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Fig. S1 Stability of histone modification states.

Fig S2 Stable phenotypes with cell exchange between α and Ω.

Fig. S3 ARP with changed proliferation and differentiation properties.

Fig. S4 Phenotypic changes are controlled by DNA-methylation.

Fig. S5 Artificial Genome Model.

Fig. S6 Transcriptional regulation by histone modification.

Table S1 Model parameters.

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