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A randomized controlled trial of a smoking cessation intervention conducted among prisoners
Article first published online: 11 MAR 2013
© 2012 The Authors, Addiction © 2012 Society for the Study of Addiction
Volume 108, Issue 5, pages 966–974, May 2013
How to Cite
Richmond, R., Indig, D., Butler, T., Wilhelm, K., Archer, V. and Wodak, A. (2013), A randomized controlled trial of a smoking cessation intervention conducted among prisoners. Addiction, 108: 966–974. doi: 10.1111/add.12084
- Issue published online: 15 APR 2013
- Article first published online: 11 MAR 2013
- Accepted manuscript online: 11 DEC 2012 06:15AM EST
- Manuscript Accepted: 3 DEC 2012
- Manuscript Revised: 1 FEB 2012
- Manuscript Received: 12 NOV 2011
- National Health and Medical Research Council. Grant Number: 350829
- NSW Department of Health
- Queensland Department of Health
- Cognitive therapy;
- nicotine dependence;
- nicotine patch;
- smoking cessation
To evaluate the efficacy of nortriptyline (NOR) added to a multi-component smoking cessation intervention, which included cognitive–behavioural therapy (CBT) and provision of nicotine replacement therapy (NRT).
Randomized controlled trial (RCT) comparing two study groups with blinded follow-up at 3, 6 and 12 months. Both groups received a multi-component smoking cessation intervention comprising two half-hour individual sessions of CBT and NRT with either active NOR or placebo.
Prisons in New South Wales (17) and Queensland (one), Australia.
A total of 425 male prisoners met inclusion criteria and were allocated to either treatment (n = 206) or control group (n = 219).
Primary end-points at 3, 6 and 12 months were continuous abstinence, point prevalence abstinence and reporting a 50% reduction in smoking. Smoking status was confirmed by expired carbon monoxide, using a cut-point of ≤10 parts per million.
Participants' demographics and baseline tobacco use were similar in treatment and control groups. Based on an intention-to-treat analysis, continuous abstinence between the treatment and control groups was not significantly different at 3 months (23.8 versus 16.4%), 6 months (17.5 versus 12.3%) and 12 months (11.7 versus 11.9%).
Adding nortriptyline to a smoking cessation treatment package consisting of behavioural support and nicotine replacement therapy does not appear to improve long-term abstinence rates in male prisoners.