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Figure S1. Mean percent change (95% CI) from post-saline baseline.

Figure S2. (A) Mean differences (95% CI) between active treatments and placebo from day 1 to day 21, over the allergen challenge time course (EAR and LAR) and to pre-methacholine challenge on day 22 for each treatment. (B) Mean differences (95% CI) between combination and components from day 1 to day 21, over the allergen challenge time course (EAR and LAR) and to pre-methacholine challenge on day 22 for each treatment.

Figure S3. The screening allergen challenge.

Figure S4. The bolus allergen challenge and methacholine challenge.

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