Changes in the Fetal and Neonatal Cytokine Profile in Pregnancies Complicated by Fetal Growth Restriction
Article first published online: 24 DEC 2012
© 2012 John Wiley & Sons A/S
American Journal of Reproductive Immunology
Volume 69, Issue 5, pages 441–448, May 2013
How to Cite
Changes in the fetal and neonatal cytokine profile in pregnancies complicated by fetal growth restriction. Am J Reprod Immunol 2013; 69: 441–448., , , .
- Issue published online: 12 APR 2013
- Article first published online: 24 DEC 2012
- Manuscript Accepted: 2 NOV 2012
- Manuscript Received: 13 OCT 2012
Fetal growth restriction (FGR) is a major complication of pregnancy with unknown etiology which results in marked fetal, neonatal and long-term morbidity, and mortality. FGR is likely to result from suboptimal placental implantation and perturbed immunological interactions. The diagnostic criteria for FGR vary between studies and the condition often occurs with pre-eclampsia. Here, we review published studies of fetal and neonatal cytokines in FGR and compare these with studies of small for gestational age, pre-eclampsia and pregnancies delivering pre-term.