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American Journal of Transplantation

Cover image for Vol. 13 Issue 8

August 2013

Volume 13, Issue 8

Pages 1941–2231

  1. The AJT Report

    1. Top of page
    2. The AJT Report
    3. Literature Watch
    4. Editorials
    5. Special Article
    6. Original Articles
    7. Brief Communications
    8. Case Reports
    9. Reports From the CDC: MMWR
    10. Images in Transplantation
    11. Letters to the Editor
    12. Errata
    1. You have free access to this content
      The AJT Report (pages 1941–1942)

      Sue Pondrom

      Article first published online: 26 JUL 2013 | DOI: 10.1111/ajt.12418

      This spring, a district court judge ordered that two children receive increased priority for lungs from adolescent and adult donors. We explore what this ruling might mean for the future of OPTN policy. Also in this issue, we look at a new Health and Human Services guideline designed to minimize disease transmission in organ transplantation.

  2. Literature Watch

    1. Top of page
    2. The AJT Report
    3. Literature Watch
    4. Editorials
    5. Special Article
    6. Original Articles
    7. Brief Communications
    8. Case Reports
    9. Reports From the CDC: MMWR
    10. Images in Transplantation
    11. Letters to the Editor
    12. Errata
    1. You have free access to this content
      Literature Watch Implications for transplantation (page 1943)

      Anita S. Chong and Jonathan S. Bromberg

      Article first published online: 26 JUL 2013 | DOI: 10.1111/ajt.12419

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      Several recent reports hypothesize a link between the microbiota within transplanted organs and the alloreactive responses elicited. This month, we review new evidence for infl ammasome activation mediating this link.

  3. Editorials

    1. Top of page
    2. The AJT Report
    3. Literature Watch
    4. Editorials
    5. Special Article
    6. Original Articles
    7. Brief Communications
    8. Case Reports
    9. Reports From the CDC: MMWR
    10. Images in Transplantation
    11. Letters to the Editor
    12. Errata
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      An Orchestrated Dance Between Differing Regulatory T Cell Phenotypes in Allograft Tolerance (pages 1945–1946)

      R. G. Gill

      Article first published online: 26 JUL 2013 | DOI: 10.1111/ajt.12336

      While the field has focused largely on Foxp3+ Tregs as mediators of regulatory allograft tolerance, a new study provides evidence that a ‘division of labor’ can occur between Tregs and IL-10-producing Tr1 cells in which each regulatory cell type can be required during differing phases of the tolerogenic response. See article by Gagliani et al on page 1963.

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      Transplant Wobegon: Where All the Organs Are Used, All the Patients Are Transplanted, and All Programs Are Above Average (pages 1947–1948)

      D. A. Axelrod, J. Snyder and B. Kasiske

      Article first published online: 26 JUL 2013 | DOI: 10.1111/ajt.12327

      The evaluation of transplant center performance requires innovative solutions to improve accuracy and promote the best interests of patients. See article by Massie and Segev on page 2044.

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      Deceased Donor Liver Allocation: Cutting the Gordian Knot (pages 1949–1950)

      H. Yeh and L. Hunsicker

      Article first published online: 26 JUL 2013 | DOI: 10.1111/ajt.12302

      The authors discuss the implications of a novel approach to deceased donor liver distribution that designs new OPTN regions by combining low and high organ availability donation service areas. See article by Gentry et al on page 2052.

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      In Search of Perfection (pages 1951–1952)

      H. M. Gebel and R. A. Bray

      Article first published online: 9 JUL 2013 | DOI: 10.1111/ajt.12335

      Solid phase HLA antibody detection assays are quite good, and though imperfect, they convey valuable information. See article by Gombos et al on page 2075.

  4. Special Article

    1. Top of page
    2. The AJT Report
    3. Literature Watch
    4. Editorials
    5. Special Article
    6. Original Articles
    7. Brief Communications
    8. Case Reports
    9. Reports From the CDC: MMWR
    10. Images in Transplantation
    11. Letters to the Editor
    12. Errata
    1. You have free access to this content
      Excerpt From PHS Guideline for Reducing HIV, HBV and HCV Transmission Through Organ Transplantation (pages 1953–1962)

      D. L. Seem, I. Lee, C. A. Umscheid and M. J. Kuehnert

      Article first published online: 26 JUL 2013 | DOI: 10.1111/ajt.12386

      This excerpt of a recently released Public Health Service guideline summarizes recommendations for 1) identification of donor risk factors for infection; 2) screening and testing of living and deceased donors; 3) informed consent discussions with transplant candidates; 4) recipient testing pre- and posttransplantation; 5) collection and storage of blood specimens for future investigation; 6) reporting and tracking of infected donors and recipients; and 7) further study where data are lacking.

  5. Original Articles

    1. Top of page
    2. The AJT Report
    3. Literature Watch
    4. Editorials
    5. Special Article
    6. Original Articles
    7. Brief Communications
    8. Case Reports
    9. Reports From the CDC: MMWR
    10. Images in Transplantation
    11. Letters to the Editor
    12. Errata
    1. Basic Science

      You have full text access to this OnlineOpen article
      Transplant Tolerance to Pancreatic Islets Is Initiated in the Graft and Sustained in the Spleen (pages 1963–1975)

      N. Gagliani, T. Jofra, A. Valle, A. Stabilini, C. Morsiani, S. Gregori, S. Deng, D. M. Rothstein, M. Atkinson, M. Kamanaka, R. A. Flavell, M. G. Roncarolo and M. Battaglia

      Article first published online: 8 JUL 2013 | DOI: 10.1111/ajt.12333

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      In a model of allogeneic pancreatic islet transplantation, Foxp3+ Treg cells exert their regulatory function within the allograft and initiate engraftment locally and in a non-antigen-specific manner, whereas CD4+CD25- T cells, which contain IL-10-producing Tr1 cells, act from the spleen and are key to the maintenance of long-term tolerance. See editorial by Gill on page 1945.

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      ASKP1240, a Fully Human Anti-CD40 Monoclonal Antibody, Prolongs Pancreatic Islet Allograft Survival in Nonhuman Primates (pages 1976–1988)

      M. Watanabe, K. Yamashita, T. Suzuki, H. Kamachi, D. Kuraya, Y. Koshizuka, M. Ogura, T. Yoshida, T. Aoyagi, D. Fukumori, T. Shimamura, K. Okimura, K. Maeta, T. Miura, F. Sakai and S. Todo

      Article first published online: 10 JUL 2013 | DOI: 10.1111/ajt.12330

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      The authors find that the blockade of CD40 by ASKP1240 suppresses cellular and humoral alloimmune responses, prolongs pancreatic islet allograft survival in nonhuman primates, and might be a promising approach for immunosuppression in clinical pancreatic islet transplantation.

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      Regulatory Dendritic Cell Infusion Prolongs Kidney Allograft Survival in Nonhuman Primates (pages 1989–2005)

      M. B. Ezzelarab, A. F. Zahorchak, L. Lu, A. E. Morelli, G. Chalasani, A. J. Demetris, F. G. Lakkis, M. Wijkstrom, N. Murase, A. Humar, R. Shapiro, D. K. C. Cooper and A. W. Thomson

      Article first published online: 11 JUN 2013 | DOI: 10.1111/ajt.12310

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      Infusion of regulatory dendritic cells, in combination with costimulation blockade and rapamycin, prolongs renal allograft survival and regulates donor-specific memory T cells in a clinically relevant nonhuman primate model.

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      Xenon Treatment Protects Against Cold Ischemia Associated Delayed Graft Function and Prolongs Graft Survival in Rats (pages 2006–2018)

      H. Zhao, H. R. Watts, M. Chong, H. Huang, C. Tralau-Stewart, P. H. Maxwell, M. Maze, A. J. T. George and D. Ma

      Article first published online: 24 MAY 2013 | DOI: 10.1111/ajt.12293

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      Xenon treatment attenuates delayed kidney graft function and prolongs graft survival in rats.

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      Donor Simvastatin Treatment Prevents Ischemia-Reperfusion and Acute Kidney Injury by Preserving Microvascular Barrier Function (pages 2019–2034)

      R. Tuuminen, A. I. Nykänen, P. Saharinen, P. Gautam, M. A. I. Keränen, R. Arnaudova, E. Rouvinen, H. Helin, R. Tammi, K. Rilla, R. Krebs and K. B. Lemström

      Article first published online: 14 JUN 2013 | DOI: 10.1111/ajt.12315

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      Single-dose donor simvastatin treatment stabilizes the microvasculature during rat kidney allograft ischemia reperfusion injury and inhibits innate and adaptive immune responses.

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      PI3Kδ Inhibition Augments the Efficacy of Rapamycin in Suppressing Proliferation of Epstein−Barr Virus (EBV)+ B Cell Lymphomas (pages 2035–2043)

      S. Furukawa, L. Wei, S. M. Krams, C. O. Esquivel and O. M. Martinez

      Article first published online: 10 JUL 2013 | DOI: 10.1111/ajt.12328

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      The authors demonstrate that targeting PI3Kδ with a small molecule inhibitor can enhance the antiproliferative effect of mTOR inhibitors in the Epstein-Barr virus positive B cell lymphomas associated with posttransplant lymphoproliferative disorder.

    7. Clinical Science

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      Rates of False Flagging Due to Statistical Artifact in CMS Evaluations of Transplant Programs: Results of a Stochastic Simulation (pages 2044–2051)

      A. B. Massie and D. L. Segev

      Article first published online: 26 JUL 2013 | DOI: 10.1111/ajt.12325

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      This simulation study of CMS evaluations of transplant programs shows that statistical noise plays a large role in determining which centers are flagged for poor outcomes. See editorial by Axelrod et al on page 1947.

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      Addressing Geographic Disparities in Liver Transplantation Through Redistricting (pages 2052–2058)

      S. E. Gentry, A. B. Massie, S. W. Cheek, K. L. Lentine, E. H. Chow, C. E. Wickliffe, N. Dzebashvili, P. R. Salvalaggio, M. A. Schnitzler, D. A. Axelrod and D. L. Segev

      Article first published online: 9 JUL 2013 | DOI: 10.1111/ajt.12301

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      Full regional sharing of liver offers within the existing regions would paradoxically increase geographic inequity, but using optimal redistricting to design novel regions would make liver allocation more geographically equitable. See editorial by Yeh and Hunsicker on page 1949.

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      Social Media and Organ Donor Registration: The Facebook Effect (pages 2059–2065)

      A. M. Cameron, A. B. Massie, C. E. Alexander, B. Stewart, R. A. Montgomery, N. R. Benavides, G. D. Fleming and D. L. Segev

      Article first published online: 18 JUN 2013 | DOI: 10.1111/ajt.12312

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      The authors report that an immediate increase in online donation registration was seen around the country following a small change in the platform of a large online social network that allowed for declaration and sharing of one's organ donor status.

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      Disparities in Policies, Practices and Rates of Pediatric Kidney Transplantation in Europe (pages 2066–2074)

      J. Harambat, K. J. van Stralen, F. Schaefer, R. Grenda, A. Jankauskiene, M. Kostic, M.-A. Macher, H. Maxwell, Z. Puretic, A. Raes, J. Rubik, S. S. Sørensen, Ü. Toots, R. Topaloglu, B. Tönshoff, E. Verrina and K. J. Jager

      Article first published online: 29 MAY 2013 | DOI: 10.1111/ajt.12288

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      The results of this study, combining data from a European Registry with a survey of 38 European countries about allocation policies, practices, and rates of pediatric kidney transplantation, show that considerable disparity exists between countries.

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      Influence of Test Technique on Sensitization Status of Patients on the Kidney Transplant Waiting List (pages 2075–2082)

      P. Gombos, G. Opelz, S. Scherer, C. Morath, M. Zeier, P. Schemmer and C. Süsal

      Article first published online: 10 JUL 2013 | DOI: 10.1111/ajt.12332

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      The results of this study on the kidney waiting list suggest that denial of donor kidneys to recipients based on HLA antibody specificities detected exclusively in the single-antigen-bead assay is not justified. See editorial by Gebel and Bray on page 1951.

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      The Survival Benefit of Kidney Transplantation in Obese Patients (pages 2083–2090)

      J. S. Gill, J. Lan, J. Dong, C. Rose, E. Hendren, O. Johnston and J. Gill

      Article first published online: 25 JUL 2013 | DOI: 10.1111/ajt.12331

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      In this US Renal Data System analysis, the authors show that most obese patients derive a similar survival benefit from transplantation as nonobese patients, but the survival benefit is lower in patients with body mass index ≥ 40 kg/m2, and uncertain in black recipients with body mass index ≥ 40 kg/m2 and black recipients with body mass index of 35.0–39.9 kg/m2 who received expanded criteria donor transplants.

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      Frailty and Early Hospital Readmission After Kidney Transplantation (pages 2091–2095)

      M. A. McAdams-DeMarco, A. Law, M. L. Salter, E. Chow, M. Grams, J. Walston and D. L. Segev

      Article first published online: 3 JUN 2013 | DOI: 10.1111/ajt.12300

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      In a prospective longitudinal cohort study of kidney transplant recipients, the authors find that frailty was a strong predictor of hospital readmission within 30 days of transplantation, improving risk prediction above and beyond registry-based predictors.

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      Association Between Steroid Dosage and Death With a Functioning Graft After Kidney Transplantation (pages 2096–2105)

      G. Opelz and B. Döhler

      Article first published online: 10 JUN 2013 | DOI: 10.1111/ajt.12313

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      In this retrospective registry analysis of kidney transplants, maintenance steroid dose shows a significant association with death due to infection or cardiovascular disease even in patients with good graft outcome in whom steroid treatment would appear to be unnecessary.

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      Increased Metallothionein Expression Reflects Steroid Resistance in Renal Allograft Recipients (pages 2106–2118)

      N. V. Rekers, I. M. Bajema, M. J. K. Mallat, J. D. H. Anholts, Y. J. H. de Vaal, M. Zandbergen, G. W. Haasnoot, E. W. van Zwet, J. W. de Fijter, F. H. J. Claas and M. Eikmans

      Article first published online: 13 JUN 2013 | DOI: 10.1111/ajt.12314

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      The authors demonstrate that resistance to steroid treatment during acute renal allograft rejection is associated with high intragraft expression of zinc-regulating metallothioneins, which may diminish the zinc-requiring anti-infl ammatory effect of the glucocorticoid receptor.

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      CMV Infection in the Donor and Increased Kidney Graft Loss: Impact of Full HLA-I Mismatch and Posttransplantation CD8+ Cell Reduction (pages 2119–2129)

      P. Gatault, J-M. Halimi, C. Forconi, G. Thibault, C. Barbet, E. Mérieau, C. Gaudy-Graffin, J-F. Marlière, A. Goudeau, F. Bruyère, Y. Lebranchu, M. Büchler and C. Baron

      Article first published online: 3 JUN 2013 | DOI: 10.1111/ajt.12298

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      This large retrospective study shows that positive CMV serostatus of recipient and full HLA class I mismatching are the main determinants of poor graft outcome associated with CMV seropositivity of donor.

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      Donor Surfactant Protein D (SP-D) Polymorphisms Are Associated With Lung Transplant Outcome (pages 2130–2136)

      B. Aramini, C. Kim, S. DiAngelo, E. Petersen, D.J. Lederer, L. Shah, H. Robbins, J. Floros, S. M. Arcasoy, J. R. Sonett and F. D'Ovidio

      Article first published online: 10 JUL 2013 | DOI: 10.1111/ajt.12326

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      This study follows principles of Mendelian randomization to show that polymorphisms of the donor lung innate immunity molecule surfactant protein SP-D predict recipient post—lung transplant development of chronic lung allograft dysfunction and survival.

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      Epidemiology and Outcomes of Deep Surgical Site Infections Following Lung Transplantation (pages 2137–2145)

      R. K. Shields, C. J. Clancy, L. R. Minces, N. Shigemura, E. J. Kwak, F. P. Silveira, R. C. Abdel-Massih, J. K. Bhama, C. A. Bermudez, J. M. Pilewski, M. Crespo, Y. Toyoda and M. H. Nguyen

      Article first published online: 24 MAY 2013 | DOI: 10.1111/ajt.12292

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      This study demonstrates that deep surgical site infections are uncommon but important complications of lung transplantation because of their diverse microbiology and association with prolonged hospitalizations and increased mortality.

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      Primary Cutaneous Posttransplant Lymphoproliferative Disorders in Solid Organ Transplant Recipients: A Multicenter European Case Series (pages 2146–2153)

      D. Seçkin, S. Barete, S. Euvrard, C. Francès, J. Kanitakis, A. Geusau, V. del Marmol, C. A. Harwood, C. M. Proby, I. Ali, A. T. Güleç, E. Durukan, C. Lebbé, M. Alaibac, E. Laffitte, S. Cooper, J. N. Bouwes Bavinck, G. M. Murphy, C. Ferrándiz, C. Mørk, P. Cetkovská, W. Kempf and G. F. L. Hofbauer

      Article first published online: 29 MAY 2013 | DOI: 10.1111/ajt.12281

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      This case series suggests that primary cutaneous posttransplant lymphoproliferative disorders of T cell origin are more common than those of B cell origin, the spectrum of primary cutaneous T cell lymphoma in organ transplant recipients is similar to that in the general population, the prognosis of posttransplant primary cutaneous CD30+ lymphoproliferative disorders is worse than its counterpart in the immunocompetent population, and EBV-associated cutaneous B cell lymphoproliferative disorders predominate in organ transplant recipients.

  6. Brief Communications

    1. Top of page
    2. The AJT Report
    3. Literature Watch
    4. Editorials
    5. Special Article
    6. Original Articles
    7. Brief Communications
    8. Case Reports
    9. Reports From the CDC: MMWR
    10. Images in Transplantation
    11. Letters to the Editor
    12. Errata
    1. You have free access to this content
      Pretreatment of Donor Islets With the Na+/Ca2+ Exchanger Inhibitor Improves the Efficiency of Islet Transplantation (pages 2154–2160)

      T. Mera, T. Itoh, S. Kita, S. Kodama, D. Kojima, H. Nishinakamura, K. Okamoto, M. Ohkura, J. Nakai, T. Iyoda, T. Iwamoto, T. Matsuda, A. Baba, K. Omori, J. Ono, H. Watarai, M. Taniguchi and Y. Yasunami

      Article first published online: 7 JUN 2013 | DOI: 10.1111/ajt.12306

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      The early loss of transplanted mouse and human islets is prevented by the pretreatment of donor islets with the Na+/Ca2+ exchanger inhibitor in mice.

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      Vascularized Osteomyocutaneous Allografts Are Permissive to Tolerance by Induction-Based Immunomodulatory Therapy (pages 2161–2168)

      C. H. Lin, W. Zhang, T. W. Ng, D. Zhang, J. Jiang, B. Pulikkottil, F. Lakkis, V. S. Gorantla, W. P. A. Lee, G. Brandacher and X. X. Zheng

      Article first published online: 29 MAY 2013 | DOI: 10.1111/ajt.12275

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      This study demonstrates that vascularized osteomyocutaneous allografts are permissive to tolerance by inductionbased immunomodulatory therapy, and ex vivo alloantigen-induced CD4+ T cell—derived DN Tregs may provide an opportunity to develop novel strategies for transplant tolerance.

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      Ex Vivo-Expanded Cynomolgus Macaque Regulatory T Cells Are Resistant to Alemtuzumab-Mediated Cytotoxicity (pages 2169–2178)

      E. M. Dons, G. Raimondi, H. Zhang, A. F. Zahorchak, J. K. Bhama, L. Lu, M. Ezzelarab, J. N. M. Ijzermans, D. K. C. Cooper and A. W. Thomson

      Article first published online: 1 MAY 2013 | DOI: 10.1111/ajt.12248

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      This study shows that ex vivo-expanded cynomolgus monkey regulatory T cells downregulate CD52 and are not killed by alemtuzumab, suggesting they can be infused after lymphocyte depletion, without destruction by residual antibody.

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      Eculizumab Improves Posttransplant Thrombotic Microangiopathy Due to Antiphospholipid Syndrome Recurrence but Fails to Prevent Chronic Vascular Changes (pages 2179–2185)

      G. Canaud, N. Kamar, D. Anglicheau, L. Esposito, M. Rabant, L.-H. Noël, C. Guilbeau-Frugier, R. Sberro-Soussan, A. Del Bello, F. Martinez, J. Zuber, L. Rostaing and C. Legendre

      Article first published online: 13 JUN 2013 | DOI: 10.1111/ajt.12319

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      In this study, the authors report successful treatment with eculizumab in patients with posttransplant thrombotic microangiopathy related to antiphospholipid syndrome resistant to plasmapheresis, and explore complement deposition in associated biopsies.

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      Deceased Organ Donor Screening for HIV, Hepatitis B, and Hepatitis C Viruses: A Survey of Organ Procurement Organization Practices (pages 2186–2190)

      N. Theodoropoulos, A. Jaramillo, D. P. Ladner and M. G. Ison

      Article first published online: 24 MAY 2013 | DOI: 10.1111/ajt.12260

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      The authors report the results of a survey describing the practices of 57 organ procurement organizations in screening deceased organ donors for human immunodeficiency and hepatitis B and hepatitis C viruses, and the ability of most to use nucleic acid testing for screening.

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      Conversion of Twice-Daily Tacrolimus to Once-Daily Tacrolimus Formulation in Stable Pediatric Kidney Transplant Recipients: Pharmacokinetics and Efficacy (pages 2191–2197)

      S. I. Min, J. Ha, H. G. Kang, S. Ahn, T. Park, D. D. Park, S. M. Kim, H. J. Hong, S. K. Min, I. S. Ha and S. J. Kim

      Article first published online: 4 JUN 2013 | DOI: 10.1111/ajt.12274

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      This study highlights that the conversion of twice-daily tacrolimus to once-daily tacrolimus formulation results in highly variable changes in pharmacokinetic parameters of tacrolimus in stable pediatric kidney transplant patients.

  7. Case Reports

    1. Top of page
    2. The AJT Report
    3. Literature Watch
    4. Editorials
    5. Special Article
    6. Original Articles
    7. Brief Communications
    8. Case Reports
    9. Reports From the CDC: MMWR
    10. Images in Transplantation
    11. Letters to the Editor
    12. Errata
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      Mycobacterium llatzerense Lung Infection in a Liver Transplant Recipient: Case Report and Review of the Literature (pages 2198–2200)

      L. Teixeira, R. K. Avery, M. Iseman, A. V. Arrossi, S. Harrington, K. Stephens and C. G. Winans

      Article first published online: 13 JUN 2013 | DOI: 10.1111/ajt.12318

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      The authors describe a case of sub-acute pneumonia in a liver transplant recipient due to Mycobacterium llatzerense, a recently described aerobic, rapidly growing mycobacterium that responded to treatment with ciprofl oxacin, minocycline and azithromycin.

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      Two Patients With History of STEC-HUS, Posttransplant Recurrence and Complement Gene Mutations (pages 2201–2206)

      M. Alberti, E. Valoti, R. Piras, E. Bresin, M. Galbusera, C. Tripodo, F. Thaiss, G. Remuzzi and M. Noris

      Article first published online: 3 JUN 2013 | DOI: 10.1111/ajt.12297

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      Two patients with a clinical history of D+ hemolytic uremic syndrome associated with Shiga-toxin-producing 0157:H7 E. coli and recurrence in the kidney graft carry heterozygous mutations in the genes encoding complement factor I (patient 1) and membrane cofactor protein (patient 2).

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      Combined Pancreatic Islet and Kidney Transplantation in a Child With Unstable Type 1 Diabetes and End-Stage Renal Disease (pages 2207–2210)

      K. A. Benedict, S. Moassesfar, S. Adi, S. E. Gitelman, J. L. Brennan, M. McEnhill, P. G. Stock, A. A. Portale and A. M. Posselt

      Article first published online: 13 JUN 2013 | DOI: 10.1111/ajt.12323

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      The authors present the clinical course of a 6-year-old patient with type I diabetes mellitus and congenital end-stage renal disease who underwent a simultaneous live donor kidney and deceased donor islet transplant.

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      A Single Center Experience of Abdominal Wall Graft Rejection After Combined Intestinal and Abdominal Wall Transplantation (pages 2211–2215)

      B. S. R. Allin, C. D. L. Ceresa, F. Issa, G. Casey, O. Espinoza, S. Reddy, S. Sinha, H. Giele, P. Friend and A. Vaidya

      Article first published online: 9 JUL 2013 | DOI: 10.1111/ajt.12337

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      In a retrospective analysis of patients undergoing combined intestinal and abdominal wall transplantation, an erythematous maculopapular rash occurring prior to rejection of the intestinal component is identified as the presenting feature of rejection of the abdominal wall.

  8. Reports From the CDC: MMWR

    1. Top of page
    2. The AJT Report
    3. Literature Watch
    4. Editorials
    5. Special Article
    6. Original Articles
    7. Brief Communications
    8. Case Reports
    9. Reports From the CDC: MMWR
    10. Images in Transplantation
    11. Letters to the Editor
    12. Errata
    1. You have free access to this content
      Emergence of Avian Influenza A(H7N9) Virus Causing Severe Human Illness—China, February–April 2013 (pages 2216–2221)

      Article first published online: 26 JUL 2013 | DOI: 10.1111/ajt.12420

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      A new severe avian infl uenza virus (H7N9) has been reported in China. Thus far, no human-to-human transmission has occurred and there have been no reports involving organ donors or recipients.

  9. Images in Transplantation

    1. Top of page
    2. The AJT Report
    3. Literature Watch
    4. Editorials
    5. Special Article
    6. Original Articles
    7. Brief Communications
    8. Case Reports
    9. Reports From the CDC: MMWR
    10. Images in Transplantation
    11. Letters to the Editor
    12. Errata
    1. CME

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  10. Letters to the Editor

    1. Top of page
    2. The AJT Report
    3. Literature Watch
    4. Editorials
    5. Special Article
    6. Original Articles
    7. Brief Communications
    8. Case Reports
    9. Reports From the CDC: MMWR
    10. Images in Transplantation
    11. Letters to the Editor
    12. Errata
    1. You have free access to this content
      Donor-Derived Tuberculosis (TB) Infection in Lung Transplant Despite Following Recommended Algorithm (pages 2225–2226)

      D. Kumar, M. Budev, C. Koval, W. C. Hellinger, S. M. Gordon and J. W. Tomford

      Article first published online: 9 JUL 2013 | DOI: 10.1111/ajt.12344

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  11. Errata

    1. Top of page
    2. The AJT Report
    3. Literature Watch
    4. Editorials
    5. Special Article
    6. Original Articles
    7. Brief Communications
    8. Case Reports
    9. Reports From the CDC: MMWR
    10. Images in Transplantation
    11. Letters to the Editor
    12. Errata
    1. You have free access to this content
      Erratum (page 2231)

      Article first published online: 26 JUL 2013 | DOI: 10.1111/ajt.12421

      This article corrects:

      Leptin Modulates Allograft Survival by Favoring a Th2 and a Regulatory Immune Profile

      Vol. 13, Issue 1, 36–44, Article first published online: 27 SEP 2012

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