Where to prick the apple for skin testing?

Authors

  • B. J. Vlieg-Boerstra,

    Corresponding author
    • Department of Pediatric Pulmonology and Pediatric Allergy, University Medical Centre Groningen, University of Groningen, Groningen, the Netherlands
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    • At the time of the study. Currently at Emma Children's Hospital, Academic Medical Center, Pediatric Respiratory Medicine and Allergy, University of Amsterdam and Erasmus MC, Department of Internal Medicine, Section Allergology, the Netherlands.
  • W. E. van de Weg,

    1. PlantBreeding, Wageningen University and Research Centre, Wageningen, the Netherlands
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  • S. van der Heide,

    1. Laboratory of Allergy and Pulmonary Diseases, University Medical Centre Groningen, University of Groningen, Groningen, the Netherlands
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  • A. E. J. Dubois

    1. Department of Pediatric Pulmonology and Pediatric Allergy, University Medical Centre Groningen, University of Groningen, Groningen, the Netherlands
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  • Edited by: Reto Crameri

Correspondence

Berber J. Vlieg-Boerstra, Emma Children's Hospital, Academic Medical Centre, Department of Pediatric Respiratory Medicine and Allergy, Meibergdreef 9, 1105AZ Amsterdam, the Netherlands.

Tel.: +31205662851

Fax: +31575560843

E-mail: b.j.vlieg-boerstra@amc.uva.nl

Abstract

Mal d 1 is not equally distributed over the apple. We aimed to examine the influence of the location of pricking in the apple on prick-to-prick skin prick test (PTP) results. PTPs were performed in autumn 2007 and spring 2008, before the birch pollen season, in 32 Dutch adults with symptoms of oral allergy to fresh apple, using apples harvested in autumn 2007. PTPs with fresh intact and unpeeled Pink Lady, Golden Delicious, Elise, Santana and Modi apples were performed using material obtained from approximately 2 cm near the stalk (top), and the middle region. All PTP responses were greater when performed with apple material near the stalk than from the middle region. In 2007, these differences were statistically significant for Pink Lady, Golden Delicious and Elise, and in 2008, for Pink Lady and Modi. When performing PTPs, the apple should be pricked near the stalk rather than in the middle.

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