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American Journal of Transplantation

Cover image for Vol. 7 Issue 7

July 2007

Volume 7, Issue 7

Pages 1683–1873

  1. Special Feature

    1. Top of page
    2. Special Feature
    3. Personal Viewpoints
    4. Ethics Corner
    5. Meeting Report
    6. Original Articles Basic Science
    7. Original Articles Clinical Science
    8. Brief Communications
    9. Case Reports
    10. Book Review
    11. Erratum
    1. You have free access to this content
      A Semi-Centennial Report on the Participants Depicted in Joel Babb's Portrait, ‘The First Successful Kidney Transplantation' (pages 1683–1688)

      S. P. Desai, M. S. Desai, D. N. Wood, R. Maddi, S. Leeson and N. L. Tilney

      Version of Record online: 26 MAY 2007 | DOI: 10.1111/j.1600-6143.2007.01861.x

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      The authors have described Joel Babb's painting depicting the first successful kidney transplant between identical twins that now hangs in the Countway Library of Harvard Medical School, and traced the identity of all persons shown in the painting.

  2. Personal Viewpoints

    1. Top of page
    2. Special Feature
    3. Personal Viewpoints
    4. Ethics Corner
    5. Meeting Report
    6. Original Articles Basic Science
    7. Original Articles Clinical Science
    8. Brief Communications
    9. Case Reports
    10. Book Review
    11. Erratum
    1. You have free access to this content
      Reperfusion of the Liver Allograft with Blue Blood: Is It Still the Royal Perfusate? (pages 1689–1691)

      A. Bartlett, M. Rela and N. Heaton

      Version of Record online: 26 MAY 2007 | DOI: 10.1111/j.1600-6143.2007.01834.x

      While the standard method of liver transplantation involves initial portal venous reperfusion followed by arterial reperfusion, initial arterial reperfusion may have both hemodynamic and functional benefits.

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      The Identity of Innate Immune Activators in Organ Transplantation: Origins from Within or Exterior to the Host? (pages 1692–1694)

      D. R. Goldstein

      Version of Record online: 25 MAY 2007 | DOI: 10.1111/j.1600-6143.2007.01851.x

      In the organ injury which occurs in organ transplantation, both exogenous and endogenous signals may activate the inflammatory response in the allograft.

      Corrected by:

      Erratum

      Vol. 7, Issue 9, 2215, Version of Record online: 9 AUG 2007

  3. Ethics Corner

    1. Top of page
    2. Special Feature
    3. Personal Viewpoints
    4. Ethics Corner
    5. Meeting Report
    6. Original Articles Basic Science
    7. Original Articles Clinical Science
    8. Brief Communications
    9. Case Reports
    10. Book Review
    11. Erratum
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      In Defense of Transplantation: A Reply to Nancy Scheper-Hughes (pages 1695–1697)

      B. E. Hippen and J. S. Taylor

      Version of Record online: 19 MAY 2007 | DOI: 10.1111/j.1600-6143.2007.01840.x

      The recent Scheper-Hughes essay on the “sacrificial violence in living donor transplants” is at odds with conventional understanding of transplantation and donor-recipient relationships.

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      Checklist: Passport, Plane Ticket, Organ Transplant (pages 1698–1701)

      K. A. Bramstedt and Jun Xu

      Version of Record online: 19 MAY 2007 | DOI: 10.1111/j.1600-6143.2007.01847.x

      Active and proposed US medical insurance programs appear to be taking steps to address the problems of organ availability by facilitating or even promoting transplant tourism.

  4. Meeting Report

    1. Top of page
    2. Special Feature
    3. Personal Viewpoints
    4. Ethics Corner
    5. Meeting Report
    6. Original Articles Basic Science
    7. Original Articles Clinical Science
    8. Brief Communications
    9. Case Reports
    10. Book Review
    11. Erratum
    1. You have free access to this content
      Simultaneous Liver–Kidney Transplantation: Evaluation to Decision Making (pages 1702–1709)

      C. L. Davis, S. Feng, R. Sung, F. Wong, N. P. Goodrich, L. B. Melton, K. R. Reddy, M. K. Guidinger, A. Wilkinson and J. Lake

      Version of Record online: 26 MAY 2007 | DOI: 10.1111/j.1600-6143.2007.01856.x

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      At a recent meeting on simultaneous liver-kidney transplantation, specific concern was expressed that some patients undergoing this procedure may have reversible renal failure, or may not meet the usual MELD criteria for liver transplantation.

  5. Original Articles Basic Science

    1. Top of page
    2. Special Feature
    3. Personal Viewpoints
    4. Ethics Corner
    5. Meeting Report
    6. Original Articles Basic Science
    7. Original Articles Clinical Science
    8. Brief Communications
    9. Case Reports
    10. Book Review
    11. Erratum
    1. You have free access to this content
      Different Mechanisms Control Peripheral and Central Tolerance in Hematopoietic Chimeric Mice (pages 1710–1721)

      M. Yamazaki, T. Pearson, M. A. Brehm, D. M. Miller, J. A. Mangada, T. G. Markees, L. D. Shultz, J. P. Mordes, A. A. Rossini and D. L. Greiner

      Version of Record online: 9 JUN 2007 | DOI: 10.1111/j.1600-6143.2007.01839.x

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      Skin allograft survival in mice given bone marrow allografts to induce chimerism is abrogated by depleting regulatory T cells despite the persistence of hematopoietic chimerism, indicating that chimerism and skin graft tolerance in this model are maintained by different mechanisms.

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      Contrasting Effects of Cyclosporine and Rapamycin in De Novo Generation of Alloantigen-Specific Regulatory T Cells (pages 1722–1732)

      W. Gao, Y. Lu, B. El Essawy, M. Oukka, V. K. Kuchroo and T. B. Strom

      Version of Record online: 19 MAY 2007 | DOI: 10.1111/j.1600-6143.2007.01842.x

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      In this mouse model, using reporter mice for Foxp3, sirolimus promotes de novo conversion of alloantigen specific Treg cells, whereas cyclosporine inhibits this process.

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      Effect of Inhaled Tacrolimus on Cellular and Humoral Rejection to Prevent Posttransplant Obliterative Airway Disease (pages 1733–1742)

      S. Schrepfer, T. Deuse, H. Reichenspurner, J. Hoffmann, M. Haddad, J. Fink, M. P. Fischbein, R. C. Robbins and M. P. Pelletier

      Version of Record online: 26 MAY 2007 | DOI: 10.1111/j.1600-6143.2007.01858.x

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      Tacrolimus aerosol inhalation effectively prevents orthotopic rat tracheal allografts from acute and chronic rejection without intense systemic immunosuppression.

  6. Original Articles Clinical Science

    1. Top of page
    2. Special Feature
    3. Personal Viewpoints
    4. Ethics Corner
    5. Meeting Report
    6. Original Articles Basic Science
    7. Original Articles Clinical Science
    8. Brief Communications
    9. Case Reports
    10. Book Review
    11. Erratum
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      Transplant Glomerulopathy, Late Antibody-Mediated Rejection and the ABCD Tetrad in Kidney Allograft Biopsies for Cause (pages 1743–1752)

      B. Sis, P. M. Campbell, T. Mueller, C. Hunter, S. M. Cockfield, J. Cruz, C. Meng, D. Wishart, K. Solez and P. F. Halloran

      Version of Record online: 9 JUN 2007 | DOI: 10.1111/j.1600-6143.2007.01836.x

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      A retrospective review of all biopsies with TG in one center found that the majority (73%) had evidence of antibody-mediated injury (C4d deposition and/or circulating anti-HLA antibodies) but whether the remaining cases are a different disease or a stage in which alloantibody and C4d are undetectable is unclear.

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      First Forearm Transplantation: Outcome at 3 Years (pages 1753–1762)

      S. Schneeberger, M. Ninkovic, M. Gabl, M. Ninkovic, H. Hussl, M. Rieger, W. Loescher, B. Zelger, G. Brandacher, H. Bonatti, T. Hautz, C. Boesmueller, H. Piza-Katzer and R. Margreiter

      Version of Record online: 19 MAY 2007 | DOI: 10.1111/j.1600-6143.2007.01837.x

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      The first patient to receive a forearm transplant has a satisfactory outcome at three years with no clinical signs of rejection and improving motor function, although overall sensation remains limited.

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      Prophylactic Bisphosphonate Treatment Prevents Bone Fractures After Liver Transplantation (pages 1763–1769)

      M. Bodingbauer, T. Wekerle, B. Pakrah, P. Roschger, M. Peck-Radosavljevic, G. Silberhumer, S. Grampp, S. Rockenschaub, G. Berlakovich, R. Steininger, K. Klaushofer, R. Oberbauer and F. Mühlbacher

      Version of Record online: 19 MAY 2007 | DOI: 10.1111/j.1600-6143.2007.01844.x

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      A randomized, controlled trial of zoledronic acid after liver transplantation showed a reduction in the incidence of fractures in the treated patients, as well as reduced bone turnover.

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      A Phase I/II Randomized Open-Label Multicenter Trial of Efalizumab, a Humanized Anti-CD11a, Anti-LFA-1 in Renal Transplantation (pages 1770–1777)

      F. Vincenti, R. Mendez, M. Pescovitz, P. R. Rajagopalan, A. H. Wilkinson, K. Butt, D. Laskow, D. P. Slakey, M. I. Lorber, J. P. Garg and M. Garovoy

      Version of Record online: 9 JUN 2007 | DOI: 10.1111/j.1600-6143.2007.01845.x

      In this phase I/II trial of efalizumab (anti-LFA-1), 3 of 38 patients (8%) developed post-transplant lymphoproliferative disease, all receiving high dose efalizumab and full dose cyclosporine in this phase I/II randomized trial.

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      Perceived Transparency and Fairness of the Organ Allocation System and Willingness to Donate Organs: A National Study (pages 1778–1787)

      L. E. Boulware, M. U. Troll, N.-Y. Wang and N. R. Powe

      Version of Record online: 25 MAY 2007 | DOI: 10.1111/j.1600-6143.2007.01848.x

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      In a national study of the relationship between public perceptions of organ allocation and willingness to donate organs, subjects expressing less understanding or perceiving unfairness were less likely to support donation.

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      Graft Selection Algorithm Based on Congestion Volume for Adult Living Donor Liver Transplantation (pages 1788–1796)

      M. Asakuma, Y. Fujimoto, H. Bourquain, K. Uryuhara, M. Hayashi, N. Tanigawa, H.-O. Peitgen and K. Tanaka

      Version of Record online: 25 MAY 2007 | DOI: 10.1111/j.1600-6143.2007.01849.x

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      This prospective study on 50 consecutive LDLT cases shows validity of a graft selection algorithm proposed to select the type of right lobe graft with special reference to middle hepatic vein.

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      Outcomes of Kidneys from Donors After Cardiac Death: Implications for Allocation and Preservation (pages 1797–1807)

      J. E. Locke, D. L. Segev, D. S. Warren, F. Dominici, C. E. Simpkins and R. A. Montgomery

      Version of Record online: 25 MAY 2007 | DOI: 10.1111/j.1600-6143.2007.01852.x

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      DCD kidneys from donors under 50 years of age have equivalent graft survival and function to SCD kidneys and should not be perceived as extended criteria donors.

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      Value of Posttransplant Antibody Tests in the Evaluation of Patients with Renal Graft Dysfunction (pages 1808–1814)

      J. C. Scornik, G. Guerra, J. D. Schold, T. R. Srinivas, D. Dragun and H.-U. Meier-Kriesche

      Version of Record online: 25 MAY 2007 | DOI: 10.1111/j.1600-6143.2007.01855.x

      Testing the post-transplant HLA antibodies is critical to differentiating the diagnostic alternatives in patients with allograft dysfunction.

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      A Comparison of Long-Term Survivals of Simultaneous Pancreas–Kidney Transplant between African American and Caucasian Recipients with Basiliximab Induction Therapy (pages 1815–1821)

      R. Zhang, S. Florman, S. Devidoss, A. Zarifian, C. L. Yau, A. Paramesh, M. Killackey, B. Alper, V. Fonseca and D. Slakey

      Version of Record online: 25 MAY 2007 | DOI: 10.1111/j.1600-6143.2007.01857.x

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      Testing the post-transplant HLA antibodies is critical to differentiating the diagnostic alternatives in patients with allograft dysfunction.

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      Plasma Concentrations of Mycophenolic Acid Acyl Glucuronide Are Not Associated with Diarrhea in Renal Transplant Recipients (pages 1822–1831)

      T. Heller, T. Van Gelder, K. Budde, J. W. De Fijter, D. Kuypers, W. Arns, J. Schmidt, L. Rostaing, S. H. Powis, K. Claesson, I. A. M. MacPhee, E. Pohanka, J. Engelmayer, G. Brandhorst, M. Oellerich and V. W. Armstrong

      Version of Record online: 26 MAY 2007 | DOI: 10.1111/j.1600-6143.2007.01859.x

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      In this substudy from the FDCC trial, patients on tacrolimus/mycophenolate mofetil (MMF) had a higher incidence of diarrhea despite significantly lower plasma concentrations of the acyl glucuronide metabolite of mycophenolic acid than those patients on cyclosporine/MMF.

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      Efficacy of Anti-IL-2 Receptor Antibodies Compared to no Induction and to Antilymphocyte Antibodies in Renal Transplantation (pages 1832–1842)

      V. Patlolla, X. Zhong, G. W. Reed and D. A. Mandelbrot

      Version of Record online: 9 JUN 2007 | DOI: 10.1111/j.1600-6143.2007.01860.x

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      In renal transplants, IL2R antibodies are associated with lower rejection rates and higher graft survival than no induction, and compared to depleting antilymphocyte antibodies, IL2R antibodies are associated with more rejection but no difference in graft survival.

  7. Brief Communications

    1. Top of page
    2. Special Feature
    3. Personal Viewpoints
    4. Ethics Corner
    5. Meeting Report
    6. Original Articles Basic Science
    7. Original Articles Clinical Science
    8. Brief Communications
    9. Case Reports
    10. Book Review
    11. Erratum
    1. You have free access to this content
      The Relationship of Anti-MICA Antibodies and MICA Expression with Heart Allograft Rejection (pages 1842–1848)

      B. Suárez-Álvarez, A. López-Vázquez, M. Zapico Gonzalez, J. L. Fdez-Morera, B. Díaz-Molina, M. A. Blanco-Gelaz, D. Pascual, J. Martínez-Borra, M. Muro, M. R. Álvarez-López and C. López-Larrea

      Version of Record online: 19 MAY 2007 | DOI: 10.1111/j.1600-6143.2007.01838.x

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      In acute heart transplant rejection, anti-MICA was detectable in a significant number of subjects after heart transplantation and was more frequent among those with severe rejection.

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      Liver Transplant Using Donors After Unexpected Cardiac Death: Novel Preservation Protocol and Acceptance Criteria (pages 1849–1855)

      C. Fondevila, A. J. Hessheimer, A. Ruiz, D. Calatayud, J. Ferrer, R. Charco, J. Fuster, M. Navasa, A. Rimola, P. Taurá, P. Ginés, M. Manyalich and J. C. García-Valdecasas

      Version of Record online: 9 JUN 2007 | DOI: 10.1111/j.1600-6143.2007.01846.x

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      Liver grafts arising from donors after unexpected cardiac death can be successfully transplanted if they demonstrate a favorable evolution during normothermic extracorporeal membrane oxygenation prior to recovery.

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      Lung Transplant Metalloproteinase Levels Are Elevated Prior to Bronchiolitis Obliterans Syndrome (pages 1856–1861)

      G. N. Smith Jr, E. A. Mickler, K. K. Payne, J. Lee, M. Duncan, J. Reynolds, B. Foresman and D. S. Wilkes

      Version of Record online: 25 MAY 2007 | DOI: 10.1111/j.1600-6143.2007.01850.x

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      Elevated expression of MMP8, MMP9, and TIMP1 occurred early and was sustained for the period of this study, and is probably associated with lung transplantation itself rather than infection or rejection.

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      Genitourinary Tuberculosis After Renal Transplantation—A Report of Three Cases with a Good Clinical Outcome (pages 1862–1864)

      S. Nayak and R. Satish

      Version of Record online: 25 MAY 2007 | DOI: 10.1111/j.1600-6143.2007.01853.x

      Genitourinary tuberculosis post-renal transplant has a variable presentation with good response to therapy.

  8. Case Reports

    1. Top of page
    2. Special Feature
    3. Personal Viewpoints
    4. Ethics Corner
    5. Meeting Report
    6. Original Articles Basic Science
    7. Original Articles Clinical Science
    8. Brief Communications
    9. Case Reports
    10. Book Review
    11. Erratum
    1. You have free access to this content
      Sticky Platelet Syndrome: An Underrecognized Cause of Graft Dysfunction and Thromboembolic Complications in Renal Transplant Recipients (pages 1865–1868)

      A. S. Mühlfeld, M. Ketteler, K. Schwamborn, F. Eitner, B. Schneider, U. Gladziwa, R. Knüchel and J. Floege

      Version of Record online: 26 MAY 2007 | DOI: 10.1111/j.1600-6143.2007.01835.x

      The recently described sticky platelet syndrome, which is associated with vascular occlusion, was associated with complicated courses in three renal transplant recipients, suggesting that patients with a history of thrombosis should be screened for this entity and treated with aspirin.

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      Retroversus Implantation of a Liver Graft: A Novel Approach to the Deceased Donor with Situs Inversus Totalis (pages 1869–1871)

      J. J. Pomposelli, M. A. DaCosta, K. McPartland and R. L. Jenkins

      Version of Record online: 19 MAY 2007 | DOI: 10.1111/j.1600-6143.2007.01843.x

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      This novel approach to implantation of a liver graft from a donor with situs inversus involves 180° ventral-caudal (backwards) rotation of the liver graft along the axis of the vena cava.

  9. Book Review

    1. Top of page
    2. Special Feature
    3. Personal Viewpoints
    4. Ethics Corner
    5. Meeting Report
    6. Original Articles Basic Science
    7. Original Articles Clinical Science
    8. Brief Communications
    9. Case Reports
    10. Book Review
    11. Erratum
    1. You have free access to this content
      Book Review (page 1872)

      Richard Freeman

      Version of Record online: 9 JUN 2007 | DOI: 10.1111/j.1600-6143.2007.01854.x

  10. Erratum

    1. Top of page
    2. Special Feature
    3. Personal Viewpoints
    4. Ethics Corner
    5. Meeting Report
    6. Original Articles Basic Science
    7. Original Articles Clinical Science
    8. Brief Communications
    9. Case Reports
    10. Book Review
    11. Erratum
    1. You have free access to this content
      Erratum (page 1873)

      Version of Record online: 26 MAY 2007 | DOI: 10.1111/j.1600-6143.2007.01862.x

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