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American Journal of Transplantation

Cover image for Vol. 7 Issue 9

September 2007

Volume 7, Issue 9

Pages 2059–2216

  1. Special Editorial

    1. Top of page
    2. Special Editorial
    3. Special Feature
    4. Editorial
    5. Minireviews
    6. Original Articles Basic Science
    7. Original Articles Clinical Science
    8. Brief Communications
    9. Case Reports
    10. Letter to the Editor
    11. Erratum
    1. You have free access to this content
      The Perils of Organ Retrieval (page 2059)

      G. B. Klintmalm

      Version of Record online: 9 AUG 2007 | DOI: 10.1111/j.1600-6143.2007.01916.x

      The tragedy in Michigan reminds us to remember the people who put their lives on the line to help others to live, and the high price that they and their families sometimes have to pay. See also tribute by Merion in this issue on page 2060.

  2. Special Feature

    1. Top of page
    2. Special Editorial
    3. Special Feature
    4. Editorial
    5. Minireviews
    6. Original Articles Basic Science
    7. Original Articles Clinical Science
    8. Brief Communications
    9. Case Reports
    10. Letter to the Editor
    11. Erratum
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      In Memoriam – University of Michigan Transplant Flight Team, June 4, 2007 (pages 2060–2061)

      Robert M. Merion

      Version of Record online: 9 AUG 2007 | DOI: 10.1111/j.1600-6143.2007.01915.x

      AJT and the transplant community are mourning the loss of four brave professionals who died in a tragic airplane crash while retrieving organs. See also editorial by Klintmalm in this issue on page 2059.

  3. Editorial

    1. Top of page
    2. Special Editorial
    3. Special Feature
    4. Editorial
    5. Minireviews
    6. Original Articles Basic Science
    7. Original Articles Clinical Science
    8. Brief Communications
    9. Case Reports
    10. Letter to the Editor
    11. Erratum
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      Valganciclovir Versus IV Ganciclovir for Therapy of Cytomegalovirus Viremia: Has Victory Been Achieved? (pages 2062–2063)

      R. K Avery

      Version of Record online: 7 AUG 2007 | DOI: 10.1111/j.1600-6143.2007.01925.x

      The VICTOR trial is an important step in showing that oral valganciclovir is effective in the treatment of CMV disease, but many questions remain before we can declare victory over CMV disease. See also article by Åsberg et al in this issue on page 2106.

  4. Minireviews

    1. Top of page
    2. Special Editorial
    3. Special Feature
    4. Editorial
    5. Minireviews
    6. Original Articles Basic Science
    7. Original Articles Clinical Science
    8. Brief Communications
    9. Case Reports
    10. Letter to the Editor
    11. Erratum
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      Acute Antibody-Mediated Rejection Following Heart Transplantation (pages 2064–2074)

      W. E. Uber, S. E. Self, A. B. Van Bakel and N. L. Pereira

      Version of Record online: 5 JUL 2007 | DOI: 10.1111/j.1600-6143.2007.01900.x

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      AMR is increasingly recognized as an important cause of morbidity and mortality in heart transplantation but treatment strategies must now be developed.

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      Heart Retransplantation (pages 2075–2081)

      M. R. Johnson, K. D. Aaronson, C. E. Canter, J. K. Kirklin, D. M. Mancini, M. R. Mehra, B. Radovancevic, D. O. Taylor and S. A. Webber

      Version of Record online: 9 AUG 2007 | DOI: 10.1111/j.1600-6143.2007.01902.x

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      The working group on heart retransplantation convened as part of a consensus conference on retransplantation sponsored by the AST, ASTS, and NIAID, reviews data concerning heart retransplantation and provides recommendations regarding candidate selection for retransplantation.

  5. Original Articles Basic Science

    1. Top of page
    2. Special Editorial
    3. Special Feature
    4. Editorial
    5. Minireviews
    6. Original Articles Basic Science
    7. Original Articles Clinical Science
    8. Brief Communications
    9. Case Reports
    10. Letter to the Editor
    11. Erratum
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      Corneal Graft Rejection Is Accompanied by Apoptosis of the Endothelium and Is Prevented by Gene Therapy With Bcl-xL (pages 2082–2089)

      R. N Barcia, M. R. Dana and A. Kazlauskas

      Version of Record online: 5 JUL 2007 | DOI: 10.1111/j.1600-6143.2007.01897.x

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      This approach to improving corneal allograft survival involves lentiviral delivery of Bcl-xl to the corneal endothelium.

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      Global Unresponsiveness as a Mechanism of Natural Killer Cell Tolerance in Mixed Xenogeneic Chimeras (pages 2090–2097)

      T. Kawahara, J.-I. Rodriguez-Barbosa, Y. Zhao, G. Zhao and M. Sykes

      Version of Record online: 9 AUG 2007 | DOI: 10.1111/j.1600-6143.2007.01905.x

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      This paper shows that low levels of mixed xenogeneic chimerism induce global unresponsiveness of recipient natural killer cells, supporting an anergy model for NK cell “tolerance”.

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      ESDN Is a Marker of Vascular Remodeling and Regulator of Cell Proliferation in Graft Arteriosclerosis (pages 2098–2105)

      M. M. Sadeghi, L. Esmailzadeh, J. Zhang, X. Guo, A. Asadi, S. Krassilnikova, H. R. Fassaei, G. Luo, R. S. M. Al-Lamki, T. Takahashi, G. Tellides, J. R. Bender and E. R. Rodriguez

      Version of Record online: 9 AUG 2007 | DOI: 10.1111/j.1600-6143.2007.01919.x

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      A neuropilin like protein, ESDN, is increased in the course of vascular remodeling in graft arteriosclerosis and regulates cell proliferation in vascular smooth muscle cells.

  6. Original Articles Clinical Science

    1. Top of page
    2. Special Editorial
    3. Special Feature
    4. Editorial
    5. Minireviews
    6. Original Articles Basic Science
    7. Original Articles Clinical Science
    8. Brief Communications
    9. Case Reports
    10. Letter to the Editor
    11. Erratum
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      Oral Valganciclovir Is Noninferior to Intravenous Ganciclovir for the Treatment of Cytomegalovirus Disease in Solid Organ Transplant Recipients (pages 2106–2113)

      A. Åsberg, A. Humar, H. Rollag, A. G. Jardine, H. Mouas, M. D. Pescovitz, D. Sgarabotto, M. Tuncer, I. L. Noronha, A. Hartmann and on behalf of the VICTOR Study Group

      Version of Record online: 9 AUG 2007 | DOI: 10.1111/j.1600-6143.2007.01910.x

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      Oral valganciclovir is an effective and safe treatment option for CMV disease in solid organ transplant recipients. See also editorial by Avery in this issue on page 2062.

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      Tacrolimus Exposure and Evolution of Renal Allograft Histology in the First Year After Transplantation (pages 2114–2123)

      M. Naesens, E. Lerut, B. V. Damme, Y. Vanrenterghem and D. R. J. Kuypers

      Version of Record online: 3 JUL 2007 | DOI: 10.1111/j.1600-6143.2007.01892.x

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      This study of protocol biopsies shows that immune-mediated injuries remain important in the early progression of chronic allograft pathology while incident tacrolimus exposure is not associated with histological lesions suggestive of CNI-nephrotoxicity.

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      Transplant Glomerulopathy: Subclinical Incidence and Association with Alloantibody (pages 2124–2132)

      J. M. Gloor, S. Sethi, M. D. Stegall, W. D. Park, S. B. Moore, S. DeGoey, M. D. Griffin, T. S. Larson and F. G. Cosio

      Version of Record online: 3 JUL 2007 | DOI: 10.1111/j.1600-6143.2007.01895.x

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      Transplant glomerulopathy is often detected on biopsies showing minimal histologic abnormalities otherwise, and is highly associated with anti-HLA class II antibodies present at transplant indicating that antibody-mediated injury is an important cause of transplant glomerulopathy.

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      The Long-Term Prognosis of Renal Transplant in Patients With Systemic Vasculitis (pages 2133–2139)

      G. Moroni, A. Torri, B. Gallelli, S. Quaglini, C. Pozzi, G. Banfi, F. Poli, G. Montagnino, C. Ponticelli and P. Messa

      Version of Record online: 9 AUG 2007 | DOI: 10.1111/j.1600-6143.2007.01904.x

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      In 19 renal transplant recipients with systemic vasculitis, graft and patient survival was good, despite seven patients having recurrent vasculitis.

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      Identifying High Risk Groups and Quantifying Absolute Risk of Cancer After Kidney Transplantation: A Cohort Study of 15 183 Recipients (pages 2140–2151)

      A. C. Webster, J. C. Craig, J. M. Simpson, M. P. Jones and J. R. Chapman

      Version of Record online: 9 AUG 2007 | DOI: 10.1111/j.1600-6143.2007.01908.x

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      In the Australian and New Zealand Dialysis and Transplant Registry (ANZDATA), cancer rates in kidney recipients are similar to non-transplanted people 20-30 years older but absolute risk differs among patient groups.

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      Increased Urologic Complications in Children After Kidney Transplants for Obstructive and Reflux Uropathy (pages 2152–2157)

      S. Khositseth, V. Askiti, T. E. Nevins, A. J. Matas, E. G. Ingulli, J. S. Najarian, K. J. Gillingham and B. M. Chavers

      Version of Record online: 9 AUG 2007 | DOI: 10.1111/j.1600-6143.2007.01912.x

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      Pediatric patients who underwent a kidney transplant for obstructive or reflux nephropathy developed more urologic complications post-transplant, including acidosis and infections in those undergoing bladder augmentation.

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      Determinants of Coronary Artery Calcification Progression in Renal Transplant Recipients (pages 2158–2164)

      K. Schankel, J. Robinson, R. D. Bloom, C. Guerra, D. Rader, M. Joffe and S. E. Rosas

      Version of Record online: 9 AUG 2007 | DOI: 10.1111/j.1600-6143.2007.01903.x

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      Progression of coronary artery calcification in kidney transplant recipients is associated with white race, hypertension, high body mass index, and lower renal function.

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      Late Graft Loss or Death in Pediatric Liver Transplantation: An Analysis of the SPLIT Database (pages 2165–2171)

      K. A. Soltys, G. V. Mazariegos, R. H. Squires, R. K. Sindhi, R. Anand and The SPLIT Research Group

      Version of Record online: 3 JUL 2007 | DOI: 10.1111/j.1600-6143.2007.01893.x

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      About half of late graft loss after pediatric liver transplantation is related to rejection and late consequence of hepatic arterial thrombosis, whereas mortality is most often due to sepsis, multi-system organ failure, and posttransplant lymphoproliferative disease.

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      Evolution of the NS3 and NS5B Regions of the Hepatitis C Virus During Disease Recurrence After Liver Transplantation (pages 2172–2179)

      A. Massaguer, S. Ramírez, J. A. Carrión, P. González, J. M. Sánchez-Tapias and X. Forns

      Version of Record online: 3 JUL 2007 | DOI: 10.1111/j.1600-6143.2007.01894.x

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      The genetic evolution of the NS3 and NS5B regions of the Hepatitis C virus is diverse after liver transplantation suggesting a complex interplay between viral evolution and clinical outcomes.

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      Ischemic Pre-conditioning in Deceased Donor Liver Transplantation: A Prospective Randomized Clinical Trial (pages 2180–2189)

      A. Amador, L. Grande, J. Martí, R. Deulofeu, R. Miquel, A. Solá, G. Rodriguez-Laiz, J. Ferrer, C. Fondevila, R. Charco, J. Fuster, G. Hotter and J. C. García-Valdecasas

      Version of Record online: 9 AUG 2007 | DOI: 10.1111/j.1600-6143.2007.01914.x

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      Ischemic preconditioning in this trial was associated with liver aminotransferase elevation and re-operation, but not with significantly less primary non-function.

  7. Brief Communications

    1. Top of page
    2. Special Editorial
    3. Special Feature
    4. Editorial
    5. Minireviews
    6. Original Articles Basic Science
    7. Original Articles Clinical Science
    8. Brief Communications
    9. Case Reports
    10. Letter to the Editor
    11. Erratum
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      Evidence of Immune Tolerance to Blood Group Antigens in a Case of ABO-Incompatible Pediatric Liver Transplantation (pages 2190–2194)

      H. Ohdan, W. Zhou, Y. Tanaka, T. Irei, Y. Fuchimoto, H. Egawa and T. Asahara

      Version of Record online: 9 AUG 2007 | DOI: 10.1111/j.1600-6143.2007.01901.x

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      This human PBMC-NOD/SCID chimera model demonstrated immune tolerance to blood group-A antigens in a blood group-O pediatric recipient of a group-A liver allograft.

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      Major Coagulation Disturbances During Fractionated Plasma Separation and Adsorption (pages 2195–2199)

      B. K. I. Meijers, P. Verhamme, F. Nevens, M. F. Hoylaerts, B. Bammens, A. Wilmer, J. Arnout, Y. Vanrenterghem and P. Evenepoel

      Version of Record online: 9 AUG 2007 | DOI: 10.1111/j.1600-6143.2007.01909.x

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      Fractionated plasma separation and adsorption results in loss of coagulation factors and is associated with repeated thrombosis in hemodialysis patients.

  8. Case Reports

    1. Top of page
    2. Special Editorial
    3. Special Feature
    4. Editorial
    5. Minireviews
    6. Original Articles Basic Science
    7. Original Articles Clinical Science
    8. Brief Communications
    9. Case Reports
    10. Letter to the Editor
    11. Erratum
    1. You have free access to this content
      Auxiliary Liver Transplantation for Propionic Acidemia: A 10-Year Follow-Up (pages 2200–2203)

      M. Rela, N. Battula, M. Madanur, G. Mieli-Vergani, A. Dhawan, M. Champion, J. Raiman and N. Heaton

      Version of Record online: 9 AUG 2007 | DOI: 10.1111/j.1600-6143.2007.01899.x

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      This child who underwent auxiliary liver transplantation has acceptable outcome parameters after 10 years.

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      Discontinuation of Living Donor Liver Transplantation for PSC Due to Histological Abnormalities in Intraoperative Donor Liver Biopsy (pages 2204–2207)

      Y. Hasegawa, S. Kawachi, M. Shimazu, K. Hoshino, M. Tanabe, Y. Fuchimoto, H. Obara, M. Shinoda, H. Shimizu, Y. Yamada, T. Akatsu, R. Irie, M. Sakamoto, Y. Morikawa and M. Kitajima

      Version of Record online: 5 JUL 2007 | DOI: 10.1111/j.1600-6143.2007.01898.x

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      Living donor liver transplantation for PSC was discontinued, because the histological findings in intraoperative donor liver biopsy were identical to those of early-stage PSC.

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      Veno-Occlusive Disease of the Liver After Lung Transplantation (pages 2208–2211)

      F. S. De Fontbrune, H. Mal, G. Dauriat, O. Brugière, G. Biondi, C. Taillé, D. Valla, Y. Castier and M. Fournier

      Version of Record online: 9 AUG 2007 | DOI: 10.1111/j.1600-6143.2007.01913.x

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      This recipient of a bilateral lung transplant developed veno-occlusive disease of the liver, possibly related to azathioprine.

  9. Letter to the Editor

    1. Top of page
    2. Special Editorial
    3. Special Feature
    4. Editorial
    5. Minireviews
    6. Original Articles Basic Science
    7. Original Articles Clinical Science
    8. Brief Communications
    9. Case Reports
    10. Letter to the Editor
    11. Erratum
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  10. Erratum

    1. Top of page
    2. Special Editorial
    3. Special Feature
    4. Editorial
    5. Minireviews
    6. Original Articles Basic Science
    7. Original Articles Clinical Science
    8. Brief Communications
    9. Case Reports
    10. Letter to the Editor
    11. Erratum
    1. You have free access to this content
      Erratum (page 2214)

      Version of Record online: 9 AUG 2007 | DOI: 10.1111/j.1600-6143.2007.01906.x

      This article corrects:

      Kidney and Pancreas Transplantation in the United States, 1996–2005

      Vol. 7, Issue Supplement s1, 1359–1375, Version of Record online: 11 APR 2007

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      Erratum (page 2215)

      Version of Record online: 9 AUG 2007 | DOI: 10.1111/j.1600-6143.2007.01907.x

      This article corrects:
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      Erratum (page 2216)

      Version of Record online: 3 JUL 2007 | DOI: 10.1111/j.1600-6143.2007.01896.x

      This article corrects:

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