The GATA transcription factor/MTA-1 homolog egr-1 promotes longevity and stress resistance in Caenorhabditis elegans
Article first published online: 6 DEC 2013
© 2013 The Authors. Aging Cell published by the Anatomical Society and John Wiley & Sons Ltd.
This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
Volume 13, Issue 2, pages 329–339, April 2014
How to Cite
Zimmerman, S. M. and Kim, S. K. (2014), The GATA transcription factor/MTA-1 homolog egr-1 promotes longevity and stress resistance in Caenorhabditis elegans. Aging Cell, 13: 329–339. doi: 10.1111/acel.12179
- Issue published online: 11 MAR 2014
- Article first published online: 6 DEC 2013
- Accepted manuscript online: 5 DEC 2013 05:41AM EST
- Manuscript Accepted: 18 OCT 2013
- National Institutes of Health. Grant Number: R01AGO25941
|acel12179-sup-0001-FigS1.pdf||application/PDF||227K||Fig. S1 egr-1 RNA is overexpressed in egr-1 overexpression lines, and increases with age in all genotypes.|
|acel12179-sup-0002-FigS2.pdf||application/PDF||184K||Fig. S2 Brood size of EGR-1 overexpression lines.|
|acel12179-sup-0003-FigS3.pdf||application/PDF||267K||Fig. S3 egr-1 RNAi reduces resistance to oxidative and UV stress, but not heat stress.|
|acel12179-sup-0004-FigS4.pdf||application/PDF||823K||Fig. S4 EGR-1:GFP protein increases with age by immunofluorescence staining.|
|acel12179-sup-0005-FigS5.pdf||application/PDF||327K||Fig. S5 EGR-1 expression is not induced in response to stress.|
|acel12179-sup-0006-FigS6.pdf||application/PDF||209K||Fig. S6 RNAi controls.|
|acel12179-sup-0007-FigS7.pdf||application/PDF||338K||Fig. S7 Changes in H3K9 acetylation by knockdown or overexpression of egr-1, and during aging.|
Table S1 Additional lifespan data.
Table S2 Additional stress resistance data.
Table S3 Strains used in this study.
Please note: Wiley Blackwell is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.