Alteration in the Wnt microenvironment directly regulates molecular events leading to pulmonary senescence
Article first published online: 1 JUL 2014
© 2014 The Authors. Aging Cell published by the Anatomical Society and John Wiley & Sons Ltd.
This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
Volume 13, Issue 5, pages 838–849, October 2014
How to Cite
Kovacs, T., Csongei, V., Feller, D., Ernszt, D., Smuk, G., Sarosi, V., Jakab, L., Kvell, K., Bartis, D. and Pongracz, J. E. (2014), Alteration in the Wnt microenvironment directly regulates molecular events leading to pulmonary senescence. Aging Cell, 13: 838–849. doi: 10.1111/acel.12240
- Issue published online: 19 SEP 2014
- Article first published online: 1 JUL 2014
- Manuscript Accepted: 22 MAY 2014
- European Union and the State of Hungary
- European Social Fund . Grant Number: TÁMOP-4.2.4.A/ 2-11/1-2012-0001
- National Excellence Program
Fig. S1 The structure of the lung during aging presented by SkyScan micro Computed Tomograph; photographs of lungs of (A): 1–month-old and (B): 24-month-old Balb/c mice were obtained in 180 degree and converted to 3D by CTVol software (Skyscan).
Fig. S2 Characterization of 3D lung micro-tissue model.
Fig. S3 Inflammatory cytokines in 2D vs 3D tissues.
Fig S4 Pro-surfactant protein C expression following rhWnt5a treatment of the 3D human lung tissue model.
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