Individualized Mycophenolate Mofetil Dosing Based on Drug Exposure Significantly Improves Patient Outcomes After Renal Transplantation (pages 2496–2503)
Y. Le Meur, M. Büchler, A. Thierry, S. Caillard, F. Villemain, S. Lavaud, I. Etienne, P.-F. Westeel, B. H. De Ligny, L. Rostaing, E. Thervet, J. C. Szelag, J.-P. Rérolle, A. Rousseau, G. Touchard and P. Marquet
Article first published online: 9 OCT 2007 | DOI: 10.1111/j.1600-6143.2007.01983.x
In this randomised trial comparing fixed dose versus therapeutic drug monitoring of MMF in kidney graft recipients, the concentration control group experienced less treatment failure and less rejection. See also editorial by West-Thielke and Kaplan in this issue on page 2441.