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Supplement S1 EM steps for disaggregating pooled genotypes under scenarios with genotyping errors.

Supplement S2 Modified Lee's method.

Supplement S3 Results based on an alternative parameterization of the error matrix.

Figure S3.1 Noncentrality parameter and power for tests of offspring inherited genetic effects in the absence of genotyping errors.

Figure S3.2 Noncentrality parameter and power for tests of offspring inherited genetic effects in the presence of genotyping errors.

Supplement S4. Table S4 Simulation results (estimates, 95% confidence limits, and power) for homogeneous populations.

Supplement S5. Table S5 Simulation results (estimates, 95% confidence limits, and power) for stratified populations.

Supplement S6. Figure S6 Power as a function of relative risk.

Supplement S7 Noncentrality parameter calculation using an incorrect error matrix.

Table S7.1 Autoregressive error matrix.

Table S7.2 Harmonic-decay error matrix.

Table S7.3 Simulation results (estimates, 95% confidence limits, and power) for data generated using an autoregressive error matrix.

Table S7.4 Simulation results (estimates, 95% confidence limits, and power) for data generated using a harmonic-decay error matrix.

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