Gender Differences in Lifetime Alcohol Dependence: Results from the National Epidemiologic Survey on Alcohol and Related Conditions
Article first published online: 13 JUN 2013
Copyright © 2013 by the Research Society on Alcoholism
Alcoholism: Clinical and Experimental Research
Volume 37, Issue 10, pages 1696–1705, October 2013
How to Cite
Khan, S., Okuda, M., Hasin, D. S., Secades-Villa, R., Keyes, K., Lin, K.-H., Grant, B. and Blanco, C. (2013), Gender Differences in Lifetime Alcohol Dependence: Results from the National Epidemiologic Survey on Alcohol and Related Conditions. Alcoholism: Clinical and Experimental Research, 37: 1696–1705. doi: 10.1111/acer.12158
- Issue published online: 3 OCT 2013
- Article first published online: 13 JUN 2013
- Manuscript Accepted: 7 FEB 2013
- Manuscript Received: 24 JUL 2012
- NIH. Grant Numbers: DA019606-S3, AA014223 , AA018111, DA020783-S4, DA019606, DA020783, DA023200, DA023973, MH076051, MH082773 , CA133050
- American Foundation for Suicide Prevention
- Spanish Ministry of Education. Grant Number: PR2010-0501
- NESARC ;
- Alcohol Dependence;
- Gender Differences;
An extensive clinical literature has noted gender differences in the etiology and clinical characteristics of individuals with alcohol dependence (AD). Despite this knowledge, many important questions remain.
Using the 2001 to 2002 National Epidemiologic Survey on Alcohol and Related Conditions (n = 43,093), we examined differences in sociodemographic characteristics, psychiatric and medical comorbidities, clinical correlates, risk factors, and treatment-utilization patterns of men (N = 2,974) and women (N = 1,807) with lifetime AD.
Men with lifetime AD were more likely than women to be diagnosed with any substance use disorder and antisocial personality disorder, whereas women were more likely to have mood and anxiety disorders. After adjusting for sociodemographic characteristics and gender differences in psychiatric comorbidity in the general population, AD was associated with externalizing disorders and any mood disorder among women only. Men with AD met more criteria, had longer episodes, and were younger at the age of first drink. There were no gender differences in remission rates. Women with AD were more likely to have a family and a spouse with history of alcohol use disorders. Treatment rates were low for both genders, and women were more likely to report social stigmatization as a treatment barrier.
There are important gender differences in the psychiatric comorbidities, risk factors, clinical characteristics, and treatment-utilization patterns among individuals with lifetime AD.