Reductions in serum IGF-1 during aging impair health span
Article first published online: 30 DEC 2013
© 2013 The Authors. Aging Cell published by the Anatomical Society and John Wiley & Sons Ltd.
This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
Volume 13, Issue 3, pages 408–418, June 2014
How to Cite
Gong, Z., Kennedy, O., Sun, H., Wu, Y., Williams, G. A., Klein, L., Cardoso, L., Matheny, R. W., Hubbard, G. B., Ikeno, Y., Farrar, R. P., Schaffler, M. B., Adamo, M. L., Muzumdar, R. H. and Yakar, S. (2014), Reductions in serum IGF-1 during aging impair health span. Aging Cell, 13: 408–418. doi: 10.1111/acel.12188
All authors concur with the submission. The material submitted for publication has not been previously reported and is not under consideration for publication elsewhere.
- Issue published online: 23 MAY 2014
- Article first published online: 30 DEC 2013
- Accepted manuscript online: 17 DEC 2013 05:55AM EST
- Manuscript Accepted: 14 NOV 2013
- NIH/NIAMS. Grant Numbers: AR054919, AR055141
- UTHSCSA PREF
- IGF1/Insulin Signaling in Aging – Project 1 (MLA). Grant Number: AG13319
- Glenn Foundation for Medical Research
Methods S1 Reductions in serum IGF-1 during aging impair health span.
Table S1 Support information of survival studies with the congenital LID mouse cohort.
Table S2 Body and organ weights of a subcohort of control and LID mice dissected at 19-20 months of age.
Table S3 Body and organ weights of 2 year-old control and iLID mice.
Table S4 Cytokine levels in serum assessed by Mouse pro-inflammatory 7-plex ultra-sensitive kit.
Table S5 Tumor incidence in control and iLID mice.
Table S6 Primers used for gene expression studies using real-time PCR.
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