Edited by: Hans-Uwe Simon
An important role of tumor necrosis factor receptor-2 on natural killer T cells on the development of dsRNA-enhanced Th2 cell response to inhaled allergens
Article first published online: 6 NOV 2013
© 2013 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd
Volume 69, Issue 2, pages 186–198, February 2014
How to Cite
An important role of tumor necrosis factor receptor-2 on natural killer T cells on the development of dsRNA-enhanced Th2 cell response to inhaled allergens. Allergy 2014; 69: 186–198., , , , , , , , , .
- Issue published online: 27 JAN 2014
- Article first published online: 6 NOV 2013
- Manuscript Accepted: 14 SEP 2013
- Korea Ministry of Health & Welfare, Republic of Korea. Grant Number: HI 13C 0040-010013
|all12301-sup-0001-FigS1.eps||image/eps||1103K||Figure S1. Allergen-specific Th2 and Th17 cytokines enhanced by low-dose dsRNA are downregulated in the absence of type I NKT cells. Cells in WT and Jα18-deficient mice, that were sensitized with OVA or OVA + 0.1 μg of poly[I:C], were isolated from lung-draining lymph node and lung tissues and then incubated with PBS or OVA for 72 h. The production of each cytokine was measured in supernatant fraction. *P < 0.05; **P < 0.01; ***P < 0.001 relative to OVA groups; #P < 0.05; ##P < 0.01; ###P < 0.001; n.s.: not significant.|
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