Edited by: Marek Sanak
Relationship between asthma and cognition: the Cooper Center Longitudinal Study
Article first published online: 15 FEB 2013
© 2013 John Wiley & Sons A/S. Published by Blackwell Publishing Ltd
Volume 68, Issue 4, pages 545–548, April 2013
How to Cite
Relationship between asthma and cognition: the Cooper Center Longitudinal Study. Allergy 2013; 68: 545–548., , , , .
- Issue published online: 19 MAR 2013
- Article first published online: 15 FEB 2013
- Manuscript Accepted: 28 DEC 2012
Minimal data are available on the relationship between asthma and cognitive performance. In this report, we examine the relationship between asthma and cognitive performance in older adults, a subpopulation with elevated risk of cognitive impairment.
We conducted a cross-sectional, retrospective analysis of 1380 participants age ≥55 who completed preventive health examinations at the Cooper Clinic in Dallas, TX. Cognition was assessed using the Montreal Cognitive Assessment (MoCA), a brief test for mild cognitive impairment. Data were analyzed in a multiple logistic regression using MoCA scores suggestive of cognitive impairment as the dependent variable.
When controlling for demographic characteristics, self-rated health status, inhaled corticosteroid use, and FEV1/FVC, asthma were associated with 78% increased risk of cognitive impairment (P = 0.02) as defined by MoCA score.
In the largest sample examined to date, we have identified a significant relationship between asthma and cognitive impairment in older people.