Pregnancy and Antiphospholipid Syndrome

Authors

  • Michael D. Lockshin

    Corresponding author
    • Department of Medicine and Obstetrics-Gynecology, Weill-Cornell Medical College, Hospital for Special Surgery New York, New York, NY, USA
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Correspondence Michael D. Lockshin, Hospital for Special Surgery, 535 E 70th Street, New York, NY 10021, USA E-mail: LockshinM@HSS.edu

Abstract

APS causes adverse pregnancy outcome, especially in younger patients with SLE or prior thromboses. LAC is the best predictor of adverse outcome. Prior conclusions on the efficacy of heparin for prevention of poor outcome may be suspect. New therapies are under evaluation in animal models but how to introduce them into the clinic is unclear.

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