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Keywords:

  • Chemokines;
  • decidual;
  • macrophages;
  • pregnancy;
  • T cells;
  • tolerance;
  • trophoblast

A recent study in the journal Science offers insights into the mechanism behind feto-maternal tolerance, as evidenced by changes in the immuno-logical environment of the uterus and decidua. They also provide a rich area of research for the understanding of the regulation of the immune system in other complicated medical conditions, including cancer and pregnancies affected by infection or autoimmunity.