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American Journal of Transplantation

Cover image for Vol. 8 Issue 11

November 2008

Volume 8, Issue 11

Pages 2177–2479

  1. The AJT Report

    1. Top of page
    2. The AJT Report
    3. Editorials
    4. Minireview Series on Post-transplant Malignancies
    5. Minireview
    6. Personal Viewpoint
    7. Meeting Reports
    8. Original Articles:
    9. Brief Communication: Basic Science
    10. Original Articles:
    11. Brief Communication: Clinical Science
    12. Case Reports
    13. Letter to the Editor
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  2. Editorials

    1. Top of page
    2. The AJT Report
    3. Editorials
    4. Minireview Series on Post-transplant Malignancies
    5. Minireview
    6. Personal Viewpoint
    7. Meeting Reports
    8. Original Articles:
    9. Brief Communication: Basic Science
    10. Original Articles:
    11. Brief Communication: Clinical Science
    12. Case Reports
    13. Letter to the Editor
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      The Promise and Pitfalls of Transplant Centers (pages 2179–2180)

      D. A. Axelrod, K. Lentine, P. Salvalaggio and M. Schnitzler

      Article first published online: 9 OCT 2008 | DOI: 10.1111/j.1600-6143.2008.02438.x

      There are advantages of integrated transplant centers, within the nation's academic medical centers, but there are also potential difficulties in navigating the fiscal and administrative relationships. See also article by Howard and Kaplan in this issue on page 2225.

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      An Appeal for Zero-Time Biopsies in Renal Transplantation (pages 2181–2182)

      M. Mengel and B. Sis

      Article first published online: 8 SEP 2008 | DOI: 10.1111/j.1600-6143.2008.02380.x

      New laboratory criteria for predicting organ performance at the time of transplantation are needed, but any proposed test requires robust multi-centric validation before it can become widely accepted as standard of care. See also articles by Anglicheau and Philosophe in this issue on pages 2316 and 2325.

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      Posttransplantation Treatment of Recurrent hepatitis C: Is the Juice Worth the Squeeze? (pages 2183–2184)

      B. E. Fortune and J. F. Trotter

      Article first published online: 9 OCT 2008 | DOI: 10.1111/j.1600-6143.2008.02439.x

      Treatment of recurrent hepatitis C may prolong graft survival in carefully selected patients. See also article by Veldt et al in this issue on page 2426.

  3. Minireview Series on Post-transplant Malignancies

    1. Top of page
    2. The AJT Report
    3. Editorials
    4. Minireview Series on Post-transplant Malignancies
    5. Minireview
    6. Personal Viewpoint
    7. Meeting Reports
    8. Original Articles:
    9. Brief Communication: Basic Science
    10. Original Articles:
    11. Brief Communication: Clinical Science
    12. Case Reports
    13. Letter to the Editor
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      Managing Cancer Risk and Decision Making After Kidney Transplantation (pages 2185–2191)

      A. C. Webster, G. Wong, J. C. Craig and J. R. Chapman

      Article first published online: 8 SEP 2008 | DOI: 10.1111/j.1600-6143.2008.02385.x

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      This minireview critically explores the assumptions underpinning primary prevention, immunization, chemoprevention and screening programs as they apply to cancer in the post-transplant population.

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      Skin Cancer in Organ Transplant Recipients—Where Do We Stand Today? (pages 2192–2198)

      C. Ulrich, J. Kanitakis, E. Stockfleth and S. Euvrard

      Article first published online: 8 SEP 2008 | DOI: 10.1111/j.1600-6143.2008.02386.x

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      Improvements in prevention and management of post-transplant skin cancers requires an interdisciplinary approach, including revision of immunosuppression, new dermatological treatments, and education about photoprotection.

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      Molecular Concepts of Virus Infections Causing Skin Cancer in Organ Transplant Recipients (pages 2199–2204)

      I. Nindl and F. Rösl

      Article first published online: 10 SEP 2008 | DOI: 10.1111/j.1600-6143.2008.02392.x

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      Tumor viruses can act as direct carcinogens such as HHV-8 in Kaposi's sarcoma, or indirect carcinogens such as HPV, which potentiates carcinogens such as UV light.

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      Molecular and Immunologic Mechanisms of Cancer Pathogenesis in Solid Organ Transplant Recipients (pages 2205–2211)

      O. M. Martinez and F. R. De Gruijl

      Article first published online: 17 SEP 2008 | DOI: 10.1111/j.1600-6143.2008.02368.x

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      The basic genetic, viral and host mechanisms that contribute to the pathogenesis of post-transplant skin cancer and Epstein Barr virus B cell lymphomas, as well as the impact of immunosuppression on these processes, are discussed.

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      mTOR, Cancer and Transplantation (pages 2212–2218)

      Edward K. Geissler, Hans J. Schlitt and George Thomas

      Article first published online: 10 SEP 2008 | DOI: 10.1111/j.1600-6143.2008.02391.x

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      The mTOR pathway presents opportunities and challenges in relationship to immunosuppression and prevention and management of malignancy in transplant recipients.

  4. Minireview

    1. Top of page
    2. The AJT Report
    3. Editorials
    4. Minireview Series on Post-transplant Malignancies
    5. Minireview
    6. Personal Viewpoint
    7. Meeting Reports
    8. Original Articles:
    9. Brief Communication: Basic Science
    10. Original Articles:
    11. Brief Communication: Clinical Science
    12. Case Reports
    13. Letter to the Editor
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      Severe Left Ventricular Systolic Dysfunction May Reverse with Renal Transplantation: Uremic Cardiomyopathy and Cardiorenal Syndrome (pages 2219–2224)

      R. Zolty, P. J. Hynes and T. J. Vittorio

      Article first published online: 19 SEP 2008 | DOI: 10.1111/j.1600-6143.2008.02407.x

      Chronic kidney disease and the concomitant uremic milieu are often associated with severe left ventricular systolic dysfunction, which might be reversible with kidney transplantation despite previous beliefs of a high surgical risk.

  5. Personal Viewpoint

    1. Top of page
    2. The AJT Report
    3. Editorials
    4. Minireview Series on Post-transplant Malignancies
    5. Minireview
    6. Personal Viewpoint
    7. Meeting Reports
    8. Original Articles:
    9. Brief Communication: Basic Science
    10. Original Articles:
    11. Brief Communication: Clinical Science
    12. Case Reports
    13. Letter to the Editor
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      The Time Is Now: Formation of True Transplant Centers (pages 2225–2229)

      R. J. Howard and Bruce Kaplan

      Article first published online: 10 SEP 2008 | DOI: 10.1111/j.1600-6143.2008.02388.x

      Modern complex medical care such as organ transplantation can be delivered better by multidisciplinary transplant centers outside the traditional departmental structure. See also editorial by Axelrod and Schnitzler in this issue on page 2179.

  6. Meeting Reports

    1. Top of page
    2. The AJT Report
    3. Editorials
    4. Minireview Series on Post-transplant Malignancies
    5. Minireview
    6. Personal Viewpoint
    7. Meeting Reports
    8. Original Articles:
    9. Brief Communication: Basic Science
    10. Original Articles:
    11. Brief Communication: Clinical Science
    12. Case Reports
    13. Letter to the Editor
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      Adolescent Transition to Adult Care in Solid Organ Transplantation: A consensus conference report (pages 2230–2242)

      L. E. Bell, S. M. Bartosh, C. L. Davis, F. Dobbels, A. Al-Uzri, D. Lotstein, J. Reiss, V. R. Dharnidharka and on behalf of the conference attendees

      Article first published online: 24 SEP 2008 | DOI: 10.1111/j.1600-6143.2008.02415.x

      Children with solid organ transplants are reaching adulthood in ever increasing numbers, and health professionals need to effectively facilitate their transition from adolescent to adult care. This consensus conference report explores the challenges and summarizes recommendations for navigating this potentially precarious passage.

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      Proceedings of Consensus Conference on Simultaneous Liver Kidney Transplantation (SLK) (pages 2243–2251)

      J. D. Eason, T. A. Gonwa, C. L. Davis, R. S. Sung, D. Gerber and R. D. Bloom

      Article first published online: 19 SEP 2008 | DOI: 10.1111/j.1600-6143.2008.02416.x

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      This report highlights the most recent data on simultaneous liver- kidney transplantation and consensus on indications and recommendations for standardized listing criteria for patients with severe renal and liver disease being considered for combined transplants.

  7. Original Articles:

    1. Top of page
    2. The AJT Report
    3. Editorials
    4. Minireview Series on Post-transplant Malignancies
    5. Minireview
    6. Personal Viewpoint
    7. Meeting Reports
    8. Original Articles:
    9. Brief Communication: Basic Science
    10. Original Articles:
    11. Brief Communication: Clinical Science
    12. Case Reports
    13. Letter to the Editor
    1. Basic Science

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      Expanded Nonhuman Primate Tregs Exhibit a Unique Gene Expression Signature and Potently Downregulate Alloimmune Responses (pages 2252–2264)

      A. Anderson, C. L. Martens, R. Hendrix, L. L. Stempora, W. P. Miller, K. Hamby, M. Russell, E. Strobert, B. R. Blazar, T. C. Pearson, C. P. Larsen and L. S. Kean

      Article first published online: 17 SEP 2008 | DOI: 10.1111/j.1600-6143.2008.02376.x

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      Regulatory T cells purified and expanded from Rhesus macaques in quantities sufficient for use as an in vivo therapeutic were analyzed by gene arrays, revealing a unique gene expression signature, and by CFSE-MLR, which demonstrated their capacity to down-regulate allo-stimulated T cell proliferation.

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      Fc-Disabled Anti-Mouse CD40L Antibodies Retain Efficacy in Promoting Transplantation Tolerance (pages 2265–2271)

      S. R. Daley, S. P. Cobbold and H. Waldmann

      Article first published online: 8 SEP 2008 | DOI: 10.1111/j.1600-6143.2008.02382.x

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      CD40L antibodies engineered to minimize binding to Fc receptors and complement retain activity in tolerance-inducing protocols, so enabling safer use of such drugs in the clinic.

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      An Antibody Combination That Targets Activated T Cells Extends Graft Survival in Sensitized Recipients (pages 2272–2282)

      R. E. Greenlaw, N. J. Gardner, C. A. Farrar, H. Shariff, S. H. Sacks, H. Yagita, E. Simpson and S. Jurcevic

      Article first published online: 10 SEP 2008 | DOI: 10.1111/j.1600-6143.2008.02393.x

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      A combination of CD154-, CD70- and CD8-specific antibodies plus short-term rapamycin therapy acts synergistically to remove activated T cells and achieves impressive graft survival in a stringent, pre-sensitized skin transplant model.

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      Cyclosporine-Induced Endoplasmic Reticulum Stress Triggers Tubular Phenotypic Changes and Death (pages 2283–2296)

      N. Pallet, N. Bouvier, A. Bendjallabah, M. Rabant, J. P. Flinois, A. Hertig, C. Legendre, P. Beaune, E. Thervet and D. Anglicheau

      Article first published online: 10 SEP 2008 | DOI: 10.1111/j.1600-6143.2008.02396.x

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      Endoplasmic reticulum stress may contribute to cyclosporine nephrotoxicity and that its inhibition with salubrinal is nephroprotective.

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      An Immunomodulatory Role for Follistatin-Like 1 in Heart Allograft Transplantation (pages 2297–2306)

      J. B. Le Luduec, T. Condamine, C. Louvet, P. Thebault, J.-M. Heslan, M. Heslan, E. Chiffoleau and M.-C. Cuturi

      Article first published online: 25 SEP 2008 | DOI: 10.1111/j.1600-6143.2008.02398.x

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      Follistatin-like 1 (FSTL1) is overexpressed in tolerated rat heart allografts and when overexpressed by gene transfer prolongs allograft survival, probably by inhibiting inflammatory response.

  8. Brief Communication: Basic Science

    1. Top of page
    2. The AJT Report
    3. Editorials
    4. Minireview Series on Post-transplant Malignancies
    5. Minireview
    6. Personal Viewpoint
    7. Meeting Reports
    8. Original Articles:
    9. Brief Communication: Basic Science
    10. Original Articles:
    11. Brief Communication: Clinical Science
    12. Case Reports
    13. Letter to the Editor
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      Tolerance Induction or Sensitization in Mice Exposed to Noninherited Maternal Antigens (NIMA) (pages 2307–2315)

      M. L. Molitor-Dart, J. Andrassy, L. D. Haynes and W. J. Burlingham

      Article first published online: 9 OCT 2008 | DOI: 10.1111/j.1600-6143.2008.02417.x

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      Exposure to non-inherited maternal antigens in the homozygous offspring of H-2 heterozygous mothers can result in opposite outcomes-tolerization or sensitization -to heart allografts in the adult mouse, depending on the mouse strain combination tested.

  9. Original Articles:

    1. Top of page
    2. The AJT Report
    3. Editorials
    4. Minireview Series on Post-transplant Malignancies
    5. Minireview
    6. Personal Viewpoint
    7. Meeting Reports
    8. Original Articles:
    9. Brief Communication: Basic Science
    10. Original Articles:
    11. Brief Communication: Clinical Science
    12. Case Reports
    13. Letter to the Editor
    1. Clinical Science

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      The Maryland Aggregate Pathology Index: A Deceased Donor Kidney Biopsy Scoring System for Predicting Graft Failure (pages 2316–2324)

      R. B. Munivenkatappa, E. J. Schweitzer, J. C. Papadimitriou, C. B. Drachenberg, K. A. Thom, E. N. Perencevich, A. Haririan, F. Rasetto, M. Cooper, L. Campos, R. N. Barth, S. T. Bartlett and B. Philosophe

      Article first published online: 17 SEP 2008 | DOI: 10.1111/j.1600-6143.2008.02370.x

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      A composite histopathology score developed on pre-transplant biopsies of deceased donor kidneys, based on glomerulosclerosis, fibrosis, arterial wall thickening, and other features correlated strongly with graft survival at five years. See editorial by Mengel in this issue on page 2181.

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      A Simple Clinico-Histopathological Composite Scoring System Is Highly Predictive of Graft Outcomes in Marginal Donors (pages 2325–2334)

      D. Anglicheau, A. Loupy, C. Lefaucheur, F. Pessione, I. Létourneau, I. Côté, K. Gaha, L.-H. Noël, N. Patey, D. Droz, F. Martinez, J. Zuber, D. Glotz, E. Thervet and C. Legendre

      Article first published online: 10 SEP 2008 | DOI: 10.1111/j.1600-6143.2008.02394.x

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      In pre-transplant biopsies obtained from 313 marginal donors (≥50 years old), clinical scores were weak predictors of graft outcomes, but a clinico-pathological composite score including donor serum creatinine, donor hypertension and global glomerulosclerosis was able to predict low eGFR (<25 mL/min/1.73 m2) at 1 year. See editorial by Mengel in this issue on page 2181.

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      Anti-HLA Donor-Specific Antibodies Detected in Positive B-Cell Crossmatches by Luminex® Predict Late Graft Loss (pages 2335–2342)

      H. S. Eng, G. Bennett, E. Tsiopelas, M. Lake, I. Humphreys, S. H. Chang, P. T. H. Coates and G. R. Russ

      Article first published online: 8 SEP 2008 | DOI: 10.1111/j.1600-6143.2008.02387.x

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      This single center study showed that Luminex defined anti-HLA donor specific antibodies were present in only one third of positive B-cell crossmatches, but when present predicted higher rejection rates and poorer 5 year kidney graft survival.

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      Monozygotic Transplantation: Concerns and Opportunities (pages 2343–2351)

      N. Krishnan, P. M. Buchanan, N. Dzebisashvili, H. Xiao, M. A. Schnitzler and D. C. Brennan

      Article first published online: 19 SEP 2008 | DOI: 10.1111/j.1600-6143.2008.02378.x

      The authors report the first known renal transplant between a monozygotic pair of a triplet birth, and the immunosuppression and outcomes of monozygotic twin transplants as recorded in the OPTN database, showing that minimal to no immunosuppression is possible with monozygotic transplantation.

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      Survival of Patients on the Kidney Transplant Wait List: Relationship to Cardiac Troponin T (pages 2352–2359)

      L. J. Hickson, F. G. Cosio, Z. M. El-Zoghby, J. M. Gloor, W. K. Kremers, M. D. Stegall, M. D. Griffin and A. S. Jaffe

      Article first published online: 10 SEP 2008 | DOI: 10.1111/j.1600-6143.2008.02395.x

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      Normal troponin T levels relate with excellent kidney transplant survival even in high risk patients, whereas elevated levels correlate with increased mortality independent of other risk factors.

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      Impact of Immunosuppressive Treatment on Endothelial Biomarkers After Kidney Transplantation (pages 2360–2367)

      G. Al-Massarani, H. Vacher-Coponat, P. Paul, A. Widemann, L. Arnaud, A. Loundou, S. Robert, Y. Berland, F. Dignat-George and L. Camoin-Jau

      Article first published online: 25 SEP 2008 | DOI: 10.1111/j.1600-6143.2008.02399.x

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      Combined analysis of endothelial injury markers (circulating endothelial cells, microparticles, and soluble VCAM-1) before and after transplantation confirmed favorable changes after renal transplantation, and showed differences related to the immunosuppressive protocol, cardiovascular disease, and CMV infection.

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      Polyomavirus BK Replication Dynamics In Vivo and In Silico to Predict Cytopathology and Viral Clearance in Kidney Transplants (pages 2368–2377)

      G. A. Funk, R. Gosert, P. Comoli, F. Ginevri and H. H. Hirsch

      Article first published online: 25 SEP 2008 | DOI: 10.1111/j.1600-6143.2008.02402.x

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      Assessment of BK virus loads in urine and plasma provides novel insights into the importance of replication in renal tubular epithelium as opposed to urothelial cells, and of the importance of curtailing replication in kidney cells in terminating viremia.

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      Chronic Kidney Disease After Hematopoietic Cell Transplantation: A Systematic Review (pages 2378–2390)

      M. J. Ellis, C. R. Parikh, J. K. Inrig, M. Kambay and U. D. Patel

      Article first published online: 25 SEP 2008 | DOI: 10.1111/j.1600-6143.2008.02408.x

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      This study of the available literature on chronic kidney disease (CKD) after hematopoietic cell transplantation (HCT) confirmed that the incidence of CKD is high among long-term survivors, highlighting the need for studies to define underlying mechanisms and opportunities for prevention.

      Corrected by:

      Erratum

      Vol. 9, Issue 4, 865, Article first published online: 16 MAR 2009

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      Association of Lower Costs of Pulsatile Machine Perfusion in Renal Transplantation from Expanded Criteria Donors (pages 2391–2401)

      P. M. Buchanan, K. L. Lentine, T. E. Burroughs, M. A. Schnitzler and P. R. Salvalaggio

      Article first published online: 25 SEP 2008 | DOI: 10.1111/j.1600-6143.2008.02412.x

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      Pulsatile machine perfusion utilization is associated with a significantly lower cost of care for the transplant hospitalization in expanded criteria donor renal recipients on Medicare.

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      Neighborhood Poverty and Kidney Transplantation Among US Asians and Pacific Islanders with End-Stage Renal Disease (pages 2402–2409)

      Y. N. Hall, A. M. O'Hare, B. A. Young, E. J. Boyko and G. M. Chertow

      Article first published online: 19 SEP 2008 | DOI: 10.1111/j.1600-6143.2008.02413.x

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      Regardless of the level of neighborhood poverty, US Asians and Pacific Islanders are less likely than US whites to receive a kidney transplant and that this disparity is most pronounced in the poorest neighborhoods.

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      2202 Kidney Transplant Recipients with 10 Years of Graft Function: What Happens Next? (pages 2410–2419)

      A. J. Matas, K. J. Gillingham, A. Humar, R. Kandaswamy, D. E. R. Sutherland, W. D. Payne, T. B. Dunn and J. S. Najarian

      Article first published online: 9 OCT 2008 | DOI: 10.1111/j.1600-6143.2008.02414.x

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      This retrospective study of long-term outcome for kidney transplants recipients with 10 years of graft function found a high rate of morbidity and early mortality.

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      Donor Infection and Transmission to the Recipient of a Solid Allograft (pages 2420–2425)

      O. Len, J. Gavaldà, M. Blanes, M. Montejo, R. San Juan, A. Moreno, J. Carratalà, J. De La Torre-Cisneros, G. Bou, E. Cordero, P. Muñoz, V. Cuervas-Mons, M. T. Alvarez, N. Borrell, J. Fortun, A. Pahissa and on behalf of RESITRA (Spanish Research Network for the Study of Infection in Transplantation), Spain

      Article first published online: 25 SEP 2008 | DOI: 10.1111/j.1600-6143.2008.02397.x

      Although donor non-viral infection is not an infrequent event, the rate of transmission to the recipient is low, with no deleterious impact on 30-day survival.

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      Impact of Pegylated Interferon and Ribavirin Treatment on Graft Survival in Liver Transplant Patients with Recurrent Hepatitis C Infection (pages 2426–2433)

      B. J. Veldt, J. J. Poterucha, K. D. S. Watt, R. H. Wiesner, J. E. Hay, W. K. Kremers, C. B. Rosen, J. K. Heimbach and M. R. Charlton

      Article first published online: 22 AUG 2008 | DOI: 10.1111/j.1600-6143.2008.02362.x

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      This paper examines the superior patient and graft survival experienced by patients with HCV infection who receive antiviral therapy following liver transplantation. See also editorial by Fortune and Trotter in this issue on page 2183

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      The Programmed Death (PD)-1/PD-Ligand 1 Pathway Regulates Graft-Versus-Host-Reactive CD8 T Cells After Liver Transplantation (pages 2434–2444)

      M. Schuchmann, R. G. Meyer, E. Distler, E. Von Stebut, J. Kuball, E. Schnürer, T. Wölfel, M. Theobald, A. Konur, S. Gregor, O. Schreiner, C. Huber, P. R. Galle, G. Otto and W. Herr

      Article first published online: 25 SEP 2008 | DOI: 10.1111/j.1600-6143.2008.02401.x

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      Ex vivo analysis of blood lymphocytes from two liver allograft recipients with severe acute graft-versus-host disease detected high numbers of circulating allo-reactive donor CD8 T cells that were negatively regulated by the programmed death (PD)-1/PD-ligand 1 pathway.

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      Survival in Portopulmonary Hypertension: Mayo Clinic Experience Categorized by Treatment Subgroups (pages 2445–2453)

      K. L. Swanson, R. H. Wiesner, S. L. Nyberg, C. B. Rosen and M. J. Krowka

      Article first published online: 8 SEP 2008 | DOI: 10.1111/j.1600-6143.2008.02384.x

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      Given the dismal natural history of portopulmonary hypertension (1- and 5-year survival 46 and 14%), medical therapy for portopulmonary hypertension should be considered.

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      Late Primary Graft Dysfunction After Lung Transplantation and Bronchiolitis Obliterans Syndrome (pages 2454–2462)

      H. J. Huang, R. D. Yusen, B. F. Meyers, M. J. Walter, T. Mohanakumar, G. A. Patterson, E. P. Trulock and R. R. Hachem

      Article first published online: 10 SEP 2008 | DOI: 10.1111/j.1600-6143.2008.02389.x

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      All grades of PGD at all time points after lung transplantation are significant risk factors for BOS development and progression independent of acute rejection, lymphocytic bronchitis, and respiratory viral infections.

  10. Brief Communication: Clinical Science

    1. Top of page
    2. The AJT Report
    3. Editorials
    4. Minireview Series on Post-transplant Malignancies
    5. Minireview
    6. Personal Viewpoint
    7. Meeting Reports
    8. Original Articles:
    9. Brief Communication: Basic Science
    10. Original Articles:
    11. Brief Communication: Clinical Science
    12. Case Reports
    13. Letter to the Editor
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      Prolonged Insulin Independence After Islet Allotransplants in Recipients with Type 1 Diabetes (pages 2463–2470)

      M. D. Bellin, R. Kandaswamy, J. Parkey, H.-J. Zhang, B. Liu, S. H. Ihm, J. D. Ansite, J. Witson, P. Bansal-Pakala, A. N. Balamurugan, K. Papas, D. E. R. Sutherland, A. Moran and B. J. Hering

      Article first published online: 19 SEP 2008 | DOI: 10.1111/j.1600-6143.2008.02404.x

      In 4 of 6 type 1 diabetic islet allotransplant recipients treated with ATG and etanercept induction therapy and with cyclosporine and, initially, everolimus for maintenance, insulin independence was maintained for a mean of >3 years.

      Corrected by:

      Erratum

      Vol. 10, Issue 5, 1337, Article first published online: 1 FEB 2010

  11. Case Reports

    1. Top of page
    2. The AJT Report
    3. Editorials
    4. Minireview Series on Post-transplant Malignancies
    5. Minireview
    6. Personal Viewpoint
    7. Meeting Reports
    8. Original Articles:
    9. Brief Communication: Basic Science
    10. Original Articles:
    11. Brief Communication: Clinical Science
    12. Case Reports
    13. Letter to the Editor
    1. You have free access to this content
      Chronic Lymphocytic Leukemia: A Hazardous Condition Before Kidney Transplantation (pages 2471–2475)

      G. D'Ythurbide, P. Coppo, A. Adem, P. Callard, J. Dantal, F. Chantrel, M. Godin, L. Braun-Parvez, B. Moulin, P. Moskovtchenko, N. Ouali, E. Rondeau and A. Hertig

      Article first published online: 8 SEP 2008 | DOI: 10.1111/j.1600-6143.2008.02383.x

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      This report, describing the outcome of four ESRD patients transplanted with a deceased donor kidney despite the presence of a chronic lymphocytic leukemia, stresses out that a conventional immunosuppressive regimen is clearly un-adapted in this context.

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      Intentional ABO-Incompatible Lung Transplantation (pages 2476–2478)

      M. Strüber, G. Warnecke, C. Hafer, L. Goudeva, C. Fegbeutel, S. Fischer, J. Gottlieb, M. Avsar, A. R. Simon and A. Haverich

      Article first published online: 19 SEP 2008 | DOI: 10.1111/j.1600-6143.2008.02405.x

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      In this first case of intentional ABO incompatible lung transplantation, a blood group AB donor organ was implanted into a critically ill blood group O recipient in order to avoid excessive waiting time, followed by a favorable clinical course.

  12. Letter to the Editor

    1. Top of page
    2. The AJT Report
    3. Editorials
    4. Minireview Series on Post-transplant Malignancies
    5. Minireview
    6. Personal Viewpoint
    7. Meeting Reports
    8. Original Articles:
    9. Brief Communication: Basic Science
    10. Original Articles:
    11. Brief Communication: Clinical Science
    12. Case Reports
    13. Letter to the Editor
    1. You have free access to this content

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