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acel12255-sup-0001-TableS1-S3.docxWord document21K

Table S1 LD50 values of dermal fibroblasts isolated from WT and Irs1−/− mice exposed to lethal oxidative and non-oxidative stressors; cultured at 3% and 21% O2.

Table S2 LD50 values of myoblasts isolated from WT and Irs1−/− mice exposed to lethal oxidative stressors; cultured at 3% O2.

Table S3 Primers used in the present study.

acel12255-sup-0002-FigureS1-S2.docxWord document390K

Fig. S1 Fibroblasts from Irs1−/− mice are not more resistant to lethal stress than fibroblasts from WT mice at 3% O2.

Fig. S2 Fibroblasts from Irs1−/− mice do not differ in terms of (A) proliferation rates, (B) cell cycle progression or (C) growth rates after 24 h or 48 h of culture (21% O2) compared with cells derived from WT mice (n = 4 per group).

acel12255-sup-0003-methods.pdfapplication/PDF100KData S1 Experimental Procedures.

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