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ajt12368-sm-0001-SupFig.pdf56KFigure S1: Lung function was measured in wild-type (WT), RAGE-/- and Jα18-/- mice after sham surgery with or without recombinant HMGB1 (rH) treatment. (A–C) No change in airway resistance, pulmonary compliance or pulmonary artery pressure occurred between sham WT, RAGE-/- or Jα18-/- mice with or without recombinant HMGB1 treatment. (D) A significant increase in IL-17 production in BAL fluid occurred in WT sham mice after recombinant HMGB1 treatment compared to WT sham alone. However, there was no difference in IL-17 production between sham RAGE-/- or sham Jα18-/- mice with or without recombinant HMGB1 treatment *P< 0.05 versus WT Sham; n = 5/group.
ajt12368-sm-0001-SuppLaubach.docx36KSupplemental Materials and Methods

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