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American Journal of Transplantation

Cover image for Vol. 13 Issue 3

March 2013

Volume 13, Issue 3

Pages 531–825

  1. The AJT Report

    1. Top of page
    2. The AJT Report
    3. Literature Watch
    4. Editorials
    5. Minireviews
    6. Meeting Report
    7. Original Articles
    8. Brief Communications
    9. Case Reports
    10. Reports From the CDC: MMWR
    11. Book Review
    12. Images in Transplantation
    13. Letter to the Editor
    1. You have free access to this content
      The AJT Report: News and issues that affect organ and tissue transplantation (pages 531–532)

      Sue Pondrom

      Article first published online: 25 FEB 2013 | DOI: 10.1111/ajt.12201

      Nearly 40 years after hepatocyte transplantation was first used to treat an enzyme deficiency in animal studies, the potential therapeutic use of the hepatic cells still hasn't been fully realized. This month, “The AJT Report” takes a look at current efforts under way, along with the challenges researchers face. We also review new data on declining donor liver quality.

  2. Literature Watch

    1. Top of page
    2. The AJT Report
    3. Literature Watch
    4. Editorials
    5. Minireviews
    6. Meeting Report
    7. Original Articles
    8. Brief Communications
    9. Case Reports
    10. Reports From the CDC: MMWR
    11. Book Review
    12. Images in Transplantation
    13. Letter to the Editor
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      LITERATURE Watch Implications for transplantation (page 533)

      Anna Valujskikh and Jonathan S. Bromberg

      Article first published online: 25 FEB 2013 | DOI: 10.1111/ajt.12202

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      Several recent studies help define the molecular and cellular factors supporting bone marrow plasma cell survival and function, a topic highly relevant to transplantation, as therapies that efficiently eliminate mature B cells often do not affect donor-reactive alloantibody production.

  3. Editorials

    1. Top of page
    2. The AJT Report
    3. Literature Watch
    4. Editorials
    5. Minireviews
    6. Meeting Report
    7. Original Articles
    8. Brief Communications
    9. Case Reports
    10. Reports From the CDC: MMWR
    11. Book Review
    12. Images in Transplantation
    13. Letter to the Editor
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      Galectin-1, Immune Regulation and Liver Allograft Survival (pages 535–536)

      A. E. Morelli and A. W. Thomson

      Article first published online: 25 FEB 2013 | DOI: 10.1111/ajt.12092

      The article by Ye et al (page 569) suggests that the lectin galectin-1, which exhibits immune regulatory function, may be of potential therapeutic value to prevent liver allograft rejection.

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      TNFα, TGFβ, Pseudomonas and Classically Activated Macrophages Conspire to Reprogram the Airways in Obliterative Bronchiolitis (pages 537–538)

      D. C. Neujahr

      Article first published online: 17 JAN 2013 | DOI: 10.1111/ajt.12069

      A perfect storm of inflammatory signals and bacteria conspire to drive alveolar macrophages toward a phenotype capable of inducing small airway fibrosis in lung transplant recipients. See article by Borthwick et al on page 621.

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      Molecular Analysis of Renal Allograft Biopsies—More Than a Nice Toy for Researchers? (pages 539–540)

      H.-D. Volk, B. Sawitzki and P. Reinke

      Article first published online: 25 FEB 2013 | DOI: 10.1111/ajt.12081

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      This editorial discuss two papers (see pages 634 and 645) on molecular diagnosis of kidney transplant injury as an alternative to standard histopathological analysis, highlighting the broad range of opportunities as well as remaining needs influencing the adoption of these techniques into routine clinical practice.

  4. Minireviews

    1. Top of page
    2. The AJT Report
    3. Literature Watch
    4. Editorials
    5. Minireviews
    6. Meeting Report
    7. Original Articles
    8. Brief Communications
    9. Case Reports
    10. Reports From the CDC: MMWR
    11. Book Review
    12. Images in Transplantation
    13. Letter to the Editor
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      LIGHT/HVEM/LTβR Interaction as a Target for the Modulation of the Allogeneic Immune Response in Transplantation (pages 541–551)

      M.-L. del Rio, P. Schneider, C. Fernandez-Renedo, J.-A. Perez-Simon and J.-I. Rodriguez-Barbosa

      Article first published online: 28 JAN 2013 | DOI: 10.1111/ajt.12089

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      This review discusses how targeting the interaction of LIGHT with HVEM and/or LTbR using recombinant soluble decoy receptors or monoclonal antibodies may represent an innovative therapeutic intervention for the prevention and treatment of allograft rejection and promotion of donor-specific tolerance.

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      Bronchoalveolar Lavage as a Tool to Predict, Diagnose and Understand Bronchiolitis Obliterans Syndrome (pages 552–561)

      V. E. Kennedy, J. L. Todd and S. M. Palmer

      Article first published online: 28 JAN 2013 | DOI: 10.1111/ajt.12091

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      This minireview applies objective criteria to qualitatively rank the strength of associations between bronchoalveolar lavage parameters and bronchiolitis obliterans syndrome, facilitating a comprehensive and critical assessment of the last 20 years of literature in this field.

  5. Meeting Report

    1. Top of page
    2. The AJT Report
    3. Literature Watch
    4. Editorials
    5. Minireviews
    6. Meeting Report
    7. Original Articles
    8. Brief Communications
    9. Case Reports
    10. Reports From the CDC: MMWR
    11. Book Review
    12. Images in Transplantation
    13. Letter to the Editor
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      Precision Diagnostics in Transplantation: From Bench to Bedside (pages 562–568)

      M. Mengel, P. Campbell, H. Gebel, P. Randhawa, E. R. Rodriguez, R. Colvin, J. Conway, R. Hachem, P. F. Halloran, S. Keshavjee, P. Nickerson, C. Murphey, J. O'Leary, J. Reeve, K. Tinckam and E. F. Reed

      Article first published online: 27 DEC 2012 | DOI: 10.1111/j.1600-6143.2012.04344.x

      This report summarizes a meeting jointly organized by the Canadian Society of Transplantation and the American Society of Transplantation with a focus on recent advances in transplant diagnostics, introducing the significant potential of these technologies, but stressing the need for interdisciplinary collaboration to validate their true diagnostic precision.

  6. Original Articles

    1. Top of page
    2. The AJT Report
    3. Literature Watch
    4. Editorials
    5. Minireviews
    6. Meeting Report
    7. Original Articles
    8. Brief Communications
    9. Case Reports
    10. Reports From the CDC: MMWR
    11. Book Review
    12. Images in Transplantation
    13. Letter to the Editor
    1. Basic Science

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      Galectin-1 Prolongs Survival of Mouse Liver Allografts From Flt3L-Pretreated Donors (pages 569–579)

      Y. Ye, S. Yan, G. Jiang, L. Zhou, H. Xie, X. Xie, X. Yu, Y. Ding, J. Tian, Y. Dai and S. Zheng

      Article first published online: 28 JAN 2013 | DOI: 10.1111/ajt.12088

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      Galectin-1 prolongs survival of liver allografts from Flt3L-pretreated donors and ameliorates Flt3L-triggered liver allograft rejection. See editorial by Morelli and Thomson on page 535.

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      Allograft Outcomes in Outbred Mice (pages 580–588)

      D. K. Reichenbach, Q. Li, R. A. Hoffman, A. L. Williams, W. D. Shlomchik, D. M. Rothstein, A. J. Demetris and F. G. Lakkis

      Article first published online: 11 JAN 2013 | DOI: 10.1111/ajt.12056

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      Transplantation of heart allografts between outbred and inbred mice reveals a donor-dependent early graft injury phenotype mediated by complement and neutrophils, but also shows that outbred recipients are not resistant to allograft acceptance, and suggests that mechanisms other than inbreeding depression likely account for the relative ease of inducing tolerance in inbred mice.

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      Pretransplant Antithymocyte Globulin Has Increased Efficacy in Controlling Donor-Reactive Memory T Cells in Mice (pages 589–599)

      K. Ayasoufi, H. Yu, R. Fan, X. Wang, J. Williams and A. Valujskikh

      Article first published online: 17 JAN 2013 | DOI: 10.1111/ajt.12068

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      This study in a mouse cardiac allograft model demonstrates that administration of antithymocyte globulin one week prior to transplantation is more efficient in targeting preexisting donor-reactive memory T cells, inhibiting antidonor T cell responses, and prolonging heart allograft survival than the commonly used treatment at the time of transplantation.

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      Differential Effects of Pharmacological HIF Preconditioning of Donors Versus Recipients in Rat Cardiac Allografts (pages 600–610)

      M. A. I. Keränen, R. Tuuminen, S. Syrjälä, R. Krebs, G. Walkinshaw, L. A. Flippin, M. Arend, P. K. Koskinen, A. I. Nykänen and K. B. Lemström

      Article first published online: 17 JAN 2013 | DOI: 10.1111/ajt.12064

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      The authors report that pretreatment of cardiac allograft donors or recipients with the novel prolyl-hydroxylase inhibitor FG-4497 leads to divergent outcomes in a rat cardiac allograft transplantation model.

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      Cyclosporine A Drives a Th17- and Th2-Mediated Posttransplant Obliterative Airway Disease (pages 611–620)

      P. H. Lemaître, B. Vokaer, L.-M. Charbonnier, Y. Iwakura, K. A. Field, M. Estenne, M. Goldman, O. Leo, M. Remmelink and A. Le Moine

      Article first published online: 17 JAN 2013 | DOI: 10.1111/ajt.12067

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      This study demonstrates that cyclosporine a treatment unbalances T helper alloreactivity and favors Th2 and Th17 as coexisting pathways mediating chronic rejection of heterotopic tracheal allografts.

    6. Clinical Science

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      TNFα From Classically Activated Macrophages Accentuates Epithelial to Mesenchymal Transition in Obliterative Bronchiolitis (pages 621–633)

      L. A. Borthwick, P. A. Corris, R. Mahida, A. Walker, A. Gardner, M. Suwara, G. E. Johnson, E. J. Moisey, M. Brodlie, C. Ward, J. D. Perry, A. De Soyza, D. A. Mann and A. J. Fisher

      Article first published online: 17 JAN 2013 | DOI: 10.1111/ajt.12065

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      This study demonstrates that TNFα released from classically activated macrophages can accentuate TGF-β1-driven epithelial to mesenchymal transition in bronchial epithelial cells isolated from lung transplant patients and that anti-TNFα treatment improves forced expiratory volume in 1 second and 6 minute walk distances in a pilot therapeutic intervention in patients with bronchiolitis obliterans syndrome. See editorial by Neujahr on page 537

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      Kidney Transplants With Progressing Chronic Diseases Express High Levels of Acute Kidney Injury Transcripts (pages 634–644)

      K. S. Famulski, J. Reeve, D. G. de Freitas, C. Kreepala, J. Chang and P. F. Halloran

      Article first published online: 28 JAN 2013 | DOI: 10.1111/ajt.12080

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      The transcripts typical of acute kidney injury, defined in kidney transplants with early reversible injury, are also expressed in biopsies of late transplants with progressive diseases as a reflection of parenchymal distress, indicating that progression in failing kidneys is not due to fibrosis but to ongoing parenchymal injury. See editorial by Volk et al on page 539.

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      Molecular Diagnosis of T Cell-Mediated Rejection in Human Kidney Transplant Biopsies (pages 645–655)

      J. Reeve, J. Sellarés, M. Mengel, B. Sis, A. Skene, L. Hidalgo, D. G. de Freitas, K. S. Famulski and P. F. Halloran

      Article first published online: 28 JAN 2013 | DOI: 10.1111/ajt.12079

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      The authors report on the development of a microarray-based diagnostic classifier to assign T cell-mediated rejection scores in kidney transplant biopsies that correlated with infiltration, tubulitis, and histologic diagnoses, and could help in the diagnosis of cases where histology is inaccurate or ambiguous. See editorial by Volk et al on page 539.

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      Subclinical Epstein–Barr Virus Viremia Among Adult Renal Transplant Recipients: Incidence and Consequences (pages 656–662)

      J. Bamoulid, C. Courivaud, A. Coaquette, J.-M. Chalopin, E. Gaiffe, P. Saas and D. Ducloux

      Article first published online: 17 JAN 2013 | DOI: 10.1111/ajt.12009

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      Subclinical Epstein-Barr virus infection is frequent after kidney transplantation and reflects overimmunosuppression.

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      Complement Genes Strongly Predict Recurrence and Graft Outcome in Adult Renal Transplant Recipients with Atypical Hemolytic and Uremic Syndrome (pages 663–675)

      M. Le Quintrec, J. Zuber, B. Moulin, N. Kamar, M. Jablonski, A. Lionet, V. Chatelet, C. Mousson, G. Mourad, F. Bridoux, E. Cassuto, C. Loirat, E. Rondeau, M. Delahousse and V. Frémeaux-Bacchi

      Article first published online: 28 JAN 2013 | DOI: 10.1111/ajt.12077

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      This study highlights that characterization of complement genetic abnormalities predicts the risk of recurrence-related graft loss.

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      Urine High and Low Molecular Weight Proteins One-Year Post-Kidney Transplant: Relationship to Histology and Graft Survival (pages 676–684)

      H. Amer, J. C. Lieske, A. D. Rule, W. K. Kremers, T. S. Larson, C. R. Franco Palacios, M. D. Stegall and F. G. Cosio

      Article first published online: 15 FEB 2013 | DOI: 10.1111/ajt.12044

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      This study examines several urinary proteins derived from kidney transplant recipients one year after transplantation and finds that retinol-binding protein provides additional prognostic information beyond urinary albumin and graft histology.

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      Hypocomplementemia in Kidney Transplant Recipients: Impact on the Risk of Infectious Complications (pages 685–694)

      M. Fernández-Ruiz, F. López-Medrano, P. Varela-Peña, J. M. Morales, A. García-Reyne, R. San Juan, C. Lumbreras, D. Lora-Pablos, N. Polanco, A. Andrés, E. Paz-Artal and J. M. Aguado

      Article first published online: 11 JAN 2013 | DOI: 10.1111/ajt.12055

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      In a broad cohort of kidney transplant recipients, the authors find that the presence of C3 hypocomplementemia at months 1 and 6 correlates with the subsequent occurrence of infectious complications, thus opening new opportunities in the design of simple, clinically applicable strategies of immune monitoring in these patients.

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      Rate of Renal Graft Function Decline After One Year Is a Strong Predictor of All-Cause Mortality (pages 695–706)

      O. Moranne, N. Maillard, C. Fafin, L. Thibaudin, E. Alamartine and C. Mariat

      Article first published online: 11 JAN 2013 | DOI: 10.1111/ajt.12053

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      In an incipient cohort of 488 transplant kidney recipients with a mean follow-up of 12 years, inulin-derived GFR slope beyond the first anniversary of transplantation appears to be an independent predictor of all-cause mortality; one that is stronger than a fixed GFR value measured at one year posttransplant.

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      Kidney Function Endpoints in Kidney Transplant Trials: A Struggle for Power (pages 707–713)

      A. Ibrahim, A. X. Garg, G. A. Knoll, A. Akbari and C. A. White

      Article first published online: 11 JAN 2013 | DOI: 10.1111/ajt.12050

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      This systematic review of the NIH clinical trials registry reveals that only a minority of ongoing trials have adequate statistical power to detect between group differences in graft function.

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      Racial/Ethnic Differences in Cancer Risk After Kidney Transplantation (pages 714–720)

      E. C. Hall, D. L. Segev and E. A. Engels

      Article first published online: 17 JAN 2013 | DOI: 10.1111/ajt.12066

      Among US kidney recipients, cancer incidence varies by race/ethnicity, reflecting both background differences in the general population and, for some cancers, differing effects of transplantation on risk.

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      Minimally Invasive Robotic Kidney Transplantation for Obese Patients Previously Denied Access to Transplantation (pages 721–728)

      J. Oberholzer, P. Giulianotti, K. K. Danielson, M. Spaggiari, L. Bejarano-Pineda, F. Bianco, I. Tzvetanov, S. Ayloo, H. Jeon, R. Garcia-Roca, J. Thielke, I. Tang, S. Akkina, B. Becker, K. Kinzer, A. Patel and E. Benedetti

      Article first published online: 25 FEB 2013 | DOI: 10.1111/ajt.12078

      The authors report results on a new robotic kidney transplantation technique for obese patients that has comparable patient outcomes compared to an open procedure.

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      MicroRNA Signature at the Time of Clinical HCV Recurrence Associates With Aggressive Fibrosis Progression Post-Liver Transplantation (pages 729–737)

      R. C. Gehrau, V. R. Mas, F. G. Villamil, C. I. Dumur, N. K. Mehta, J. L. Suh and D. G. Maluf

      Article first published online: 11 JAN 2013 | DOI: 10.1111/ajt.12047

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      The authors use tissue microarray analyses to determine a 9-microRNA signature able to identify hepatitis C patients at greater risk of severe disease recurrence and worse outcome post-liver transplantation.

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      Pretransplant Interferon-γ Secretion by CMV-Specific CD8+ T Cells Informs the Risk of CMV Replication After Transplantation (pages 738–745)

      S. Cantisán, R. Lara, M. Montejo, J. Redel, A. Rodríguez-Benot, J. Gutiérrez-Aroca, M. González-Padilla, L. Bueno, A. Rivero, R. Solana and J. Torre-Cisneros

      Article first published online: 11 JAN 2013 | DOI: 10.1111/ajt.12049

      One-third of cytomegalovirus-seropositive solid organ transplant candidates do not have pretransplant detectable interferon-gamma production by cytomegalovirus-specific CD8+ T cells and are at higher risk of posttransplant cytomegalovirus replication, indicating that assessment of pretransplant interferon-gamma production might contribute to a novel design of the antiviral prevention strategy.

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      Frequency and Determinants of Pregnancy-Induced Child-Specific Sensitization (pages 746–753)

      G. Hönger, I. Fornaro, C. Granado, J.-M. Tiercy, I. Hösli and S. Schaub

      Article first published online: 11 JAN 2013 | DOI: 10.1111/ajt.12048

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      Using current technology, pregnancy-induced sensitization shortly after full-term delivery is present in over 45% of mothers and depends on the number of live births, specific paternal HLA-antigens, and the mother's own HLA-phenotype.

  7. Brief Communications

    1. Top of page
    2. The AJT Report
    3. Literature Watch
    4. Editorials
    5. Minireviews
    6. Meeting Report
    7. Original Articles
    8. Brief Communications
    9. Case Reports
    10. Reports From the CDC: MMWR
    11. Book Review
    12. Images in Transplantation
    13. Letter to the Editor
    1. You have free access to this content
      Early Plasma Soluble Receptor for Advanced Glycation End-Product Levels Are Associated With Bronchiolitis Obliterans Syndrome (pages 754–759)

      R. J. Shah, S. L. Bellamy, J. C. Lee, E. Cantu, J. M. Diamond, N. Mangalmurti, S. M. Kawut, L. B. Ware and J. D. Christie

      Article first published online: 17 JAN 2013 | DOI: 10.1111/ajt.12062

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      This retrospective cohort study identifies an association between plasma sRAGE levels measured 6 and 24 hours after lung transplantation and increased risk of bronchiolitis obliterans syndrome, potentially providing an important link between injury early after transplantation and later complications.

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      Conversion From Twice-Daily Tacrolimus to Once-Daily Extended Release Tacrolimus (LCPT): The Phase III Randomized MELT Trial (pages 760–769)

      S. Bunnapradist, K. Ciechanowski, P. West-Thielke, S. Mulgaonkar, L. Rostaing, B. Vasudev, K. Budde and on behalf of the MELT investigators

      Article first published online: 21 DEC 2012 | DOI: 10.1111/ajt.12035

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      This phase III noninferiority conversion trial in stable renal transplant recipients demonstrates that a novel extended-release once-daily tacrolimus formulation is noninferior to tacrolimus twice-daily in efficacy failure rates, has a similar safety profile, and requires lower doses to achieve target trough levels.

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      Infections Following Facial Composite Tissue Allotransplantation—Single Center Experience and Review of the Literature (pages 770–779)

      B. M. Knoll, S. P. Hammond, S. Koo, N. C. Issa, S. G. Tullius, L. R. Baden, B. Pomahac and F. M. Marty

      Article first published online: 27 DEC 2012 | DOI: 10.1111/ajt.12013

      The authors report a detailed experience of the infectious complications following facial composite tissue allotransplantation at their center in four patients followed for over a year, summarize the published literature on this topic, and discuss strategies to address infectious diseases risks in this emerging patient population.

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      Preliminary Marked Increase in the National Organ Donation Rate in Israel Following Implementation of a New Organ Transplantation Law (pages 780–785)

      J. Lavee, T. Ashkenazi, A. Stoler, J. Cohen and R. Beyar

      Article first published online: 27 DEC 2012 | DOI: 10.1111/ajt.12001

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      The authors report preliminary results following implementation of a new Organ Transplantation Law and Brain-Respiratory Death Law in Israel, showing a significant increase in national deceased and living organ donation rates combined with marked decrease in transplant tourism.

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      Acute Calcineurin Inhibitor Overdose: Analysis of Cases Reported to a National Poison Center Between 1995 and 2011 (pages 786–795)

      A. Ceschi, C. Rauber-Lüthy, H. Kupferschmidt, N. R. Banner, M. Ansari, S. Krähenbühl and A. B. Taegtmeyer

      Article first published online: 27 DEC 2012 | DOI: 10.1111/j.1600-6143.2012.04347.x

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      This study investigates 28 cases of overdose with the calcineurin inhibitors cyclosporine and tacrolimus, and shows that acute enteral overdoses are generally well tolerated and respond to enteral decontamination measures that reduce drug absorption, but that acute intravenous overdoses are less well tolerated.

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      Improving Transplant Patient Safety Through Pharmacist Discharge Medication Reconciliation (pages 796–801)

      C. R. Musgrave, N. A. Pilch, D. J. Taber, H. B. Meadows, J. W. McGillicuddy, K. D. Chavin and P. K. Baliga

      Article first published online: 17 JAN 2013 | DOI: 10.1111/ajt.12070

      This study demonstrates that abdominal transplant recipients experience high rates of medication errors at the time of discharge, and integrating a pharmacist into the discharge medication reconciliation process with follow-up in the transplant clinic significantly reduces these errors.

  8. Case Reports

    1. Top of page
    2. The AJT Report
    3. Literature Watch
    4. Editorials
    5. Minireviews
    6. Meeting Report
    7. Original Articles
    8. Brief Communications
    9. Case Reports
    10. Reports From the CDC: MMWR
    11. Book Review
    12. Images in Transplantation
    13. Letter to the Editor
    1. You have free access to this content
      HLA-DRB1 Typing by Micro-Bead Array Assay Identifies the Origin of Early Lymphoproliferative Disorder in a Heart Transplant Recipient (pages 802–807)

      M. Fedrigo, F. Poli, G. Esposito, G. Feltrin, G. Toscano, C. d'Agostino, B. Schiavon, G. Gerosa, A. Amadori, M. Valente, G. Thiene and A. Angelini

      Article first published online: 17 JAN 2013 | DOI: 10.1111/ajt.12063

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      The authors report the application of HLA typing technique to identify neoplastic donor/recipient cell origin from a tumor mass infiltrating the coronary artery of a heart allograft.

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      Posterior Reversible Encephalopathy Syndrome Independently Associated With Tacrolimus and Sirolimus After Multivisceral Transplantation (pages 808–810)

      A. S. Barbas, A. S. Rege, A. W. Castleberry, J. Gommer, M. J. Ellis, T. V. Brennan, B. H. Collins, A. E. Martin, K. V. Ravindra, D. S. Vikraman and D. L. Sudan

      Article first published online: 17 JAN 2013 | DOI: 10.1111/ajt.12061

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      This case report describes a multivisceral transplant recipient who developed recurrent posterior reversible encephalopathy syndrome independently associated with tacrolimus and subsequently sirolimus.

  9. Reports From the CDC: MMWR

    1. Top of page
    2. The AJT Report
    3. Literature Watch
    4. Editorials
    5. Minireviews
    6. Meeting Report
    7. Original Articles
    8. Brief Communications
    9. Case Reports
    10. Reports From the CDC: MMWR
    11. Book Review
    12. Images in Transplantation
    13. Letter to the Editor
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      Early Estimates of Seasonal Influenza Vaccine Effectiveness—United States, January 2013 (pages 811–814)

      Article first published online: 25 FEB 2013 | DOI: 10.1111/ajt.12203

      Influenza vaccination is recommended for transplant candidates and recipients, but the efficacy of the vaccine is estimated to be approximately 60%. Consequently, antiviral treatment is recommended for symptomatic patients suspected of having influenza regardless of vaccination status.

  10. Book Review

    1. Top of page
    2. The AJT Report
    3. Literature Watch
    4. Editorials
    5. Minireviews
    6. Meeting Report
    7. Original Articles
    8. Brief Communications
    9. Case Reports
    10. Reports From the CDC: MMWR
    11. Book Review
    12. Images in Transplantation
    13. Letter to the Editor
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  11. Images in Transplantation

    1. Top of page
    2. The AJT Report
    3. Literature Watch
    4. Editorials
    5. Minireviews
    6. Meeting Report
    7. Original Articles
    8. Brief Communications
    9. Case Reports
    10. Reports From the CDC: MMWR
    11. Book Review
    12. Images in Transplantation
    13. Letter to the Editor
    1. CME

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  12. Letter to the Editor

    1. Top of page
    2. The AJT Report
    3. Literature Watch
    4. Editorials
    5. Minireviews
    6. Meeting Report
    7. Original Articles
    8. Brief Communications
    9. Case Reports
    10. Reports From the CDC: MMWR
    11. Book Review
    12. Images in Transplantation
    13. Letter to the Editor
    1. You have free access to this content
      Meningococcal Sepsis Complicating Eculizumab Treatment Despite Prior Vaccination (pages 819–820)

      G. H. Struijk, A. H. M. Bouts, G. T. Rijkers, E. A. C. Kuin, I. J. M. ten Berge and F. J. Bemelman

      Article first published online: 7 JAN 2013 | DOI: 10.1111/ajt.12032

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      Pancreas Transplantation From Controlled Donation After Circulatory Death Donors (page 823)

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