Weekly administration of rapamycin improves survival and biomarkers in obese male mice on high-fat diet
Article first published online: 22 MAR 2014
© 2014 The Authors. Aging Cell published by the Anatomical Society and John Wiley & Sons Ltd.
This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
Volume 13, Issue 4, pages 616–622, August 2014
How to Cite
Leontieva, O. V., Paszkiewicz, G. M. and Blagosklonny, M. V. (2014), Weekly administration of rapamycin improves survival and biomarkers in obese male mice on high-fat diet. Aging Cell, 13: 616–622. doi: 10.1111/acel.12211
- Issue published online: 29 JUL 2014
- Article first published online: 22 MAR 2014
- Manuscript Accepted: 2 FEB 2014
|acel12211-sup-0001-FigS1.jpg||image/jpg||890K||Fig. S1 Percent of initial body weight.|
|acel12211-sup-0002-FigS2.jpg||image/jpg||851K||Fig. S2 Kaplan–Meier survival curves for control mice on HF diet (HF, n = 10) and mice treated with schedule R1 (n = 10) and R3 (n = 9).|
|acel12211-sup-0003-FigS3.jpg||image/jpg||622K||Fig. S3 Commassie Blue-stained membrane of liver blots shown in Figure 4A to confirm equal loading.|
|acel12211-sup-0004-FigS4.jpg||image/jpg||984K||Fig. S4 Levels of p-S6 and p-AKT in kidneys of surviving mice.|
|acel12211-sup-0005-FigS5.jpg||image/jpg||1058K||Fig. S5 Levels of fasted and nonfasted glucose and insulin in blood plasma of male mice.|
|acel12211-sup-0006-FigS6.jpg||image/jpg||803K||Fig. S6 Correlation between metabolic parameters in fasted plasma.|
|acel12211-sup-0007-FigS7.jpg||image/jpg||875K||Fig. S7 Kaplan–Meier survival curves.|
|acel12211-sup-0008-TableS1.xls||application/msexcel||14K||Table S1 Survival curve high-fat control (HF) and high fat + rapamycin-treated group 2 (HF+rapamycin (group 2)).|
|acel12211-sup-0009-TableS2.xls||application/msexcel||16K||Table S2 Survival curve high-fat control (HF) and high fat + rapamycin-treated groups (HF+rapamycin all groups).|
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