Antidepressants and the risk of suicide in young persons – prescription trends and toxicological analyses
Article first published online: 17 JUN 2013
© 2013 The Authors. Acta Psychiatrica Scandinavica published by John Wiley & Sons Ltd.
This is an open access article under the terms of the Creative Commons Attribution-NonCommercial License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.
Acta Psychiatrica Scandinavica
How to Cite
Antidepressants and the risk of suicide in young persons – prescription trends and toxicological analyses., .
- Article first published online: 17 JUN 2013
- Manuscript Accepted: 13 MAY 2013
- forensic toxicology
To assess trends in the use of antidepressants among young suicides after the warning that these drugs might increase the risk of suicide.
Individual data of all 845 suicides in the 10- to 19-year age group in Sweden in the time period 1992–2003 (baseline), and in 2004–2010 (after the warning). Outcome data are prescriptions of antidepressants prior to death and detections of antidepressants in post-mortem toxicology.
After the warning, suicide in this age group increased for five consecutive years (60.5%). The increase occurred among individuals not treated with antidepressants.
This study provides further support for the hypothesis that the warning, contrary to its intention, may have increased young suicides by leaving a number of suicidal young persons without treatment with antidepressants.