Differential Striatal Dopamine Responses Following Oral Alcohol in Individuals at Varying Risk for Dependence
Article first published online: 6 AUG 2013
Copyright © 2013 by the Research Society on Alcoholism
Alcoholism: Clinical and Experimental Research
Volume 38, Issue 1, pages 126–134, January 2014
How to Cite
Setiawan, E., Pihl, R. O., Dagher, A., Schlagintweit, H., Casey, K. F., Benkelfat, C. and Leyton, M. (2014), Differential Striatal Dopamine Responses Following Oral Alcohol in Individuals at Varying Risk for Dependence. Alcoholism: Clinical and Experimental Research, 38: 126–134. doi: 10.1111/acer.12218
- Issue published online: 21 JAN 2014
- Article first published online: 6 AUG 2013
- Manuscript Accepted: 15 MAY 2013
- Manuscript Received: 16 OCT 2012
- Canadian Institutes of Health Research. Grant Number: CIHR MOP-64426
- CIHR and McGill University
- McGill University
Data S1. Materials and Methods.
Data S2. Results.
Table S1. Demographics by Personality Sensation Seeking-Sensitivity to Reward Risk Group.
|acer12218-sup-0002-FigS1.pdf||application/PDF||672K||Fig. S1. Significant clusters from voxelwise analysis of BPND in the placebo compared to the alcohol scan. (a) High-risk personality group where BPND Alc was significantly decreased compared to BPND Pbo, X = −8.5, Y = 6, Z = −6, t-map threshold at t ≥ 3.1, p < 0.05, corrected for multiple comparisons. (b) Low-risk personality group where BPND Alc was significantly increased compared to BPND Pbo, X = 17, Y = 18, Z = 6, t-map threshold at t ≤ −3.1, p < 0.05, corrected for multiple comparisons.|
|acer12218-sup-0003-FigS2.pdf||application/PDF||374K||Fig. S2. BPND values from significant clusters in (a) high-risk personality, n = 14; and (b) low-risk personality Individuals, n = 12. *Significant from placebo, p ≤ 0.05, Bonferroni corrected. Error bars represent SEM.|
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