Clinical and sociodemographic comparison of people at high-risk for psychosis and with first-episode psychosis
Article first published online: 20 AUG 2012
© 2012 John Wiley & Sons A/S
Acta Psychiatrica Scandinavica
Volume 127, Issue 3, pages 210–216, March 2013
How to Cite
Zimbrón, J., Ruiz de Azúa, S., Khandaker, G. M., Gandamaneni, P. K., Crane, C. M., González-Pinto, A., Stochl, J., Jones, P. B. and Pérez, J. (2013), Clinical and sociodemographic comparison of people at high-risk for psychosis and with first-episode psychosis. Acta Psychiatrica Scandinavica, 127: 210–216. doi: 10.1111/acps.12000
- Issue published online: 8 FEB 2013
- Article first published online: 20 AUG 2012
- Accepted for publication July 9, 2012
- psychotic disorder;
- early intervention
Zimbrón J, Ruiz de Azúa S, Khandaker GM, Gandamaneni PK, Crane CM, González-Pinto A, Stochl J, Jones PB, Pérez J. Clinical and sociodemographic comparison of people at high-risk for psychosis and with first-episode psychosis.
Objective: To compare clinical and sociodemographic characteristics previously associated with psychosis, between individuals at high-risk for psychosis (HR) and patients experiencing a first episode psychosis (FEP), to achieve a better understanding of factors associated with psychosis.
Method: Cross-sectional comparison of 30 individuals at HR with 30 age-gender matched FEP, presenting to an early intervention service for psychosis. Participants were followed-up for 2 years to establish the proportion of HR who made the transition into FEP.
Results: Both groups showed similar socio-clinical characteristics, including immigration status, employment history, marital status, family history of psychotic illness, self-harm and alcohol and drug use. The HR group had a lower level of education, higher burden of trauma, earlier onset of psychiatric symptoms and a longer delay in accessing specialised services. A younger onset of symptoms was associated with a longer delay in accessing services in both groups. After a 2 year follow-up, only three (10%) of the HR group made a transition into FEP.
Conclusion: The similarities observed between individuals at HR and those with FEP suggest that known variables associated with psychosis may be equally prevalent in people at HR who do not develop a psychotic disorder.