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Aging Cell

Cover image for Aging Cell

June 2013

Volume 12, Issue 3

Pages 333–531

  1. Original Articles

    1. Top of page
    2. Original Articles
    3. Short Take
    4. Commentary
    5. Review
    6. Announcement
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      Targeting macrophages rescues age-related immune deficiencies in C57BL/6J geriatric mice (pages 345–357)

      Connie Jackaman, Hannah G. Radley-Crabb, Zoe Soffe, Tea Shavlakadze, Miranda D. Grounds and Delia J. Nelson

      Article first published online: 27 MAR 2013 | DOI: 10.1111/acel.12062

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      β-amyloid context intensifies vascular smooth muscle cells induced inflammatory response and de-differentiation (pages 358–369)

      Amélie Vromman, Nesrine Trabelsi, Clotilde Rouxel, Gilbert Béréziat, Isabelle Limon and Régis Blaise

      Article first published online: 1 APR 2013 | DOI: 10.1111/acel.12056

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      mTOR regulates tau phosphorylation and degradation: implications for Alzheimer's disease and other tauopathies (pages 370–380)

      Antonella Caccamo, Andrea Magrì, David X. Medina, Elena V. Wisely, Manuel F. López-Aranda, Alcino J. Silva and Salvatore Oddo

      Article first published online: 24 MAR 2013 | DOI: 10.1111/acel.12057

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      Cytomegalovirus infection is associated with increased mortality in the older population (pages 381–387)

      George M. Savva, Annette Pachnio, Baksho Kaul, Kevin Morgan, Felicia A. Huppert, Carol Brayne and Paul A. H. Moss, The Medical Research Council Cognitive Function and Ageing Study

      Article first published online: 19 APR 2013 | DOI: 10.1111/acel.12059

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      WormFarm: a quantitative control and measurement device toward automated Caenorhabditis elegans aging analysis (pages 398–409)

      Bo Xian, Jie Shen, Weiyang Chen, Na Sun, Nan Qiao, Dongqing Jiang, Tao Yu, Yongfan Men, Zhijun Han, Yuhong Pang, Matt Kaeberlein, Yanyi Huang and Jing-Dong J. Han

      Article first published online: 27 MAR 2013 | DOI: 10.1111/acel.12063

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      Impaired mitochondrial fatty acid oxidation and insulin resistance in aging: novel protective role of glutathione (pages 415–425)

      Dan Nguyen, Susan L. Samson, Vasumathi T. Reddy, Erica V. Gonzalez and Rajagopal V. Sekhar

      Article first published online: 19 APR 2013 | DOI: 10.1111/acel.12073

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      Lipidomics of familial longevity (pages 426–434)

      Vanessa Gonzalez-Covarrubias, Marian Beekman, Hae-Won Uh, Adrie Dane, Jorne Troost, Iryna Paliukhovich, Frans M. van der Kloet, Jeanine Houwing-Duistermaat, Rob J. Vreeken, Thomas Hankemeier and Eline P. Slagboom

      Article first published online: 1 APR 2013 | DOI: 10.1111/acel.12064

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      Oxidative stress activates a specific p53 transcriptional response that regulates cellular senescence and aging (pages 435–445)

      Valentina Gambino, Giulia De Michele, Oriella Venezia, Pierluigi Migliaccio, Valentina Dall'Olio, Loris Bernard, Simone Paolo Minardi, Maria Agnese Della Fazia, Daniela Bartoli, Giuseppe Servillo, Myriam Alcalay, Lucilla Luzi, Marco Giorgio, Heidi Scrable, Pier Giuseppe Pelicci and Enrica Migliaccio

      Article first published online: 27 MAR 2013 | DOI: 10.1111/acel.12060

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      High levels of oncomiR-21 contribute to the senescence-induced growth arrest in normal human cells and its knock-down increases the replicative lifespan (pages 446–458)

      Hanna Dellago, Barbara Preschitz-Kammerhofer, Lucia Terlecki-Zaniewicz, Carina Schreiner, Klaus Fortschegger, Martina W.-F. Chang, Matthias Hackl, Rossella Monteforte, Harald Kühnel, Markus Schosserer, Florian Gruber, Erwin Tschachler, Marcel Scheideler, Regina Grillari-Voglauer, Johannes Grillari and Matthias Wieser

      Article first published online: 19 APR 2013 | DOI: 10.1111/acel.12069

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      Identification of a metabolic signature for multidimensional impairment and mortality risk in hospitalized older patients (pages 459–466)

      Luigi Fontana, Filomena Addante, Massimiliano Copetti, Giulia Paroni, Andrea Fontana, Daniele Sancarlo, Fabio Pellegrini, Luigi Ferrucci and Alberto Pilotto

      Article first published online: 10 APR 2013 | DOI: 10.1111/acel.12068

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      DNA damage in normally and prematurely aged mice (pages 467–477)

      Alexander Y. Maslov, Shireen Ganapathi, Maaike Westerhof, Wilber Quispe-Tintaya, Ryan R. White, Bennett Van Houten, Erwin Reiling, Martijn E. T. Dollé, Harry van Steeg, Paul Hasty, Jan H. J. Hoeijmakers and Jan Vijg

      Article first published online: 24 APR 2013 | DOI: 10.1111/acel.12071

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      Balance between autophagic pathways preserves retinal homeostasis (pages 478–488)

      Natalia Rodríguez-Muela, Hiroshi Koga, Lucía García-Ledo, Pedro de la Villa, Enrique J. de la Rosa, Ana María Cuervo and Patricia Boya

      Article first published online: 19 APR 2013 | DOI: 10.1111/acel.12072

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      Metformin inhibits the senescence-associated secretory phenotype by interfering with IKK/NF-κB activation (pages 489–498)

      Olga Moiseeva, Xavier Deschênes-Simard, Emmanuelle St-Germain, Sebastian Igelmann, Geneviève Huot, Alexandra E. Cadar, Véronique Bourdeau, Michael N. Pollak and Gerardo Ferbeyre

      Article first published online: 23 APR 2013 | DOI: 10.1111/acel.12075

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      Reduced amyloid-β degradation in early Alzheimer's disease but not in the APPswePS1dE9 and 3xTg-AD mouse models (pages 499–507)

      Anita Stargardt, Judith Gillis, Willem Kamphuis, Anne Wiemhoefer, Lieneke Kooijman, Marcel Raspe, Willemien Benckhuijsen, Jan W. Drijfhout, Elly M. Hol and Eric Reits

      Article first published online: 23 APR 2013 | DOI: 10.1111/acel.12074

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      Mitochondrial hormesis links low-dose arsenite exposure to lifespan extension (pages 508–517)

      Sebastian Schmeisser, Kathrin Schmeisser, Sandra Weimer, Marco Groth, Steffen Priebe, Eugen Fazius, Doreen Kuhlow, Denis Pick, Jürgen W. Einax, Reinhard Guthke, Matthias Platzer, Kim Zarse and Michael Ristow

      Article first published online: 6 MAY 2013 | DOI: 10.1111/acel.12076

  2. Short Take

    1. Top of page
    2. Original Articles
    3. Short Take
    4. Commentary
    5. Review
    6. Announcement
    1. You have full text access to this OnlineOpen article
      FOXO4 is necessary for neural differentiation of human embryonic stem cells (pages 518–522)

      David Vilchez, Leah Boyer, Margaret Lutz, Carsten Merkwirth, Ianessa Morantte, Chris Tse, Brian Spencer, Lesley Page, Eliezer Masliah, William Travis Berggren, Fred H. Gage and Andrew Dillin

      Article first published online: 10 APR 2013 | DOI: 10.1111/acel.12067

  3. Commentary

    1. Top of page
    2. Original Articles
    3. Short Take
    4. Commentary
    5. Review
    6. Announcement
    1. You have full text access to this Open Access content
  4. Review

    1. Top of page
    2. Original Articles
    3. Short Take
    4. Commentary
    5. Review
    6. Announcement
    1. You have full text access to this Open Access content
  5. Announcement

    1. Top of page
    2. Original Articles
    3. Short Take
    4. Commentary
    5. Review
    6. Announcement
    1. You have full text access to this Open Access content

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