Subjective memory complaints in elders: depression, anxiety, or cognitive decline?
Article first published online: 6 DEC 2012
© 2012 John Wiley & Sons A/S
Acta Neurologica Scandinavica
Volume 127, Issue 5, pages 344–350, May 2013
How to Cite
Subjective memory complaints in elders: depression, anxiety, or cognitive decline? Acta Neurol Scand: Doi: 10.1111/ane.12038. © 2012 John Wiley & Sons A/S, , , , , .
- Issue published online: 13 APR 2013
- Article first published online: 6 DEC 2012
- Manuscript Accepted: 2 OCT 2012
- mild cognitive impairement
To study the association of subjective memory complaints (SMC) with affective state and cognitive performance in elders.
Materials and methods
We studied community dwelling elderly persons with normal physical examination. Participants completed questionnaires regarding memory difficulties and lifestyle habits, the Geriatric Depression Scale (GDS) and the Spielberger State-Trait Anxiety Inventory (STAI). Depending on their answers to the question about their memory condition, participants were divided into complainers and non-complainers and to five groups according to their MMSE scores. These data have been compared to objective cognitive performance according to Mindstreams - a computerized neuropsychological battery. A logistic regression was performed to evaluate odds ratios (OR) and 95% confidence intervals (CI) for those factors, which were associated with SMС (dependent variable).
Of 636 consecutive subjects (61% females), 507 participants (79.7%) had SMС. Presence of SMC was inversely correlated with MMSE scores, (r = −0.108; P for trend = 0.007). GDS and STAI scores were higher among subjects with SMC (OR = 1.23: CI 95%: 1.1–1.36 and OR = 1.03: CI 95%: 1.01–1.07, respectively). SMC did not correlate with objective cognitive performance measured by Mindstreams.
Subjective memory complaints are associated with sub-syndromal depression and anxiety in healthy cognitively normal elders.