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Aging Cell

Cover image for Vol. 11 Issue 5

October 2012

Volume 11, Issue 5

Pages 727–919

  1. Review

    1. Top of page
    2. Review
    3. Original Articles
    4. Short Takes
    5. Announcement
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      Review: a meta-analysis of GWAS and age-associated diseases (pages 727–731)

      William R. Jeck, Alex P. Siebold and Norman E. Sharpless

      Version of Record online: 30 AUG 2012 | DOI: 10.1111/j.1474-9726.2012.00871.x

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  2. Original Articles

    1. Top of page
    2. Review
    3. Original Articles
    4. Short Takes
    5. Announcement
    1. You have full text access to this Open Access content
      The aged microenvironment contributes to the age-related functional defects of CD4 T cells in mice (pages 732–740)

      Julie S. Lefebvre, Alexander C. Maue, Sheri M. Eaton, Paula A. Lanthier, Michael Tighe and Laura Haynes

      Version of Record online: 11 JUN 2012 | DOI: 10.1111/j.1474-9726.2012.00836.x

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      Temporal analysis of vascular smooth muscle cell elasticity and adhesion reveals oscillation waveforms that differ with aging (pages 741–750)

      Yi Zhu, Hongyu Qiu, Jerome P. Trzeciakowski, Zhe Sun, Zhaohui Li, Zhongkui Hong, Michael A. Hill, William C. Hunter, Dorothy E. Vatner, Stephen F. Vatner and Gerald A. Meininger

      Version of Record online: 26 JUN 2012 | DOI: 10.1111/j.1474-9726.2012.00840.x

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      Age-dependent vulnerability to experimental acute pancreatitis is associated with increased systemic inflammation and thrombosis (pages 760–769)

      Daiki Okamura, Marlene E. Starr, Eun Y. Lee, Arnold J. Stromberg, B. Mark Evers and Hiroshi Saito

      Version of Record online: 4 JUL 2012 | DOI: 10.1111/j.1474-9726.2012.00841.x

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      Dietary restriction attenuates age-associated muscle atrophy by lowering oxidative stress in mice even in complete absence of CuZnSOD (pages 770–782)

      Young C. Jang, Yuhong Liu, Christopher R. Hayworth, Arunabh Bhattacharya, Michael S. Lustgarten, Florian L. Muller, Asish Chaudhuri, Wenbo Qi, Yan Li, Jing-Yi Huang, Eric Verdin, Arlan Richardson and Holly Van Remmen

      Version of Record online: 2 AUG 2012 | DOI: 10.1111/j.1474-9726.2012.00843.x

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      Nutrient-dependent requirement for SOD1 in lifespan extension by protein restriction in Drosophila melanogaster (pages 783–793)

      Xiaoping Sun, Toshimitsu Komatsu, Jinhwan Lim, Mara Laslo, Jason Yolitz, Cecilia Wang, Luc Poirier, Thomas Alberico and Sige Zou

      Version of Record online: 3 JUL 2012 | DOI: 10.1111/j.1474-9726.2012.00842.x

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      Deviation of innate circadian period from 24 h reduces longevity in mice (pages 794–800)

      Sergiy Libert, Michael S. Bonkowski, Kelli Pointer, Scott D. Pletcher and Leonard Guarente

      Version of Record online: 12 JUL 2012 | DOI: 10.1111/j.1474-9726.2012.00846.x

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      The impact of aging on mitochondrial function and biogenesis pathways in skeletal muscle of sedentary high- and low-functioning elderly individuals (pages 801–809)

      Anna-Maria Joseph, Peter J. Adhihetty, Thomas W. Buford, Stephanie E. Wohlgemuth, Hazel A. Lees, Linda M.-D. Nguyen, Juan M. Aranda, Bhanu D. Sandesara, Marco Pahor, Todd M. Manini, Emanuele Marzetti and Christiaan Leeuwenburgh

      Version of Record online: 9 JUL 2012 | DOI: 10.1111/j.1474-9726.2012.00844.x

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      Endoplasmic reticulum stress occurs downstream of GluN2B subunit of N-methyl-D-aspartate receptor in mature hippocampal cultures treated with amyloid-β oligomers (pages 823–833)

      Rui O. Costa, Pascale N. Lacor, Ildete L. Ferreira, Rosa Resende, Yves P. Auberson, William L. Klein, Catarina R. Oliveira, Ana C. Rego and Cláudia M. F. Pereira

      Version of Record online: 15 JUL 2012 | DOI: 10.1111/j.1474-9726.2012.00848.x

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      Aβ1-42-mediated down-regulation of Uch-L1 is dependent on NF-κB activation and impaired BACE1 lysosomal degradation (pages 834–844)

      Michela Guglielmotto, Debora Monteleone, Marina Boido, Antonio Piras, Luca Giliberto, Roberta Borghi, Alessandro Vercelli, Michele Fornaro, Massimo Tabaton and Elena Tamagno

      Version of Record online: 1 AUG 2012 | DOI: 10.1111/j.1474-9726.2012.00854.x

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    13. You have full text access to this OnlineOpen article
      Glucose delays age-dependent proteotoxicity (pages 856–866)

      Arnaud Tauffenberger, Alexandra Vaccaro, Anais Aulas, Christine Vande Velde and J. Alex Parker

      Version of Record online: 1 AUG 2012 | DOI: 10.1111/j.1474-9726.2012.00855.x

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      Aging is associated with chronic innate immune activation and dysregulation of monocyte phenotype and function (pages 867–875)

      Anna C. Hearps, Genevieve E. Martin, Thomas A. Angelovich, Wan-Jung Cheng, Anna Maisa, Alan L. Landay, Anthony Jaworowski and Suzanne M. Crowe

      Version of Record online: 20 JUL 2012 | DOI: 10.1111/j.1474-9726.2012.00851.x

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      Dehydroepiandrosterone replacement therapy in older adults improves indices of arterial stiffness (pages 876–884)

      Edward P. Weiss, Dennis T. Villareal, Ali A. Ehsani, Luigi Fontana and John O. Holloszy

      Version of Record online: 1 AUG 2012 | DOI: 10.1111/j.1474-9726.2012.00852.x

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      Ca2+ dysregulation in neurons from transgenic mice expressing mutant presenilin 2 (pages 885–893)

      Maulilio J. Kipanyula, Laura Contreras, Enrico Zampese, Cristian Lazzari, Andrea K. C. Wong, Paola Pizzo, Cristina Fasolato and Tullio Pozzan

      Version of Record online: 6 AUG 2012 | DOI: 10.1111/j.1474-9726.2012.00858.x

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      Accelerated aging-related transcriptome changes in the female prefrontal cortex (pages 894–901)

      Yuan Yuan, Yi-Ping Phoebe Chen, Jerome Boyd-Kirkup, Philipp Khaitovich and Mehmet Somel

      Version of Record online: 2 AUG 2012 | DOI: 10.1111/j.1474-9726.2012.00859.x

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      SnoN activates p53 directly to regulate aging and tumorigenesis (pages 902–911)

      Deng Pan, Qingwei Zhu, Michael J. Conboy, Irina M. Conboy and Kunxin Luo

      Version of Record online: 27 AUG 2012 | DOI: 10.1111/j.1474-9726.2012.00857.x

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  3. Short Takes

    1. Top of page
    2. Review
    3. Original Articles
    4. Short Takes
    5. Announcement
    1. You have full text access to this Open Access content
      The age-related increase in low-grade systemic inflammation (Inflammaging) is not driven by cytomegalovirus infection (pages 912–915)

      David B. Bartlett, Charlotte M. Firth, Anna C. Phillips, Paul Moss, Daniel Baylis, Holly Syddall, Avan A. Sayer, Cyrus Cooper and Janet M. Lord

      Version of Record online: 12 JUL 2012 | DOI: 10.1111/j.1474-9726.2012.00849.x

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      Expression of p16INK4a as a biomarker of T-cell aging in HIV-infected patients prior to and during antiretroviral therapy (pages 916–918)

      Julie A. E. Nelson, Janakiraman Krishnamurthy, Prema Menezes, Yan Liu, Michael G. Hudgens, Norman E. Sharpless and Joseph J. Eron Jr

      Version of Record online: 19 JUL 2012 | DOI: 10.1111/j.1474-9726.2012.00856.x

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  4. Announcement

    1. Top of page
    2. Review
    3. Original Articles
    4. Short Takes
    5. Announcement
    1. You have full text access to this Open Access content

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