biol. Chem. 284, 57315741.