Understanding epigenetic changes in aging stem cells – a computational model approach
Version of Record online: 15 JAN 2014
© 2013 The Authors. Aging Cell published by the Anatomical Society and John Wiley & Sons Ltd.
This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
Volume 13, Issue 2, pages 320–328, April 2014
How to Cite
Przybilla, J., Rohlf, T., Loeffler, M. and Galle, J. (2014), Understanding epigenetic changes in aging stem cells – a computational model approach. Aging Cell, 13: 320–328. doi: 10.1111/acel.12177
- Issue online: 11 MAR 2014
- Version of Record online: 15 JAN 2014
- Manuscript Accepted: 15 OCT 2013
- Federal Ministry of Education and Research (BMBF). Grant Number: FKZ 031 6065
- MAGE. Grant Number: 50500541
Fig. S1 Stability of histone modification states.
Fig S2 Stable phenotypes with cell exchange between α and Ω.
Fig. S3 ARP with changed proliferation and differentiation properties.
Fig. S4 Phenotypic changes are controlled by DNA-methylation.
Fig. S5 Artificial Genome Model.
Fig. S6 Transcriptional regulation by histone modification.
Table S1 Model parameters.
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