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Data S1. Materials and methods.

Data S2. Results.

Fig. S1. Effect of i.p. injections of 600 mg/kg NaB on global nuclear HDAC activity.

Fig. S2. Parametric analysis of EIBS.

Fig. S3. Effect of 600 mg/kg NaB on 0.5 g/kg-EIBS.

Fig. S4. Effects of chronic 1.0 or 2.0 g/kg-EIBS in the absence or presence of 600 mg/kg NaB on blood EtOH and estrogens concentrations.

Fig. S5. Effects of chronic 1.0 g/kg or 2.0 g/kg EtOH in the absence or presence of 600 mg/kg NaB on gene expression.

Table S1. EtOH 1.0 g/kg and genes involved in transduction pathways: functional classifications of genes regulated by acute treatment and EIBS in the absence or presence of 600 mg/kg NaB.

Table S2. EtOH 2.0 g/kg and genes involved in transduction pathways: functional classifications of genes regulated by acute treatment and EIBS in the absence or presence of 600 mg/kg NaB.

Table S3. EtOH 1.0 g/kg and genes involved in epigenetic mechanisms: functional classifications of genes regulated by acute treatment and EIBS in the absence or presence of 600 mg/kg NaB.

Table S4. EtOH 2.0 g/kg and genes involved in epigenetic mechanisms: functional classifications of genes regulated by acute treatment and EIBS in the absence or presence of 600 mg/kg NaB.

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