Characteristics of traditional Chinese medicine use in children with asthma: a nationwide population-based study

Authors

  • T.-P. Huang,

    1. Department of Traditional Chinese Medicine, Center for Traditional Chinese Medicine, Chang Gung Memorial Hospital, Taoyuan, Taiwan
    2. Graduate Institute of Traditional Chinese Medicine, School of Traditional Chinese Medicine, Chang Gung University, Taoyuan, Taiwan
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    • These authors contributed equally to this work.
  • P.-H. Liu,

    1. Clinical Informatics and Medical Statistics Research Center, College of Medicine, Chang Gung University, Taoyuan, Taiwan
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    • These authors contributed equally to this work.
  • A. S.-Y. Lien,

    1. School of Nursing, College of Medicine, Chang Gung University, Taoyuan, Taiwan
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  • S.-L. Yang,

    1. Department of Traditional Chinese Medicine, Center for Traditional Chinese Medicine, Chang Gung Memorial Hospital, Taoyuan, Taiwan
    2. Graduate Institute of Traditional Chinese Medicine, School of Traditional Chinese Medicine, Chang Gung University, Taoyuan, Taiwan
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  • H.-H. Chang,

    1. Department of Traditional Chinese Medicine, Center for Traditional Chinese Medicine, Chang Gung Memorial Hospital, Taoyuan, Taiwan
    2. Graduate Institute of Traditional Chinese Medicine, School of Traditional Chinese Medicine, Chang Gung University, Taoyuan, Taiwan
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  • H.-R. Yen

    Corresponding author
    1. Department of Traditional Chinese Medicine, Center for Traditional Chinese Medicine, Chang Gung Memorial Hospital, Taoyuan, Taiwan
    2. Graduate Institute of Traditional Chinese Medicine, School of Traditional Chinese Medicine, Chang Gung University, Taoyuan, Taiwan
    3. Chinese Herbal Medicine Research Team, Healthy Aging Research Center, Chang Gung University, Taoyuan, Taiwan
    4. Research Center for Traditional Chinese Medicine, Department of Chinese Medicine and Department of Medical Research, China Medical University Hospital, Taichung, Taiwan
    5. School of Chinese Medicine, China Medical University, Taichung, Taiwan
    • Correspondence

      Dr. Hung-Rong Yen, Department of Traditional Chinese Medicine, Center for Traditional Chinese Medicine, Chang Gung Memorial Hospital, 123 Ding-hu Road, Kweishan, Taoyuan 333, Taiwan.

      Tel.: +886-3-319-6200 ext 2611

      Fax: +886-3-329-8995

      E-mail: hungrongyen@gmail.com

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  • Edited by: Michael Wechsler

Abstract

Asthma is a chronic inflammatory airway disease accounting for severe morbidity and mortality in children. To determine the characteristics of traditional Chinese medicine (TCM) used to treat pediatric asthma, we conducted a nationwide population-based study by analyzing a cohort of one million randomly sampled patients from the beneficiaries of the National Health Insurance Program in Taiwan from 2002 to 2010. Children under 18 years of age with newly diagnosed asthma (ICD-9-CM code: 493, = 45 833) were enrolled, and 57.95% (N = 26 585) of them had used TCM. The number of TCM users was significantly more than that of non-TCM users in school-age children. The most commonly prescribed TCM formula is Ding-chuan-tang, or Xing-ren (Semen Armeniacae Amarum) for the single herb. Our study is the first to reveal characteristics and prescription patterns of the use of TCM in children with asthma. Further research is needed to elucidate the efficacy and safety of these Chinese herbal products.

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